Introduction to Medical Immunology - part 3 ppsx
Introduction to Medical Immunology - part 3 ppsx
... by Factor I and its cofactors (Factor H or CR1). 3. Binding of Factor B to C3b leading to C3bB. 4. Activation of the bound B by D leading to C3bBb. 5. C3bBb activation of more C3, leading to formation ... stages of CD8-mediated cytotoxicity? A. CD2 : CD58 (LFA -3 ) B. CD8 : MHC-I C. CD95 (Fas) : Fas ligand D. IL-2 : IL-2R E. Interferon- γ (IFN- γ ) : IFN- γ R 11 .3 The developme...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 1 pot
... Immunology Jean-Michel Goust, George C. Tsokos, and Gabriel Virella 18. Tolerance and Autoimmunity 33 5 Christian C. Patrick, Jean-Michel Goust, and Gabriel Virella 19. Organ-Specific Autoimmune Diseases 36 3 Jean-Michel ... Diseases 36 3 Jean-Michel Goust and George C. Tsokos 20. Systemic Lupus Erythematosus 38 3 Jean-Michel Goust 21. Rheumatoid Arthritis 39 9 Gabriel Virella 22. Hype...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 2 potx
... CD40 ligand (CD40L, CD154, gp39), LFA-1 and ICAM-1. These molecules have counterparts on the APC: CD58 (LFA -3 ) , CD80/86, CD40, ICAM-1, and LFA-1 (ICAM-1 and LFA-1 are expressed in both cell ... the ability to bind to high- affinity Fc ε receptors) after heating at 56°C for 30 minutes. This binding depends on the tertiary structure of the C- terminal portion of C ε 2 and the N-termi...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 4 pps
... IL-2, interferon- γ , lymphotoxin (TNF- β ), and TNF- α . c. Patients infected by bacteria able to release large amounts of superantigens (e.g., S. aureus- releasing enterotoxins or TSST-1 ... bound complement, particularly C3. Absorption of C3b -containing circulating antigen-antibody complexes to the CR1 expressed by red cells allows the parasite to gain access to the red cell,...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 5 ppt
... chronic granulomatous diseases of childhood. JAMA, 2 63: 1 533 , 1990. Page 33 5 18 Tolerance and Autoimmunity Jean-Michel Goust, George C. Tsokos, and Gabriel Virella I. Historical Introduction A. ... glomerulonephritis Anti-C3bBb antibodies (nephritic factors) bind to and stabilize the C3 convertase (C3bBb) which cleaves C3. Phagocytosis and intracellular lysis Autoimmune cyt...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 6 ppt
... MHC-II+ macrophages E. RF-producing plasmablasts 21.8 Which one of the following cytokines is usually undetectable in rheumatoid synovial fluid? A. GM-CSF B. IL-2 C. IL-4 D. IL-8 E. Interferon- γ 21.9 ... of vascular hyper- Page 39 9 21 Rheumatoid Arthritis Jean-Michel Goust I. Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammatory and d...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 7 pps
... destruction of Rh-positive erythrocytes after exposure to IgG anti-D antibodies is due to: A. Complement activation B. Fc-mediated phagocytosis C. C3b-mediated phagocytosis D. C3d-mediated phagocytosis E. ... complement. 3. The most potentially pathogenic IC are those of intermediate size (Ag 2 -3 .Ab 2-6 ), particularly when involving complement-fixing antibodies (IgG1, IgG3) of mo...
Ngày tải lên: 10/08/2014, 00:21
Introduction to Medical Immunology - part 10 doc
... reaction), 6 4-6 5, 30 9 -3 11 Molecular mimicry, 35 4, 35 5 Monoclonal antibodies, anti-CALLA, 571 anti-CD3, 30 6 anti-T-cell, 35 8 Page 634 [Human leukocyte antigens (HLAs)] Bw35, 45 Bw 53, 42 cell-mediated ... protein), 198 Mitogenic stimulation assays, 30 5 -3 06 Mitogens, 30 5 Mitosis, in CD4+ activation, 19 4-1 95 Mixed-lymphocyte cultures, 519 Mixed-lymphocyte reaction (M...
Ngày tải lên: 10/08/2014, 00:21
introduction to medical immunology
... Dw1,w2 B. A2 ,3; Cw1,w2; B5,8; Dw2 ,3 C. A1 ,3; Cw1,w3; B5,8; Dw1,w4 D. A1 ,-; Cw1,w2; B 5-; Dw1,w3 E. A 3- ; Cw2,w3; B8 ,-; Dw3,w4 3. 4 Which of the following is a unique characteristic of class I MHC proteins? A. ... associations of MHC-I and non-self peptides; occupancy of the binding site on the TcR by MHC-I-associated peptide provides the antigen-specific signal that drives cy...
Ngày tải lên: 11/04/2014, 09:48
An introduction to multiagent systems - part 3 docx
... discussed. The XOR, OR-of-XORs, XOR-of-OR, OR/XOR, and OR* languages are all powerful enough to express all valuations. Second, the efficiencies of the OR-of- XOR and XOR-of-OR languages are incomparable: ... 2 m/2+1 to express in the OR-of-XOR language. It is also possible to define a language of XOR-of-OR bids, and even a lan- guage allowing arbitrary nesting of OR and XOR statements her...
Ngày tải lên: 08/08/2014, 11:21