The regulatory content of intergenic DNA shapes genome architecture pptx

... organization of regulatory DNA remain unresolved. We do not know the portion of any genome comprising regulatory DNA. We do not understand the factors that govern the size, distance and orientation of regulatory ... promoter of a gene. Evolution of genome architecture How does this architecture arise? The net difference between the rate of DNA deletion...

Ngày tải lên: 09/08/2014, 20:20

... rather than the size of the genome in which they are found. Evidence for the progressive loss of ancestral genes throughout the evolution of the microsporidian lineage Prior to this study, the ... only 100 ng of sheared DNA. The downside of very short reads (35 bp) was mostly offset by the deep sequence coverage, allowing a detailed analysis of the coding cap...

Ngày tải lên: 09/08/2014, 20:20

... whether the sec- ond Thr is bound to site 2 for catalytic control of TtAK. In order to further clarify the regulatory mech- anism of TtAK by Thr, the crystal structure of full- length TtAK in the ... EC 2.7.2.4) is an enzyme that catalyzes the first committed step, the phosphorylation of the c-carboxyl group of aspartate, of the biosynthetic pathway of the asp...

Ngày tải lên: 18/02/2014, 08:20

... [22]. To genera te the CK2btes ÔantisenseÕ co nstruct, the XhoI fragment of the CK2btes cDNA #421 corresponding to the 12–700 bp region of the sequence of cDNA #911 (one XhoI site in the cDNA #421 is ... gene including the 161 bp of promoter region joined with the first 12 bp of the ORF region was amplified from the DNA of the c osmid clone #9 using the sam...

Ngày tải lên: 21/02/2014, 15:20

... sequences of the Ppp2r5c promoter contain Nrl-binding sites In the search for conserved putative regulatory elements, the sequence of the human Ppp2r5c pro- moter from )300 to )1 relative to the transcriptional start ... that the isolated RNA was suitable for subsequent analyses. Oligo-dT (Intron Biotechnology) was used as the primer in the first step of cDNA synthesis....

Ngày tải lên: 06/03/2014, 02:20

... separately under the Act for regulatory purposes, just as transmission had been treated separately by the FCC for 15 years prior to the pas- sage of the 1996 Act. The language of the definition of both ... behind the back of all other broadband service providers to put them on the same regulatory playing field of the telephone companies ei- ther. That would be...

Ngày tải lên: 07/03/2014, 11:20

... ng/g 24) . These results show that considerable geographical differences exist in the cadmium content of rice. The rice of West Java has been found to have double the cadmium content of rice from ... in the area and analyzed for the element. The cadmium content of the same food item is averaged and multiplied by individual food consumption data or by the national...

Ngày tải lên: 15/03/2014, 23:11

... (a) the hydrolysis of ATP to promote the assembly of the 26S proteasome from the PA700 complex and 20S protea- some; (b) the opening of the channel leading to the 20S proteasome; and (c) the ... behavior of WT a-synuclein in the absence and the presence of PA700. Aliquots of WT a-synuclein assembly reac- tions in the absence (–) or the presence (+) of PA7...

Ngày tải lên: 16/03/2014, 22:20

... complex, the binding of the cofactor at the active site results in the formation of stabilizing hydrogen bonds between the dihydroxypropyl side-chain and the carbonyl oxygen of Ser23 in the autoregulatory ... changes of the pro- tomer resulting in a displacement of the cofactor bound at the active site by 2.6 A ˚ (mean distance) in the direction of the iron...

Ngày tải lên: 17/03/2014, 09:20

... during the crisis. 11 Table 2 summarizes the main results of the regressions, the complete set of results is provided in the appendix. The results show that the information content of the RBNZ’s ... crisis, the information content of interest rate projections relative to the no-change prediction of a random walk has increased further. According to Table 1, t...

Ngày tải lên: 22/03/2014, 23:20