Báo cáo y học: "Microparticles as biomarkers in autoimmunity: from dust bin to center stage" potx

... disease activity, it is nevertheless important in putting MPs center stage as disease markers and showing how the components in the blood can be mined in new and intriguing ways. Competing interests The ... that an increase in the level of secretory phospho- lipase A 2 could lead particle destruction via enzymatic diges- tion of membrane lipids. In that case, secretory phospholi...

Ngày tải lên: 09/08/2014, 14:22

... remodeling is, however, dynamic, altering in character as the disease process develops. Collagen metabolism is largely regulated by proteases, particularly a class of enzymes referred to as the matrix ... might initiate a sustained inflammatory response, associated with ongoing collagen metabolism, thereby underlying the poor long-term outcome in adult survivors [7]. While an in- h...

Ngày tải lên: 13/08/2014, 16:20

... the moment.“ “Casualties were, in some cases, transferred from the earthquake area to a specific city, and because of the inability to admit the casualties, they were referred to yet a second city“ according ... Prehospital Disast Medicine 2008, 23(3):263-268. 34. Kondo H, Koido Y, Morino K, Homma M, Otomo Y, Yamamoto Y, Henmi H: Establishing Disaster Medical Assistance Teams in...

Ngày tải lên: 25/10/2012, 09:56

... version 4.0) was used in this study [9]. Severity of a total of 24 symp- toms, grouped in 6 different domains, was evaluated using a 7-point rating scale ranging from 'not present' to 'extremely ... behaviours (Total Negative Factors). The Total Patient Asset score was obtained by the sum of the positive factors minus the sum of negative fac- tors and adding 150 as a...

Ngày tải lên: 08/08/2014, 21:20

... histidine-rich glycoprotein; IGFBP-4: insulin-like growth factor-binding protein 4; IHRP: inter-alpha-trypsin inhibitor family heavy chain-related protein; IPI: international Protein Index; ITIH4: inter-alpha-trypsin ... these proteins, including serum amy loid A (SAA), apolipopro- tein A-I V (ApoA4), antithro mbin III (synonymous with SERPINC1), and inter-alpha-trypsin inhibitor heavy chain...

Ngày tải lên: 10/08/2014, 21:23

... article as: Joya et al.: Acute heroin intoxication in a baby chronically exposed to cocaine and heroin: a case report. Journal of Medical Case Reports 2011 5:288. Submit your next manuscript to BioMed ... ctively highlighted by test- ing in two different biological matrices accounting for different time windows of exposure [10]. In Spain, heroin and cocaine are usually consumed tog...

Ngày tải lên: 10/08/2014, 23:21

... fibrosis [56]. Proinflammatory cytokines in urinary obstruction TNF-α and IL-1 The prototypical pro-inflammatory cytokines, TNF-α and interleukin-1 (IL-1), play a major role in the recruit- ment of inflammatory ... alpha-smooth muscle actin (a marker of myofibroblasts) [59]. Other proinflammatory cytokines Macrophage migratory inhibitory factor (MIF) is a proin- flammatory cytokine which...

Ngày tải lên: 11/08/2014, 03:20

... proinflammatory cytokines Macrophage migratory inhibitory factor (MIF) is a proin- flammatory cytokine which regulates leukocyte activa- tion and fibroblast proliferation but although it is increased in the ... (Figure 1). In relation to the inflammatory process, Ang II type 1 receptor (AT1R) regulates several proinflammatory genes, including cytokines (interleukin-6 [IL-6]), chemokines...

Ngày tải lên: 11/08/2014, 06:22

... lower abdominal pain and distension associated with the inability to pass urine. A detailed clinical history revealed no history of any urological, neurological or sexually transmitted disease. He ... AUR is defined as an emergency situation characterized by a sudden inabil ity to pass urine and is associated with l ower abdominal pain and distention [1]. The aetiology of AUR in young...

Ngày tải lên: 11/08/2014, 17:21

... of inducible nitric oxide synthase (iNOS), myeloperoxidase (MPO), nitrotyrosine and 4-hydroxy-2-nonenal (4-HNE) were analysed from cytospins by immunocytochemistry. Eosinophil cationic protein ... secondary antibody was used (Dako Cytomation, Glostrup, Denmark). For immunostaining, Zymed ABC Histostain-Plus Kit (Zymed Laboratories Inc.) was used according to the manufacturer's protoc...

Ngày tải lên: 12/08/2014, 16:20