Báo cáo y học: " Heterogeneity of human effector CD4+ T cells" doc

... argue against such a possibility. Role of T- helper type 1 and T- helper type 17 cells in pathogenicity The demonstration of a potential plasticity of human Th17 cells to Th1 cells [61] was of great importance ... Moreover, the potential plasticity of Th17 to Th1 cells, but not of Th1 to Th17 cells, has been reported [78]. These findings support the substantial developmental p...

Ngày tải lên: 09/08/2014, 14:22

... mutation in the gene of GLP-1 (7-37) in the present study. This mutation resulted in the substitution of glycolamine for alanine at the se- cond site of GLP-1 (7-37) peptide. Study has reported ... These characteristics facilitate the filtration of GLP-1 through kidney [15]. Although structural modifica- tion of GLP-1 may overcome degradation by dipep- tidyl peptidase IV, this d...

Ngày tải lên: 25/10/2012, 11:10

... evident to the quite effect of loading process on erythrocytes and/or protective effect of pravastatin as investigated in previous study stated that the pravastatin protect erythrocytes against ... Osmotic fragility behavior of pravastatin loaded eryth- rocytes Osmotic fragility determines the susceptibility of erythrocytes to osmotic lysis in respect to serial dilu- tion of N...

Ngày tải lên: 25/10/2012, 11:10

... representation from three different views, rotated by 120 degrees against each other. Orientation of the peptide is N-terminal to the top. Positive and negative electrostatic potentials are indicated ... proteins that are reported to directly interact with Vpr may form hydrophobic environ- ments for Vpr interaction. In this respect, among the solvent conditions used for the present study, th...

Ngày tải lên: 24/03/2014, 04:21

... induce tumor-specific apoptosis and to share the structural and functional char- acteristics with the proteins of TNF family. Recently, the crystal structure of human TRAIL showed that TRAIL is ... the TNF family proteins, a variety of proteins at acidic pH have been demonstrated to form the MG-like state retaining their partial secondary structures but lacking complete tertiary struc...

Ngày tải lên: 31/03/2014, 08:20

... memory T cells might favor the recruitment of Th1-type effector memory T cells into granulomatous lesions of the respiratory tract, whereas in generalized WG the CCR3-mediated recruitment of Th2-type ... receptor expres- sion might contribute to the recruitment of distinct effector memory T cell populations into granulomatous lesions, resulting in different cytokine patterns...

Ngày tải lên: 09/08/2014, 01:21

... inconsistent results. The majority of published studies evaluated the responses of the autonomic nervous system to physical stressful situations. This approach was used to test stress-reactivity as ... Turk 2 1 Department of Neuropsychology at the University of Heidelberg, Central Institute of Mental Health, J5, 68169 Mannheim, Germany 2 Department of Anesthesiology at the Univers...

Ngày tải lên: 09/08/2014, 07:20

... diversity of autoanti- bodies was also high, as indicated by the detection of autoan- tibodies to 19 of the 21 (90%) autoantigens tested. The most common autoantibody, present in 31% (31 patients), ... 1990, 144:1737-1743. 16. Targoff IN, Trieu EP, Miller FW: Reaction of anti-OJ autoantibod- ies with components of the multi-enzyme complex of aminoa- cyl-tRNA synthetases in additio...

Ngày tải lên: 09/08/2014, 10:20

... cdk9/cyclin T1 [15-17]. Tat associates with cdk9 [16,17] through interaction with cyclin T1 which interacts with the TAR RNA loop structure [15]. Tat interacts with human cyclin T1 through a critical cysteine ... almost com- pletely inhibited virus replication at day 12 and inhibited replic ation by approximately 50% at day 18 in two inde- pendent experiments. It is important to note th...

Ngày tải lên: 10/08/2014, 05:21

... of the requirement for two aspartate residues that are at the dimer inter- face,itisbelievedthatproteaseprecursordimerization is essential for formation of the catalytic site to initiate protease ... growth and infectivity [28]. Collectively, these data suggest that TFR mainly serves as a linker between the frameshift site and the mature protease. Consistent with this role, the TFR polype...

Ngày tải lên: 10/08/2014, 05:21