Handbook of clinical drug data - part 2 pps
Handbook of clinical drug data - part 2 pps
... 20 0, 400 mg PO 20 0–400 mg q PO (6 mo– 12 yr) Cl cr 10–49 mL/min: 6.8 25 Carbacephem analogue Lorabid Susp 20 , 40 12 24 hr. 7.5–15 mg 50% of usual (PO 20 0 of cefaclor with similar mg/mL. q 12 ... Parenteral induction: (Cl cr 50–69 mL/min) 2. 5 mg/kg q 12 hr; (Cl cr 25 –49 mL/min) 2. 5 mg/kg q 24 hr; (Cl cr < ;25 mL/min) 1 .25 mg/kg q 24 hr; (hemodialysis) 1 .25 mg/kg 3...
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Handbook of clinical drug data - part 3 ppsx
... dose of about 15 units/m 2 , serum levels of 10–1000 milliunits/L are obtained. 21 2 Steady-state levels during continuous infu- sion of 20 units/day are 50 20 0 milliunits/L. 21 5 V d‚ is 0 .27 ± ... Alfa-2a and 2b are 100% bioavailable after IM or SC administration, with an absorption half-life of about 6 hr. IM or SC INTERFERON ALFA: ALFA-2A Pegasys, Roferon-A ALFA-2B Intron A...
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Handbook of clinical drug data - part 9 pps
... considerations. Pediatr Drugs 20 00 ;2: 223 –8. D RUGS AND B REASTFEEDING 937 ch 12. qxd 8/13 /20 01 3:11 PM Page 937 Geriatric Drug Therapy Dianne E. Tobias Geriatric drug therapy is an important area of therapeutics ... Antipsychotics and breast-feeding. A review of the literature. Paediatr Drugs 20 00 ;2: 23–8. 106. Yoshida K et al. Neuroleptic drugs in breast-milk: a study of...
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Handbook of clinical drug data - part 4 pptx
... 60, 90, 120 mg; SR Cap ( 12 hr; Cardizem SR, various) 60, 90, 120 mg; SR Cap (24 hr; Cardizem CD) 120 , 180, 24 0, 300 mg; (24 hr; Di- lacor XR) 120 , 180, 24 0 mg; (24 hr; Tiazac) 120 , 180, 24 0, 300, ... only 22 ± 8% is bioavailable be- cause of extensive first-pass elimination; bioavailability increases in liver disease. 25 1 Covera-HS provides a 4- to 5-hr delay before releasi...
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Handbook of clinical drug data - part 5 ppt
... (C-IV) Tab 20 , 40 mg. 60–160 mg/day 1–3 > ;24 Paxipam SHORT-ACTING HYPNOTICS Midazolam e (C-IV) Inj 1, 5 mg/mL — — 1.5–3 Versed Syrup 2 mg/mL. Triazolam (C-IV) Tab 0. 125 , 0 .25 mg. 0. 125 –0 .25 ... mg/day c 0.7–1.6 11 21 Xanax 1, 2 mg 5–10 mg/day d Various Soln 0.1, 1 mg/mL. Lorazepam e (C-IV) Tab 0.5, 1, 2 mg 2 10 mg/day 2 10 20 Ativan Soln 2 mg/mL Various Inj 2, 4 mg/m...
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Handbook of clinical drug data - part 6 pdf
... containing Capsule con- Capsule con- Rectal suspen- coated pH mesalamine prodrug taining 5- taining ethyl- sion, sup- dependent cleaved by colonic ASA dia- cellulose- pository. (pH 7), de- bacterial azoreductases. ... Selectivity of 5-HT 3 receptor antagonists and anti-emetic mechanisms of action. Anticancer Drugs 19 92; 3:79–85. 88. Holdsworth MT et al. Assessment of chemotherapy-in...
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Handbook of clinical drug data - part 7 ppt
... –174. 704 ch08.qxd 8/13 /20 01 2: 24 PM Page 704 32. J. Patten SB, Neutel CI. Corticosteroid-induced adverse psychiatric effects: incidence, diagnosis and manage- ment. Drug Saf 20 00 ;22 :111 22 . 33. Callahan ... 8/13 /20 01 2: 24 PM Page 693 protein bound to albumin; 83% of a dose is present in serum as the parent drug and conjugated medroxyprogesterone; it is hydroxylated to 6-...
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Handbook of clinical drug data - part 8 pptx
... series. 66 Nitrofurantoin HA In G-6-PD deficiency; also encountered with enolase deficiency (mechanism un- known). 4 822 D RUG -I NDUCED D ISEASES (continued ) ch11.qxd 8/13 /20 01 2: 55 PM Page 822 • Drug- Induced ... 1946 ;21 2 :21 1 24 . 81. Ascensao JL et al. Quinidine-induced neutropenia: report of a case with drug- dependent inhibition of granulo- cyte colony generation. Acta H...
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Handbook of clinical drug data - part 10 doc
... units/L (AST, SGOT) Adult 8 20 8 20 >60 yr, M 11 26 11 26 >60 yr, F 10 20 10 20 Bicarbonate (S) mEq/L mmol/L Arterial 21 28 21 28 Venous 22 29 22 29 (WB, art) Adult 18 23 18 23 Bilirubin (S) mg/dL ... assessment, 1 029 –1030 ANTIALLERGICS, pregnancy, 897 ANTI-ANDROGENS, 24 5 24 6 ANTIARRHYTHMIC DRUGS, 29 7– 321 , 322 – 323 breastfeeding, 922 – 923 pregnancy, 887 ANTIASTHM...
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