Neuroimmunology in Clinical Practice - part 10 pps
Neuroimmunology in Clinical Practice - part 10 pps
... vasculopathy 230–1 innate immunity 3 interferon-gamma 5 internodal proteins 13–17 CD9 13 myelin-associated glycoprotein 13–14 myelin-associated oligodendrocyte basic protein 14–15 myelin basic protein 14 myelin ... 03/05/2007 10: 50 AM Page 248 Index 261 oligodendrocyte-myelin glycoprotein 16 peripheral myelin protein (PMP22) 16 proteolipid protein (PLP1) 16–17 T-lymphocyte maturation-associ...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 7 pps
... benefits. Cyclosporine A is an immunosupressant that blocks interleukin-2 activation of T-helper cells by inhibit- ing calcineurin. While a controlled, double-blind clinical trial has shown its effectiveness in ... screening for immunocytochemical staining for proteins known to be associated with muscular dystrophies is appropriate. The main finding in DM is perivascular B-cell-predominan...
Ngày tải lên: 10/08/2014, 00:20
Chapter 003. Decision-Making in Clinical Medicine (Part 10) pps
... harmful intervention, such as smoking or overeating to develop obesity. The major difference between a well-done clinical trial and a well-done prospective observational study of a particular ... address certain regulatory requirements that may result in a different trial design from what practicing clinicians would find useful. Meta-Analysis The Greek prefix meta signifies somethi...
Ngày tải lên: 06/07/2014, 08:20
Neuroimmunology in Clinical Practice - part 1 ppt
... that are incor- porated into compact myelin. Interestingly, one of the MOBP isoforms (MOBP155) includes tandem repeats of a proline-rich domain, suggesting it may interact with other proteins (Yamamoto ... fields in medicine, has evolved into a framework of rapidly developing sub- specialties increasingly dependent on technology- driven advances in clinical and basic sciences. Neuroimmu...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 2 pdf
... assists their invasion into the CNS. Chemokines, including interferon γ-inducible protein -1 0 and its receptor CXCR3, are elevated in patients with disease activity. The sequence of tethering, adhesion, ... four clinical courses that are routinely used in practice (Lublin and Reingold, 1996). This empirical classification, in agreement with natural history studies, distinguishes re...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 3 pdf
... cells; anti-CD4; integrin inhibitors Lymphocyte-specific cytoplasmic protein – tyrosine kinase P56lck; zeta-associated protein (ZAP )-7 0; protein kinase C theta; mitogen-activated protein kinase; nuclear factor ... the high-affinity interleukin-2 receptor, anti-CD25); alemtuzumab (anti-CD52, Campath 1H); rituximab (anti-CD20); anti-CD40L/-CD154 (IDEC-131); anti-IL-12, anti-CD6; anti-CD3 (OK...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 4 pot
... Progressive Efficacy Clinical Trial of Recombinant Interferon-beta-1a in MS (SPECTRIMS) Study Group. 2001. Randomized controlled trial of interferon-beta-1a in secondary progressive MS: Clinical results. ... 2006. Interferon-beta-1a slows down progression of brain atrophy in relapsing-remitting multiple sclerosis by reducing predominantly grey matter atrophy pro- gression. Mult Scle...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 5 potx
... plasmapheresis in acute disseminated (post- infectious) encephalomyelitis. J Clin Apheresis, 7(4), 173 –9. Sugita, K., Suzuki, N., Shimizu, N. et al. 1993. Involvement of cytokines in N-methyl-N’-nitro-N- nitrosoguanidine-induced ... identified. Inter- leukin 23 (IL-23) may play an important role in the early effector phase of immune-mediated peripheral nerve demyelination in EAN, as w...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 6 pdf
... consistent benefit include indomethacin, somatostatin analogs, caffeine, ergot alkaloids, and nocturnal desmopressin. L-threo-3, 4-dihydroxyphenylserine is used in the rare but dis- tinctive entity, ... heart rate increase of 30 beats per minute or rate exceeding 120 and ortho- static complaints within five minutes of standing at some point in the illness are characteristic and are con- s...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 8 ppt
... GluR1 AGNA-1; ANNA-1,2,3; PCA-2; Ma2; CRMP-5; VGCC (P/Q>N-type) Amphiphysin CRMP-5; ANNA-1; 2, PCA-2 CRMP-5; recoverin CRMP-5; VGCC; amphiphysin; ganglionic AChR; VGKC; ANNA-1,2 ANNA-1; CRMP-5; ... blocked acetylcholine-induced increase in intracellular free calcium and inhibited 125 I-α-bungarotoxin bind- ing in cells expressing α7nAChR. The authors postulate that these antibodies...
Ngày tải lên: 10/08/2014, 00:20