reflective learning in clinical practice

... just beginning. In such instances, the experiences related to more common tumor types may inform trials on these more rare clinical entities. Interest in neoadjuvant chemotherapy also intensifies ... APPLICATIONS IN CLINICAL PRACTICE Edited by Oliver F. Bathe           Neoadjuvant Chemotherapy – Current Applications in Clinical Practice Edited by Oliver F. Bathe Published by InTech ... or lapatinib, or both in the preoperative setting Several other trials are ongoing to evaluate these 2 drugs in the neoadjuvant setting, including Neo-ALTTO (Neoadjuvant Lapatinib and/or......

Ngày tải lên: 27/06/2014, 13:20

... complementary-determining regions (CDR), Light chain Heavy chain Antigenbinding site VH Complementarydetermining regions (CDR) VL CH1 CL CH2 FC region Fc receptor complement binding site CH3 Fig ... glycoprotein with a single transmembrane domain and is targeted to axons underlying paranodal regions of myelin sheaths in the CNS and PNS (Einheber et al., 19 97) This protein participates in ... of cytokines by recombinant vaccinia viruses: A model for studying cytokines in viral infections in vivo Immunol Rev, 12 7, 15 7–82 Reynolds, D.S., Boom, W.H and Abbas, A.K 19 87 Inhibition...

Ngày tải lên: 10/08/2014, 00:20

... three months or more after the clinical onset, a gadoliniumenhancing lesion (not at the site involved in the original clinical event) is needed; if no enhancing lesion is present, a follow-up ... deficient in. .. criteria of dissemination in time 2 Incorporation of spinal cord lesions into the imaging requirements: A spinal lesion characteristic of MS (little or no swelling in the ... 20 01; Pettinelli and McFarlin, 1981) Myelin basic protein is one of these proteins T cells reactive with myelin basic protein can be demonstrated in individuals with MS and in normal controls...

Ngày tải lên: 10/08/2014, 00:20

... disabling in MS, and significantly interfere with professional and social functioning. The combination of abnormal- ities in attention, planning, working memory, speed of information processing ... protein – tyrosine kinase P56lck; zeta-associated activation, signaling and protein (ZAP )-7 0; protein kinase C theta; mitogen-activated protein kinase; nuclear factor of activated T cells; inhibitors ... finding (Secondary Progressive Efficacy Clinical Trial of Recombinant Interferon-beta-1a in MS (SPECTRIMS) Study Group, 2001) Improvements in some... proliferation Janus protein tyrosine kinase...

Ngày tải lên: 10/08/2014, 00:20

... against mouse brain sections in an indirect immunofluorescence assay. A distinct IgG binding pattern associated with capillaries and the blood–brain barrier in the cerebellar cortex, midbrain, ... 2006. Interferon-beta-1a slows down progression of brain atrophy in relapsing-remitting multiple sclerosis by reducing predominantly grey matter atrophy pro- gression. Mult Scler, in press. Zivadinov, ... rate in the relapsing group. The survival rate at five years was 90% in the monophasic and 68% in the relaps- ing group (Wingerchuck et al., 1999). Predictors of relapsing course included longer interattack...

Ngày tải lên: 10/08/2014, 00:20

... Saperstein, 2001 Definite: clinical phenotype, NCS, CSF, and biopsy Probable: clinical phenotype, NCS, and CSF Possible: clinical phenotype and NCS Definite: clinical major, NCS, and CSF Probable: clinical ... changes, in which case the term retrobulbar ON is applied The diagnosis of ON is made on the basis of a combination of clinical and laboratory findings In subtle cases, diagnosis can be clinically ... instances the entire spine is involved as well as some of the brainstem In some instances the in? ??ammatory sensitization involves both central and peripheral (e.g spinal root) myelin (Abramsky and Teitelbaum,...

Ngày tải lên: 10/08/2014, 00:20

... T-helper cells by inhibit- ing calcineurin. While a controlled, double-blind clinical trial has shown its effectiveness in MG (Tindell et al., 1993), significant side effects and drug interactions ... terminal. Guanidine increases calcium within the nerve ter- minal by inhibiting uptake of calcium by subcellular organelles (Kamenskaya et al., 1975). While guani- dine is occasionally utilized in ... of obtaining a meaningful biopsy result It also may be helpful in distinguishing active in ammation from atrophy The MRI techniques used include T1and T2-weighted images with T2 being sensitive...

Ngày tải lên: 10/08/2014, 00:20

... acetylcholine-induced increase in intracellular free calcium and inhibited 125 I-α-bungarotoxin bind- ing in cells expressing α7nAChR. The authors postulate that these antibodies may act by blocking the ... Hashimoto’s disease. Rinsho Shinkeigaku, 32, 191–8. Zettinig, G., Asenbaum, S., Fueger, B.J. et al. 2003. Increased prevalence of subclinical brain perfusion abnormalitis in patients with autoimmune ... but imaging is unrevealing in about half of the patients. Autopsy reports usually reveal perivenular and arteriolar in? ??ltration by pre- dominantly T lymphocytes throughout the brain including the...

Ngày tải lên: 10/08/2014, 00:20

... perivascular in? ??ammation of the adventitia, and intimal prolifera- tion resulting in narrowing of arterial lumina. Later investigators (Kernohan and Woltman, 1938) sum- marized the clinical and ... Yamashiro et al., 199 7) Sydenham’s chorea... in ammatory lesions and related clinical and pathological findings in 20 patients with insulin and non-insulin dependent diabetes mellitus (IDDM, NIDDM) ... the internal elastic lamina and virtually the entire media (arrows). Marked intimal proliferation has nearly occluded the lumen, and few in? ??ammatory cells remain (stain, hematoxylin and eosin;...

Ngày tải lên: 10/08/2014, 00:20

... 19–20 myelin-associated glycoprotein 13–14 myelin-associated oligodendrocyte basic protein 14–15 myelin basic protein 14 myelin lipids 19 myelin oligodendrocyte glycoprotein 15 myelin protein zero ... in bold... proteins 17–19 claudin 11 17–18 claudin 19 18 contactin 18 contactin-associated protein 18 neurofascin 18–19 INDEX peripheral autonomic neuropathies 142 peripheral myelin protein ... glycoprotein 15 myelin protein zero 15 Nogo 15–16 NICP_D01 03/05/2007 10: 54 AM Page 261 Index oligodendrocyte-myelin glycoprotein 16 peripheral myelin protein (PMP22) 16 proteolipid protein... myelin...

Ngày tải lên: 10/08/2014, 00:20

... in mind during the independent peer review of the preclinical data Only when the compelling preclinical data are available, careful and incremental testing in patients is justified Preclinical ... interaction, between preclinical and clinical investigators, is strongly encouraged The clinical trials of SC based interventions must follow internationally accepted principles governing the ethical ... main clinical trials dividing them basing on their clinical applications, and taking into account the ethical issue associated with the stem cell therapy. Methods: We have searched Pubmed/Medline...

Ngày tải lên: 10/08/2014, 10:20

... of research findings in clinical practice within mental health care settings Journal of Advanced Nursing 1995, 22(5):855-861 89 Linde BJ: The effectiveness of three interventions to increase research ... clinicians’ and investigators’ ability to directly compare findings from various studies to determine the extent to which nurses use research in clinical practice In this review, by quantifying ... implement research findings Journal of Advanced Nursing 1986, 11(4):389-394 16 Bircumshaw D: The utilization of research findings in clinical nursing practice Journal of Advanced Nursing 1990, 15:1272-1280...

Ngày tải lên: 10/08/2014, 10:23

... combines e -learning with standard teaching methods and various teaching /learning me dia. Thus, learning content is conveyed face-to-face as well as via web- based training (WBT), CD-Rom, or print ... points gained for attendance of the QC meetings and? ?in case of blended learning? ??for the online modules. Intervention AllGPsinoneQCwererandomisedasaclusterto study arm A (blended learning? ??online ... blended learning approach, in which online modules were combi ned with discussions in QCs, was not superior in knowledge gain to the traditional learning approach in which lectures were combined...

Ngày tải lên: 11/08/2014, 05:21

... decision-making in clinical practice Implementation Science 2006, 1:16 decision making[63] Therefore, in order to not increase inequity in health (patients who are not invited to be involved in decision ... decisionmaking in their clinical practice These results should improve our understanding on how to effectively translate shared decision-making into health professionals' clinical practice Except ... expanding on these codes by readings of the text"[26] The beginning set of a priori codes was based on a taxonomy of barriers and facilitators to implementing clinical practice guidelines in actual...

Ngày tải lên: 11/08/2014, 05:22

... combines e -learning with standard teaching methods and various teaching /learning me dia. Thus, learning content is conveyed face-to-face as well as via web- based training (WBT), CD-Rom, or print ... points gained for attendance of the QC meetings and? ?in case of blended learning? ??for the online modules. Intervention AllGPsinoneQCwererandomisedasaclusterto study arm A (blended learning? ??online ... blended learning approach, in which online modules were combi ned with discussions in QCs, was not superior in knowledge gain to the traditional learning approach in which lectures were combined...

Ngày tải lên: 11/08/2014, 16:20

... Targets in Clinical Practice: Glycemic Targets in Clinical Practice: Postprandial vs Preprandial Postprandial vs Preprandial and Fasting? and Fasting? Steven D Wittlin MD Steven D Wittlin MD ... Glucose Control Clinically ??     Frequent fingersticks HbA1C Fructosamine Continuous Glucose Monitoring Systems    Historical Real-time 1,5 Anhydroglucitol Postprandial Index vs A1C/1,5-AG ... 1998;21:336–40 Changes in Postprandial Glucose Metabolism in. .. analogues  DPP-IV inhibitors Pramlintide  Glycemic Index/Load  Importance of Post-Prandial Control in Managing Gestational...

Ngày tải lên: 13/08/2014, 09:38

... cauda equina tumours... as urinary retention Urinary tract infection is usually associated with urethral burning or scalding on voiding; frequent, low-volume voiding; and a feeling of incomplete ... surgical conditions cause abdominal pain and... abdomen and inferiorly to the ipsilateral groin The intensity may increase rapidly, reaching a peak within minutes or may increase more slowly over ... the pain include pins and needles in the hands or feet, weakness in the arms (cervical cord) or legs (lumbosacral spine), urinary symptoms such as hesitancy and a poor urinary... spinal cord...

Ngày tải lên: 14/08/2014, 11:20

... gồm: máy chủ, máy in 10 máy tính nối mạng, cài đặt phần mềm học lý thuyết Cục Đường Việt Nam chuyển giao Cơ sở đào tạo có lưu lượng 500 học viên trở lên phải có 20 máy tính để học sinh ôn luyện phần ... đào tạo lái xe b) Phòng học chuyên môn bảo đảm diện tích tối thiểu 50m2 cho lớp học không 35 học sinh; c) Được chiếu sáng tự nhiên trực tiêu chuẩn ánh sáng, xa tiếng ồn, bảo đảm môi trường sư phạm ... viết Phiếu nhận hồ sơ hẹn ngày trả kết Phòng Quản lý sát hạch lái xe phối hợp Sở Lao động Thương Binh xã hội : kiểm tra lập biên bản, Trình ký văn đề nghị Cụ Đường Bộ Việt Nam cấp lại phép đào tạo...

Ngày tải lên: 02/07/2014, 22:20