Báo cáo y học: "The SR protein family" pdf

... mRNA Export machinery Export machinery 5′ 3′ 5′ 3′ SR SR SR SR SR ALY/REF ALY/REF SR SR SR ESE m7G SF2/ASF AAAAAAAA mTOR 4EBP P P (a) (b) Pre-mRNA 4EBP eIF4E eIF4E http://genomebiology.com/2009/10/10/242 ... 35 U2AF65 SR protein Py AG U1 snRNP 70K SR protein Exon 1 Exon 2 A U1 snRNP Py U2AF 35 U2AF65 AG 70K U4/U6•U5 tri-snRNP 100K 27K U2 snRNP Exon U2AF 35 U2AF65 SR...

Ngày tải lên: 09/08/2014, 20:20

... Cdc42), Src-family kinases (Src-1, pFyn), the serine/threonine kinase Pak1, the Wiskott-Aldrich syndrome related protein family (NWASP), and the Arp2/3 actin-binding complex. Proteins are shape ... signal-transducing proteins that regulate cyto skeletal reorganization, such as focal adhesion kinase (FAK), the protein tyrosine kinase Fyn, the Rho family of small GTPases, and microtubul...

Ngày tải lên: 09/08/2014, 20:20

... confirmed by microarrays only NAS-17 K03B8.2 Z74039 V:3.16 No PCR product Expression confirmed by microarrays only NAS-18 K03B8.3 Z74039 V:3.16 No PCR product Expression confirmed by microarrays only NAS-19 ... of phy- logeny. Syst. Biol. 51, 673–688. 39. Huelsenbeck, J.P., Ronquist, F., Nielsen, R. & Bollback, J.P. (2001) Bayesian inference of phylogeny and its impact on evolu- tionary biol...

Ngày tải lên: 23/03/2014, 15:21

... vector pGL2- TK (Promega). Yeast two-hybrid and pull-down assays The Clontech yeast two-hybrid system was used according to the manufacturer’s instructions. The prey and bait plasmids used are ... interaction. In this way, it seems likely that proteins such as Eos may be able to bind to CtBP that is already associated with another PXDLS motif-containing protein. For instance, Eos may bind to...

Ngày tải lên: 21/02/2014, 01:21

... *Institute of Biology III, Faculty of Biology, University of Freiburg, Schänzlestrasse 1, D-79104 Freiburg, Germany. † Freiburg Initiative for Systems Biology (FRISYS), University of Freiburg, Schänzlestrasse ... of signaling by the plant hormone cytokinin. AAR-A proteins probably act by competing for phosphorylation with the ARR-B positive regulators of cytokinin signaling - phosphoryl...

Ngày tải lên: 09/08/2014, 20:21

... stricto Chlorophyta (majority of green algae) Mesostigma, Chlorokybus clade Klebsormidiophyceae Zygnematophyceae Coleochaetophyceae Charophyceae - Stoneworts Marchantiophyta - Liverworts Bryophyta - Mosses Anthocerotophyta ... Arabidopsis thaliana; Alyr, Arabidopsis lyrata; Bradi, Brachypodium distachyon; Cpap, Carica papaya; Glyma, Glycine maxima; Mtru, Medicago truncatula; Osat, Oryza sati...

Ngày tải lên: 09/08/2014, 20:21

... activity and inverse agonism in a family C G -protein- coupled receptor. J. Biol. Chem. 275, 29547–29555. 52. Chen, R., Mukhin, Y. V., Garnovskaya, M.N., Thielen, T.E., Iijima, Y. , Huang, C., Raymond, ... Department of Medicinal Chemistry, The Royal Danish School of Pharmacy, Copenhagen, Denmark; 2 Laboratory of Molecular Cardiology, Copenhagen University Hospital, University of Copenhagen...

Ngày tải lên: 08/03/2014, 09:20

... pastoris. Reversible protein phosphorylation catalysed by protein kinases and phosphoprotein phosphatases is a major mechanism utilized by eukaryotic organisms to regulate various cellular processes [1]. Protein ... of other polycations on phosphorylase phosphatase activity of yeast and mamma- lian PP2Ac poly- L -lysine was added to the purified enzymes. As presented in Fig. 5 a peak of...

Ngày tải lên: 08/03/2014, 22:20

... Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark Keywords emerin; Emery–Dreifuss muscular dystrophy; mass spectrometry; phosphorylation; protein kinase A Correspondence J. ... EDMD, cardio- myopathy and Dunnigan-type partial lipodystrophy. J Cell Sci 114, 4435–4445. 6 Tsuchiya Y, Hase A, Ogawa M, Yorifuji H & Arahata K (1999) Distinct regions specify...

Ngày tải lên: 17/03/2014, 17:20

... namely 5.9 for p67phox and 9.1 for p47phox. This is readily explained by the association of these proteins in a complex. As in the preceding fractionations, eluted proteins were analyzed by SDS/PAGE, ... by arrows (insert in the following panels). (A) Chroma- tography of neutrophil cytosol (100 mg protein) on hydroxyapatite. Absorption at 280 nm was recorded. Two sets of eluates, differing by...

Ngày tải lên: 18/03/2014, 01:20