... upregula-tion of genes involved in extracellular matrix remode-ling (biglycan, matrix gla protein, cathepsins, cystatins,integrin a7 and laminin receptor). These genes are con-sistently upregulated in ... Experimentation Inspectorate of the Danish Ministry of Justice and the investigation con-forms to the Guide for the Care and Use of LaboratoryAnimals published by the US National Institutes of Health(NIH ... mitochondrialratio [5,6] in adaptive hypertrophy. In our study, several genes involved in b-oxidation of lipids (CD36, FACL, fatty acid binding protein)were upregulated. Genes involved in b-oxidation...