The principles of toxicology environmental and industrial applications 2nd edition phần 9 pdf
The principles of toxicology environmental and industrial applications 2nd edition phần 9 pdf
... concerned. The determination of fitness for a given job should be based on the assessment of the health of the worker and on a good knowledge of the job demands and the worksite. The workers ... implement the full measures and intent of the program, it will not work. The worker is the focus of the entire program and is also involved in the process. Employees areobligated to themselves and their ... 18.0TABLE 20.3. Percent Distribution of Reported Occupational Illnesses by Category of Illness, PrivateIndustry, 198 2– 199 8Category 198 2 198 6 199 0 199 4 199 8Total illness cases 100 100 100 100...
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The principles of toxicology environmental and industrial applications 2nd edition phần 1 ppt
... µg/day of PCP is the SHD, which when divided by the water ingestion rate of 2 L/day of water becomes 174 µg/L.)]If the route of environmental exposure to PCP were via the ingestion of food, then the ... References and Suggested Reading 168 9 Pulmonotoxicity: Toxic Effects in the Lung 1 69 Cham E. Dallas 9. 1 Lung Anatomy and Physiology 1 69 9.2 Mechanisms of Industrially Related Pulmonary Diseases 181 9. 3 ... Sullivan and G. R. Krieger, eds., Williams & Wilkins, Baltimore, 199 2, pp. 9 23.Beck, B. D., E. J. Calabrese, and P. D. Anderson, “ The use of toxicology in the regulatory process,” in Principles and...
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The principles of toxicology environmental and industrial applications 2nd edition phần 2 ppt
... location of esterases is in the blood (plasma and erythrocytes), and of great concern is the enzyme normallyresponsible for the hydrolysis of acetylcholine. Blockade of this enzyme is the mode of ... TOXICITY OF THE BLOODbetween liver and intestine is also included in the model. These features of the model are choices madeby the model developer, and reflect the known physicochemical behavior of ... Whether the increased rate of bile flow will increase the rate of elimination of a compound that is both metabolized and excretedby the liver depends on whether the rate-limiting step is the...
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The principles of toxicology environmental and industrial applications 2nd edition phần 3 pps
... made of the concentration of PAH per milliliter of plasma(PPAH), of the concentration of PAH per milliliter of urine (UPAH), and of the volume of urine excretedper minute (V). Using the ... hydrophilicsubstances is reduced. Often the skin of lab animals is covered with plastic wrap to enhance the hydration of the skin and increase the rate of uptake of agents applied to the surface of the skin. Forcompounds ... reabsorbed in the last portion of the nephron, so that a total of 99 percent of the fluid filtered at the glomerulus is reabsorbed—only 1 percent of the fluid entering the nephron is excreted in the urine....
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The principles of toxicology environmental and industrial applications 2nd edition phần 4 ppsx
... mucosal barriers, and the unique activity of 1 89 Principles of Toxicology: Environmental and Industrial Applications, Second Edition , Edited by Phillip L. Williams, Robert C. James, and Stephen M. ... oviductal and uterine motility and immobilization of the cilia lining the oviduct. The pertinence of these observations to human exposures and the observed effects of smoking are not clear.However, the ... Understanding the underlying mechanisms will help make sense out of the more complex, and less understood issues in female and developmental toxicology. As interest2 09 Principles of Toxicology: Environmental...
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The principles of toxicology environmental and industrial applications 2nd edition phần 5 ppsx
... attached microtubules to the very center of the cell, lining up in the equatorial plane of the mitotic spindle. With still further growth of the spindle, the chromatids in each pair of chromosomes are ... test with the dissection technique detects the germ cellmutagenicity of acrylamide in rat meiotic cells,” Mutat. Res. 3 09( 2): 255 ( 199 4).Tarcher, A. B., ed., Principles and Practice of Environmental ... 2/6 33 20/ 29 69 In vivo cytogenetics 8 /9 89 9/15 60 0/0 — 11/12 92 In vitro SCE 100/101 99 31/44 70 0/10 0 13/ 29 45In vivo SCE 21/21 100 10/15 67 0/0 — 5/12 42UDS in hepatocytes 19/ 22 86 6/30...
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The principles of toxicology environmental and industrial applications 2nd edition phần 6 pps
... discussed the fundamental concepts of metal toxicity. Because of the largenumber of metals, their ubiquitous nature, and their chemical and physical diversity, the field of metal toxicology is one of ... Values and Biological Exposure Indices, 6th ed., 199 1– 199 8.ATSDR (Agency for Toxic Substances and Disease Registry), Toxicological Profiles, Atlanta, GA, 199 3– 199 9.Chang, L. W., L. Magos, and ... ACS.As awareness of environmental contamination and the ubiquity of synthetic chemicals arose in the 196 0s, specifically after the release of Rachel Carson’s Silent Spring in 196 2, speculation...
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The principles of toxicology environmental and industrial applications 2nd edition phần 7 pptx
... MaterialsCompound CAS No. 199 9ACGIHTLVa(ppm) 199 9ACGIHSTELb(ppm) 199 9ACGIHCarcinogen Class 199 9OSHA-PEL (ppm) 199 9OSHA-STEL(ppm) 199 9USEPACarcinogen ClassdAcetaldehyde 75-07-0 NE 25 A3 ... effective anesthetics, and thisproperty increases with the molecular size. The utility of this property is, however, limited by the irritanteffects of ethers, and the fact that they are easily ... 2.72 0 .98 Styrene 100-42-5 C6H5(C2H4) 104.2 –23 293 5 310 3.6 0 .91 Tetrahydrofuran 1 09- 99- 9 C4H8O 72.1 –163 150 131 Miscible 2.5 0. 89 Toluene 108-88-3 C6H5CH3 92 .1 –1 39 232...
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The principles of toxicology environmental and industrial applications 2nd edition phần 8 pot
... justified by the data, and are they consistentwith the current scientific understanding of the test or area of toxicology? •Is the outcome of the reported experiment dependent on the test conditions, ... addition, that is, if they lie above and to the right of the dose-addition line, a synergistic effect can be inferred. On the other hand, responses below the line and to the left indicate antagonism.From ... sound, certain other characteristics of the experimental animals can influencetoxic responses, and therefore the extrapolation of these responses to humans. Examples include the age of the animal...
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The principles of toxicology environmental and industrial applications 2nd edition phần 10 pptx
... studies of, 197 - 199 clinical detection of, 195 5 197 immune reactions and disorders: allergic reactions, 194 autoimmunity, 195 immunosuppression, 194 4 195 immune response, biology of, 1 89 194 multiple-chemical ... development, and sexual maturation; and effects on the motherconcern lactation and acceptance of the offspring.resorption The loss of substance in the mucous lining of the uterus.reticuloendothelial ... involving the interaction between the nervous system and the hormones of the endocrine glands.neurofibril One of the delicate threads running in every direction through the cytoplasm of the bodyof...
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