báo cáo khoa học: "Timing and duration of hatching in gynogenetic, triploid, tetraploid, and hybrid progenies in rainbow trout Edwige QUILLET" pdf

Tài liệu Báo cáo khoa học: "DiMLex: A lexicon of discourse markers for text generation and understanding" docx

... pertain to the two tasks of determining the set of words we regard as discourse markers and thus are to be included in the lexicon, and determining the lex- ical entries for these words. Finding ... detailed studies of individ- ual groups of markers, such as [Vander Linden, Martin 1995] for PURPOSE markers. Besides, the Linguistics literature offers fine-grained analyses of individual markers, ... present in the input specification. Syntagmatic constraints: The constraints regarding the combination of a marker and the neighbouring constituents; most of them are syntactic and appear...

Tài liệu Báo cáo khoa học: Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation pdf

... regulating protein–protein interactions;hydroxyproline provides a docking site for VHL binding while hydroxyasparagine prevents binding of the coacti-vator p300. Finally, the long sought after links ... hydroxylase inhibitor dime-thyloxalylglycine (DMOG), or iron antagonists, when theputative FIH-1 binding region is removed [89]. A regionspanning the FIH-1 binding site in HIF-1a contains anarginine-dileucine ... carboxy-terminal transactivationdomain; CBP, CREB binding protein; CH, cysteine-histidine;CO, carbon monoxide; CREB, cyclic AMP-response element bindingprotein; DMOG, dimethyloxalylglycine; Dsfx,...

Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

... trapped in these proteins. To answer thisquestion, we took advantage of the trypsin-sensitiveregion situated in the linker domain of Abcb1a. Fol-lowing trapping in the absence or presence of Vi and mild-trypsin ... known[5,6]. Mutations in about half of the 48 humanmembers cause diseases and phenotypes includingMDR, and make this family of proteins of great clini-cal interest [7]. Diseases include Tangier ... E552 in NBD1 and E1197 in NBD2. Tofurther characterize the role of these residues in catalysis, we created in Abcb1a the single-site mutants E552D, N and A in NBD1, and E1197D,N and A in NBD2,...

Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebraﬁsh (Danio rerio) pptx

... vari-ety of names, such as ileal lipid-binding protein, intesti-nal 15 kDa protein, ileal bile acid-binding protein and gastrotropin, reﬂecting the speculations of authors onits intracellular ... USAIntracellular lipid-binding proteins (iLBPs) are encodedby a highly conserved multigene family, and includefatty acid-binding proteins (FABP ⁄ Fabps), cellular ret-inol-binding proteins ... according to thetissue from which they were initially isolated, e.g. liver-type fatty acid-binding protein (L-FABP), brain-typefatty acid-binding protein (B-FABP), intestinal-typefatty acid-binding...

Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx

... which points tothe stabilizing effect of this mutation not being realized in the folding TSE, indicative of the loop between theN-terminal b-hairpin and the main a-helix remainingﬂexible in the ... mutation site and immediately ﬂanking residues.Kinetic analysis of ubiquitin foldingThe folding kinetics of WT* have been analysed fromrefolding and unfolding stopped-ﬂow exper iments in GdmCl ... loopconnecting the N-terminal b-hairpin to t he main a-helix. T heproline residues of ubiquitin are passive spectators in thefolding process, but in uence protein stability in a variety of ways.Keywords:...

Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx

... site of action of these two proteins is the rate-limiting step in steroidogenesis [6]. Fatty acyl-CoAs bind to theacyl-CoA-binding protein, which can bind and maythereby activate PBR. This interaction ... acyl-CoA-binding protein known alsoas DBI (diazepam-binding inhibitor) is expressed athigh concentrations in steroidogenic cells [26,27] and interacts with the PBR in the mitochondria [5]. BothDBI and ... participation of MTE-I in theregulation of the rate-limiting step in steroidogenesis.To provide additional insights into the sequentialsteps involved in down-regulation of StAR proteinconcentrations,...

Báo cáo khoa học: A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration doc

... direction of shear stress. In (C), the force is in the direction of tension of actin ﬁlaments, maintained with the help of neighboring cells in contact. In (D), the force is in the direction of pulling ... 2010 FEBSunbinding force of JAM-A–JAM-A interactionsincreases from about 40 to 300 pN with increasingloading rate, whereas the unbinding force of theJAM-A–LFA-1 interaction increases from ... integrin binding at FAs, leading to stretching of talin and activation of vinculin to reinforce the FA (D). The ECs respond to this interactionby forming stress ﬁbers that contract, allowing for...

Báo cáo khoa học: Substrate speciﬁcity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7 Identiﬁcation of a critical aromatic amino acid residue at position 33 doc

... acids, including 55 differences in the ﬁrst 300amino acids of the N-terminus. Both enzymes sharecommon substrates, including HDCA [6]. This led usto compare the N-terminal amino acid sequence of UGT2B4 ... The kinetic parameters of the mutant indica-ted an increase in both Vmax and Kmvalues (Table 1). In the case of UGT2B7, substitution of Y33 to leu-cine led to a severe restriction in aglycones ... N-ter-minal domain of UGTs in substrate speciﬁcity, and many lines of evidence indicated that it may contain themajor structural determinants for substrate recognition.The organization of the UGT1A...

Báo cáo khoa học: Comparative biochemical characterization of nitrile-forming proteins from plants and insects that alter myrosinase-catalysed hydrolysis of glucosinolatesk docx

... anti-ESP serum (A) and by myrosinase assays (B). (L1,ﬂow-through after binding of ESP; W1, wash step after binding of ESP; L2, ﬂow-through after loading of plant extract containingmyrosinase; W2, wash ... protein (341amino acids) with 45–55% amino acid sequence iden-tity to several A. thaliana myrosinase-binding proteins. In the presence of myrosinase, crude extracts of Escherichia coli expressing ... 2006 FEBS of larvae of P. rapae, a protein factor that redirectsthe myrosinase-catalysed hydrolysis of glucosinolates in ingested plant material towards the formation of nitriles instead of toxic...

Báo cáo khoa học nông nghiệp " Effects of Stocking Biomass on Growth, Survival and Production of the Two Sizes of Clam Meretrix lyrata Cultured in the Intertidal Areas And Notes on Hatchery Production of Clam Spat " pot

... biomass gained therefore was reduced accordingly with increasing of stocking biomass although the increase of final production was evident. However, SGR and survival of the treatments T1, T2 and ... difference (p>0.05) in the biomass gained in the treatment T5 and T6 nor percentage of biomass gained in the treatments T7 and T8. In both size groups, the increase in biomass certainly impacted ... significant increased as increasing of stocking biomass (p<0.05). The percentage of biomass gained, in contrast, was reduced as increasing of stocking biomass in T5, T6 and T7 (table 5). However,...

Xem thêm