The principles of toxicology environmental and industrial applications 2nd edition phần 3 pps
The principles of toxicology environmental and industrial applications 2nd edition phần 3 pps
... hydrophilic
substances is reduced. Often the skin of lab animals is covered with plastic wrap to enhance the
hydration of the skin and increase the rate of uptake of agents applied to the surface of the skin. For
compounds ... permeability and chemical composition of the irritant
determine the rate of percutaneous penetration and how much chemical reaches...
The principles of toxicology environmental and industrial applications 2nd edition phần 4 ppsx
... oviductal and uterine motility and immobilization of the cilia lining the oviduct. The
pertinence of these observations to human exposures and the observed effects of smoking are not clear.
However, the ... mucosal barriers, and the unique activity of
189
Principles of Toxicology: Environmental and Industrial Applications, Second Edition
, Edited by P...
The principles of toxicology environmental and industrial applications 2nd edition phần 5 ppsx
... attached microtubules to the very center of the
cell, lining up in the equatorial plane of the mitotic spindle. With still further growth of the spindle,
the chromatids in each pair of chromosomes are ... 4 or 4
3
). The 20 amino acids and three terminal
codes account for less than half of the available codons, leaving well over 30 codons of the possible
64....
The principles of toxicology environmental and industrial applications 2nd edition phần 6 pps
... discussed the fundamental concepts of metal toxicity. Because of the large
number of metals, their ubiquitous nature, and their chemical and physical diversity, the field of metal
toxicology is one of ...
Casarett and Doull’s Toxicology: The Basic Science of Poisons
, 5th ed., 1996.
14.7 SUMMARY
34 3
13. 9 CANCER AND OUR ENVIRONMENT
30 5
TABLE 13. 13 Agent...
The principles of toxicology environmental and industrial applications 2nd edition phần 1 ppt
... µg/day of PCP is the SHD, which when divided by
the water ingestion rate of 2 L/day of water becomes 174 µg/L.)]
If the route of environmental exposure to PCP were via the ingestion of food, then the ... ____________
1 .3 THE IMPORTANCE OF DOSE AND THE DOSE–RESPONSE RELATIONSHIP
9
where MW is the molecular weight of the chemical (g/mol) and 24.5 is th...
The principles of toxicology environmental and industrial applications 2nd edition phần 2 ppt
... location of
esterases is in the blood (plasma and erythrocytes), and of great concern is the enzyme normally
responsible for the hydrolysis of acetylcholine. Blockade of this enzyme is the mode of ... Whether the increased rate
of bile flow will increase the rate of elimination of a compound that is both metabolized and excreted
by the liver depends on whet...
The principles of toxicology environmental and industrial applications 2nd edition phần 7 pptx
... 56- 23- 5 CCl
4
1 53. 8 –9 170 91 7 93 5 .32 1.59
Chloroform 67-66 -3 CHCl
3
119.4 –82 1 43 160 7,920 4.12 1.48
Methyl bromide 74- 83- 9 CH
3
Br 95.0 – 137 38 1,444 900 3. 36 1. 73
Methyl chloride 74-87 -3 ... C
6
H
5
(C
2
H
4
) 104.2 – 23 2 93 5 31 0 3. 6 0.91
Tetrahydrofuran 109-99-9 C
4
H
8
O 72.1 –1 63 150 131 Miscible 2.5 0.89
Toluene 108-88 -3 C
6
H
5
CH
3
92.1 –...
The principles of toxicology environmental and industrial applications 2nd edition phần 8 pot
... justified by the data, and are they consistent
with the current scientific understanding of the test or area of toxicology?
•
Is the outcome of the reported experiment dependent on the test conditions, ... addition, that is, if they lie above and to the right of the
dose-addition line, a synergistic effect can be inferred. On the other hand, responses below th...
The principles of toxicology environmental and industrial applications 2nd edition phần 9 pdf
... concerned. The determination
of fitness for a given job should be based on the assessment of the health of the worker and
on a good knowledge of the job demands and the worksite. The workers ... implement the full measures and intent of the program, it will not work.
The worker is the focus of the entire program and is also involved in the process...
The principles of toxicology environmental and industrial applications 2nd edition phần 10 pptx
... toxicity, 39 5 -39 7
health care facilities case study of, 545-546
herbicides, 35 6
metals pharmacokinetics, 32 8 -32 9
arsenic, 33 6
beryllium, 33 7 -33 8
cadmium, 33 8 -33 9
chromium compounds, 33 9 -34 0 ... health and 508
Ingestion:
herbicides, 35 6
metals ingestion, 32 9
arsenic, 33 6
cadmium exposure, 33 8 -33 9
lead poisoning, 34 0 -34 1
mercury toxicology...