báo cáo khoa học: "Best linear unbiased prediction when error vector is correlated with other random vectors in the model" pptx

... Prédiction linéaire, vecteurs corrélés. I. Introduction In mixed linear models, the covariances among the residual or error vector with other random factors in the model are ... y in which the covariances between random vectors with residual vectors are zero is the key to the solution. Computational difficulties depend on th...

Ngày tải lên: 09/08/2014, 22:23

... the integrin I domain of BchD into contact with the integrin-binding motif of BchH, simultaneously triggering porphyrin metallation. This would also lead to a release of the blockade of the ATP-binding ... binding of I to D is not enough to maintain the D subunit in the cell. Our study suggests that ATP hydrolysis is important for a mechanistic step after the formation o...

Ngày tải lên: 19/02/2014, 12:20

... involved in the interaction with the small protein. It is likely that the introduction of the negative charge destabilizes the S loop, thus indicating that this loop, in addition to its role in the ... mechanism of GAPDH could be essential for the binding of CP12. The presence of this region at the interface of GAPDH and CP12 could also explain the kinetic change...

Ngày tải lên: 19/02/2014, 16:20

... domains of the monomer participate in the dimer interactions (Fig. 4, residues marked ÔdÕ), with most residues at the interface coming from the PYR and PP domains. This is in agreement with the ... prevent the C-terminal helix from approaching the other subunit in the dimer sufficiently to shield the active site, as it does in ZmPDC and IPDC. There is theref...

Ngày tải lên: 20/02/2014, 11:20

... but the issue arises of how we could transfer this policy to new do- mains – for example the in- car do main. In the in- car scenarios the genre of “information seeking” is central. For example the ... in the in- car scenarios. 3.2 Fragmentary Clarifications Another research issue we have been able to explore in con structing this system is the issue of generating fr...

Ngày tải lên: 22/02/2014, 02:20

... bonds between the substrate and these residues, including two bonds formed with the atoms in the backbone and another two bonds formed with side chains of Glu168 and Asn189. Interestingly, they are the ... eight (num- bering in red) of the 11 residues surrounding ATB107 within 5 A ˚ in mIGPS (A) were also included in the 14 residues surrounding sub- strate within 5 A ˚...

Ngày tải lên: 07/03/2014, 03:20

... receptors and with a broad range of other intracellular signaling pathways [21,22]. The purpose of this research is to examine, at the molecular level, whether the human P450c17 overexpressed in HEK-293 ... enzymes in peripheral tissues such as the liver and adipose tissue. Our study aimed at elucidating the nature and the mechanism of the reactions involved in the...

Ngày tải lên: 08/03/2014, 08:20

... defense, the p resent study, together with the previous work described by Concha et al. [8], offers promising evidence that they might. Certainly there is no reason why apolipoproteins in the skin ... nonimmune protein, histone H2A, in catfish skin, where a complex cascade of injury-induced proteases is involved in the regulation of the A MP parasin I production [5]. Ther...

Ngày tải lên: 16/03/2014, 18:20

... activation. These signaling properties of the truncated bikunin indicate that the simultaneous binding of the chondroitin-4-sulfate side chain of bikunin and the N-terminal Kunitz-domain I are required ... Thus, one of the functions of bikunin is the regulation of uPA synthesis and uPA binding by modulat- ing uPAR. It is most likely that the PMA-induced uPAR expression share...

Ngày tải lên: 17/03/2014, 11:20

... background. The putative SAM-binding motif (motif I) is boxed. The positions of the introns are indicated by red lines, and the numbers above indicate the positions of the introns as described in the ... [17]. In B. mori, the BmJHAMT transcript is expressed specifically in CA until the beginning of the final larval instar [9]. In contrast, the BmJHAMT transcrip...

Ngày tải lên: 23/03/2014, 07:20