Neuroimmunology in Clinical Practice - part 7 pps
Neuroimmunology in Clinical Practice - part 7 pps
... screening for immunocytochemical staining for proteins known to be associated with muscular dystrophies is appropriate. The main finding in DM is perivascular B-cell-predominant in amma- tion ... terminal. Guanidine increases calcium within the nerve ter- minal by inhibiting uptake of calcium by subcellular organelles (Kamenskaya et al., 1 975 ). While guani- dine is occasionally utilized...
Ngày tải lên: 10/08/2014, 00:20
Neuroimmunology in Clinical Practice - part 10 pps
... vasculopathy 230–1 innate immunity 3 interferon-gamma 5 internodal proteins 13– 17 CD9 13 myelin-associated glycoprotein 13–14 myelin-associated oligodendrocyte basic protein 14–15 myelin basic protein 14 myelin ... 14 myelin lipids 19 myelin oligodendrocyte glycoprotein 15 myelin protein zero 15 myelin sheath 11, 12 myelin and T-lymphocyte protein (MAL) 17 myelitis 47 8 acute transverse 1...
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Neuroimmunology in Clinical Practice - part 1 ppt
... 04/05/20 07 12:27PM Page 15 Foreword Neuroimmunology in Clinical Practice provides a use- ful and comprehensive review of the field of clinical neuroimmunology. In addition to presenting timely updates ... that are incor- porated into compact myelin. Interestingly, one of the MOBP isoforms (MOBP155) includes tandem repeats of a proline-rich domain, suggesting it may interact with...
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Neuroimmunology in Clinical Practice - part 2 pdf
... whereas animals deficient in IL-12 alone develop severe dis- ease. Interleukin-23 induces IL- 17 production by T cells. IL- 17 is expressed in brain lesions and appears to be a regulator of CNS in ammation. T ... the BBB and invasion of the brain parenchyma. In both EAE and MS, levels of gelatinase B (MMP-9) and matrilysin (MMP -7 ) are increased in blood, CSF, and brain during per...
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Neuroimmunology in Clinical Practice - part 3 pdf
... cells; anti-CD4; integrin inhibitors Lymphocyte-specific cytoplasmic protein – tyrosine kinase P56lck; zeta-associated protein (ZAP ) -7 0; protein kinase C theta; mitogen-activated protein kinase; nuclear factor ... IN- 1 (anti-Nogo-A mAb) Pyrimadine synthesis inhibitor (teriflunamide); CCI -7 7 9 (ester or sirolimus); FTY720 (inhibits T-cell circulation); xaliproden (inhibits cytokine synth...
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Neuroimmunology in Clinical Practice - part 4 pot
... 2006. Interferon-beta-1a slows down progression of brain atrophy in relapsing-remitting multiple sclerosis by reducing predominantly grey matter atrophy pro- gression. Mult Scler, in press. Zivadinov, ... chain complex. Cell, 57, 1095–100. Secondary Progressive Efficacy Clinical Trial of Recombinant Interferon-beta-1a in MS (SPECTRIMS) Study Group. 2001. Randomized controlled trial of...
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Neuroimmunology in Clinical Practice - part 5 potx
... Suzuki, N., Shimizu, N. et al. 1993. Involvement of cytokines in N-methyl-N’-nitro-N- nitrosoguanidine-induced plasminogen activator activity in acute disseminated encephalomyelitis and multiple ... identified. Inter- leukin 23 (IL-23) may play an important role in the early effector phase of immune-mediated peripheral nerve demyelination in EAN, as well as in human GBS. IL-23 is hig...
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Neuroimmunology in Clinical Practice - part 6 pdf
... consistent benefit include indomethacin, somatostatin analogs, caffeine, ergot alkaloids, and nocturnal desmopressin. L-threo-3, 4-dihydroxyphenylserine is used in the rare but dis- tinctive entity, ... Marmiroli, P., Baldini, L. et al. 19 87. Peripheral neuropathy in macroglobulinemia – Incidence and antigen-specificity of M-proteins. Neurology, 37, 1506–14. Oh, S.J. 1 977 . Subacute dem...
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Neuroimmunology in Clinical Practice - part 8 ppt
... GluR1 AGNA-1; ANNA-1,2,3; PCA-2; Ma2; CRMP-5; VGCC (P/Q>N-type) Amphiphysin CRMP-5; ANNA-1; 2, PCA-2 CRMP-5; recoverin CRMP-5; VGCC; amphiphysin; ganglionic AChR; VGKC; ANNA-1,2 ANNA-1; CRMP-5; ... blocked acetylcholine-induced increase in intracellular free calcium and inhibited 125 I-α-bungarotoxin bind- ing in cells expressing α7nAChR. The authors postulate that these antibodies...
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Neuroimmunology in Clinical Practice - part 9 pot
... solution using the same manufacturing method was licensed in 1992. Solvent detergent treatment, including partitioning steps and incubation at low pH in the final container has been effective in the ... and exten- sion into the brain involving veins and arteries of varying caliber. The clinicopathological syndrome was delineated and so named for the distinctive pathology (Cravioto and Fe...
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