Báo cáo y học: "Reduced levels of two modifiers of epigeneti

Báo cáo y học: "Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic nois" pdf

... Biology 2010, 11:R111 http://genomebiology.com/2010/11/11/R111 Page 3 of 10 RESEA R C H Open Access Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased ... [http://www.ncbi.nlm.nih.gov/geo/query/ acc.cgi?acc = GSE23512]. doi:10.1186/gb-2010-11-11-r111 Cite this article as: Whitelaw et al.: Reduced levels of two mo...

Ngày tải lên : 09/08/2014, 22:23

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Báo cáo y học: " Reduced levels of two modifiers of epigenetic gene silencing" ppsx

... [http://www.ncbi.nlm.nih.gov/geo/query/ acc.cgi?acc = GSE23512]. doi:10.1186/gb-2010-11-11-r111 Cite this article as: Whitelaw et al.: Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic ... (MommeDs) to study the role of epigenetic reprogramming in whole organisms and populations. Mice with reduced lev...

Ngày tải lên : 09/08/2014, 22:23

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Báo cáo y học: " Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells" pdf

... 5c). Strikingly, 27% and 11% genes of the former group harbored combinations of two or three motifs, whereas only 4% and zero genes of the latter group contained such binary and ternary motif combinations. ... 10% of expressed genes. In contrast, 26% of the genes in the lower 10th percentile of TFIIB occ upancy are expressed above average, and only 2% of those are am...

Ngày tải lên : 09/08/2014, 20:21

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Báo cáo y học: "Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports." pdf

... characterised by a chronic inflammation of the lachrymal and salivary glands, which leads to exocrine hypofunction and the well recognised clinical features of dry eyes (xerophthal- mia) and dry mouth ... et al.: Psychiatric disorder as clinical presentation of primary Sjögren’s syndrome: two case reports. Annals of General Psychiatry 2010 9:12. Pelizza et al. Annals of Gene...

Ngày tải lên : 08/08/2014, 23:21

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Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx

... the time-point of flare. Both individually and collectively, signifi- cant correlations were found between anti-CRP levels and several clinical and laboratory disease activity measures, namely serum levels ... blood lymphocytes [38,39] and accelerated apoptosis of lymphocytes from SLE patients [7], we find the inverse relation between high anti-CRP levels and lymphopenia i...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx

... neuronal degeneration in SLE. Finally, the increased TGF-β levels observed may support a notion of an ongoing anti- inflammatory response counteracting tissue injury caused by CNS lupus. Keywords: amyloid ... degeneration and amyloidogenesis. One hundred and fourteen patients with SLE and age-matched controls were evaluated clinically, with magnetic resonance imaging of the brai...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity" ppsx

... Smad6 and Smad7) immunohistochemically in the cartilage of knee joints of young and old mice. In addi- tion, we assessed whether these expression levels were altered differently in young and old ... medial and lateral tibial cartilage of 5 month and 2 year old C57Bl/6 miceNumber of cells in medial and lateral tibial cartilage of 5 month and 2 year old C57Bl/6 mice....

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Reduced number and impaired function of circulating progenitor cells in patients with systemic lupus erythematosus" pot

... http://arthritis-research.com/content/9/4/R84 Page 5 of 10 (page number not for citation purposes) Figure 2 Adhesion assay and number and morphology of colony forming units (CFU)Adhesion assay and number and morphology of colony forming ... shown). Formation of CFU Functionality of the cultured CPCs was determined in different ways, that is, CFU potential, migratory capacity...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt

... slightly increased proportions of memory B and T cells, suggesting increased chronic low-grade activation of the immune system in first-degree relatives. However, only the deficiency of NKT cells was ... pred- nisone dose or use of cytotoxic medications and several of the cellular phenotypes examined. An increased dose of pred- nisone was negatively correlated with the n...

Ngày tải lên : 09/08/2014, 13:21

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Báo cáo y học: "Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis" docx

... various cell types [2,3] and originating from a gene on chromosome 9 program the synthesis of intracellular gelsolin (cGSN) and of its secreted counterpart. The two isoforms are structurally and functionally ... depletion, however, hypothetically accommodates dysfunctional and destructive actions of the mediators, leading to secondary organ damage and even death. This set...

Ngày tải lên : 09/08/2014, 13:22

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