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Báo cáo y học: " Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication" ppsx

Báo cáo khoa học: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives pdf

Báo cáo khoa học: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives pdf

... miglitol (2), salacinol (3) and kotalanol (4); (5–7) are derivatives of salacinol with substi-tutions in the ring. (8–9) are ring expanded salacinol derivatives. (10 )and( 11) are miglitol derivatives. ... deriv-atives, against active human recombinant MGAnt. By confirming the higher potency of salacinol and its derivatives against human MGAnt as compared witha-amylase and fungal glucoamylase, our results ... [28].Our previous studies of the inhibitory effect of salac-inol and its derivatives against human a-amylase and fungal glucoamylase, rather than MGA, report theeffectiveness of salacinol to be in...
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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot

... into contact in the absence of ATP, curcumin is then able tobind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding(i.e. inhibiting ... point is the mean ^ SD of three determinations.q FEBS 2001 Inhibition of the Ca2ỵ-ATPase by curcumin (Eur. J. Biochem. 268) 6323 Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively ... possiblyincreased. In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase, thiswas directly measured using [32P ]ATP in the absence of Ca2ỵ(Fig....
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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... 4935 Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor Sandrine Siffroi-Fernandez*, Annie Giraud, Jeanne Lanet and Jean-Louis ... from the association of the V2vasopressin receptor with calnexin (CNX) and calreticulin (CRT), and that of the gonadotropin receptor with thesetwo molecular chaperones and with GRP94 and BiP, which ... France The thyrotropin receptor (TSHR) is a member of the Gprotein-coupled receptor superfamily. It has by now beenclearly established that the maturation of the glycopro-teins synthesized in the...
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Báo cáo y học: "Assessment of the emotional responses produced by exposure to real food, virtual food and photographs of food in patients affected by eating disorders" ppsx

... pro-duced by exposure to real food, virtual food and photographs of food in patients affected by eating disorders Annals of General Psychiatry 2010, 9:30 Gorini et al. Annals of General Psychiatry ... responses produced by exposure to real food, virtual food and photographs of food in patients affected by eating disordersAlessandra Gorini*1, Eric Griez2, Anna Petrova3 and Giuseppe Riva1,4AbstractBackground: ... and healthy controls. The twomain hypotheses of the study were the following: (1) that the virtual exposure elicits emotional responses compara-ble to those produced by the real exposure, and...
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Báo cáo y học: "Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy" pps

... observed in both the synovial lining layer and the synovial sublining layer, these markers were scoredseparately in the two compartments. An overview of the 15 synovial parameters is given in Table ... significantly associated with disease activity in spondyloar-thropathy (SpA) (lining-layer hyperplasia, inflammatory infiltration, polymorphonuclear cells, sublining CD68, and sublining CD163). ... that lining-layerhyperplasia and infiltration with PMNs and macrophage subsets are directly related to the global disease activity in SpA, we next investigated whether synovial histopathologycould...
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Báo cáo y học: " Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication" ppsx

... ancestor of human and yeast (Figure 4). The growth of the mitochondrial proteome by gene duplicationKnowing the homology of proteins with a determined locali-zation in human and yeast, we ... Access2009Szklarczyk and HuynenVolume 10, Issue 11, Article R135Research Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplicationRadek Szklarczyk and Martijn A HuynenAddress: ... the catalytic as well as the RNA processing repertoire by the novel mitochondrial localization of the protein encoded by one of the daughter genes. Evaluation of the phylogenetic distribution of N-terminal...
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Báo cáo y học: "Review of "The Twelfth West Coast Retrovirus Meeting" and "The Twenty-third Annual Symposium on Nonhuman Primate Models for AIDS"" doc

... purposes)AIDS Research and TherapyOpen AccessReviewReview of "The Twelfth West Coast Retrovirus Meeting" and "The Twenty-third Annual Symposium on Nonhuman Primate Models for AIDS"J ... being done inthe field of retrovirology and AIDS. The meetings, "The Twelfth West Coast Retrovirus Meeting"(Palm Springs CA; October 6–8, 2005), and the " ;Twenty-third Annual Symposium ... concluded thatlack of disease progression in these monkeys is a result of the lack of indirect effects of the virus on CD4+ cells.P Bostik (Emory Univ) gave an interesting talk on the lackof...
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Báo cáo y học: "Ulceration of the oral mucosa induced by antidepressant medication: a case report" pps

... lat-eral border of the tongue and the soft palate, althoughother areas of the mouth may also be involved. Manycases of oral cancer are diagnosed during the advancedphase, a fact that results ... basocellularcarcinoma in her face and stomach cancer. Extra -oral clin-ical examination showed facial symmetry and palpable,mobile, smooth and asymptomatic submandibularlymph nodes. A shallow ulcer with an erythematous ... Exfoliativecytology is a viable alternative and should be the comple-mentary examination of choice in these situations.Because an early diagnosis of oral cancer is essential forsurvival and to...
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Báo cáo y học: " Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18" pdf

... 8:22http://www.virologyj.com/content/8/1/22Page 6 of 6 SHOR T REPOR T Open Access Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18Gough G Au1,2*, Leone G Beagley2, Erin S Haley1, Richard D Barry1,2, ... by: Harris RJC.New York: Academic Press; 1964:169-223.doi:10.1186/1743-422X-8-22Cite this article as: Au et al.: Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and ... potential of CVA13,CVA15 and CVA18 was established by using bot hin vitro melanoma cultures, and in vivo melanoma xeno-grafts. The frequency of CVA13, CVA15 and CVA18infections in the community or...
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Báo cáo y học: " Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody" ppsx

... interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody Retrovirology 2010, 7:38 Willett et al. Retrovirology 2010, 7:38http://www.retrovirology.com/content/7/1/38Page ... the virus- receptor interaction may not simply be a modulation of binding affinity, ratherit could represent a shift in the way the Env and receptorinteract. The two modes of interaction may ... mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibodyBrian J Willett*, Martin Kraase, Nicola Logan, Elizabeth L McMonagle, Ayman...
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Báo cáo y học: "Susceptibility of the human retrovirus XMRV to antiretroviral inhibitor" pdf

... to quantify the susceptibility o f XMRV to antiretroviral inhibitors. Our XMRV stocks were derived from two independen tly-iso-lated strains of the virus: XMRV VP62and XMRV 22Rv1. XMRV VP62was ... growing body of evidence suggests that XMRV isintrinsically resistant to many of the drugs used to treatHIV-1 infection, but is sensitive to a small subset of antiretroviral inhibitors. In an ... HIV-1NL4-3were compar-able to the values obtained in other single-cycle drugsensitivity assays [26,59,60].Potential drug-mediated cytotoxicity was assessed bycomparing the number of cells in untreated...
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Báo cáo y học: "Characterization of the human endogenous retrovirus K Gag protein: identification of protease cleavage sites" ppt

... infectivity, wemapped the previously unknown proteolytic cleavage sites of the HERV -K Gag polyprotein.HERV -K virus-like particles based on the HERV -K con-sensus sequence were produced with the help ... is ratherpH3pH10App148 kDa986450361616ZFimyristylationCapsidMatrix P15 NCZnͲFinger(CYNCGQIGHLKKNC) (CPRCKKGKHWASQC)BHERV K Gag Sp1Figure 3 Mapping of HERV -K Gag protease ... the myristoylation orphosphorylation.- A short peptide SP1-HK.- The p15, with a pI of 8.1 and MW of 15.1 kDa.- The slightly over-presented, uncleaved product of SP1-HK and p15 with a pI of...
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Báo cáo y học: "Repolarization of the action potential enabled by Na+ channel deactivation in PSpice simulation of cardiac muscle propagation" ppt

... units because of instability in the PSpice pro-gram, the problem was solved by inserting the BB-2 into the Na+ leg to produce deactivation of the Na+ conduct-ance turned on by the first BB ... Biology and Medical ModellingOpen AccessResearchRepolarization of the action potential enabled by Na+ channel deactivation in PSpice simulation of cardiac muscle propagationLakshminarayanan ... how the duration of the cardiac action potentials (APD50) in the chain of 10 cells can be varied over a wide range by chang-ing the RC time constant. As can be seen, decreasing the delay time...
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Báo cáo y học: " Organization of the pronephric kidney revealed by large-scale gene expression mapping" docx

... enhances our general under-standing of organogenesis in the Xenopus model.DiscussionComplexity of the Xenopus pronephric kidney revealed by large-scale gene expression mapping The pronephric ... counterpart By focusing the large-scale gene expression analysis of the pronephric kidney on slc genes, we have now obtainedunprecedented insights into the diversity and scope of physi-ological ... any expression in the stage 35/36 pronephric kidney. At present, we cannot rule out the possibility that expression of these marker genes occurs only in older, more mature pronephric kidneys....
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Báo cáo y học: "dentification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels" ppt

... report here the identification of several prokaryotic mem-bers of the ART-LGIC superfamily and discuss the general implications of these proteins for the mechanisms and origin of the Cys-loop receptors ... interactions informationOpen Access2004Tasneemet al.Volume 6, Issue 1, Article R4ResearchIdentification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and ... all the animal members of this superfamily. These observationssuggest that the diversification of the prokaryotic forms pre-ceded the emergence of the eukaryotic forms and thus that the root of the...
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