... 25 to 50 mg/day to commonly used anti-Parkinsonian drugs,significantly improved the primary symptoms of patientswith advanced Parkinson’s disease, possibly by activatio n of dopamine synthesis, ... details1Department of Neuroscience, Section of Psychiatry, University of Genova,Genoa, Italy.2Department of Hematology and Oncology, Section of Semeiotics and Medical Methodology I, University of Genova, ... eligiblepatients started taking duloxe tine 60 mg/day once a dayafter being evaluated by means of the HAM-D, Hamil-ton Scale for Anxiety (HAM-A) [22], Young Mania Rat-ing Scale (YMRS) [23] and the...