Báo cáo y học: "Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis" doc
Báo cáo y học: "Diagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritis" doc
... assay; CCP3: cyclic citrullinated third-generation peptide assay; CFFCP1: chimeric fibrin/filaggrin citrullinated peptides 1; CFFCP2: synthetic chimeric fibrin/filaggrin peptides 2; CFFCP3: synthetic ... purposes)Vol 11 No 5Research articleDiagnostic and prognostic value of antibodies against chimeric fibrin/filaggrin citrullinated synthetic peptides in rheumatoid arthritisRaimon Sanmartí1, Eduard ... factor.Figure 1Titers of autoantibodies against the chimeric citrullinated fibrin/filaggrin peptides anti-CFFCP1, anti-CFFCP2, anti-CFFCP3, and against cyclic cit-rullinated peptide CCP2 in RA and control...
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Báo cáo y học: "Expression and functional properties of antibodies to tissue inhibitors of metalloproteinases (TIMPs) in rheumatoid arthritis" docx
... typically induced by externalstimuli such as certain inflammatory cytokines (IL-6, IL-1β) and by certain growth factors.Extracellularly, TIMPs inhibit MMP activity by forming high-affinity ... MMPs. The amino-termi-nal domain of TIMP binds the active site of MMPs, inhibitingtheir proteolytic activity. The carboxy-terminal domain of cer-tain TIMPs has also the ability to form complexes ... weight22 kDa corresponding to TIMP-2 forming a band in the blot-ting membrane.Relation of TIMP antibodies to clinical features of RA Antibodies against TIMPs in blood and/ or synovial fluid sam-ples...
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Báo cáo y học: "Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study" ppt
... and distinct subsets of patients are characterized by the presence of autoantibod-ies such a rheumatoid factor and anti -citrullinated protein antibodies, we also performed a stratified analysis ... Immunol Lett 2008, 118:1-5.31. Spolski R, Leonard WJ: The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer [review]. Curr Opin Immunol2008, 20:295-301. ... LA, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, GregersenPK: A missense single-nucleotide polymorphism in a geneencoding a protein tyrosine phosphatase (PTPN22) is associ-ated with rheumatoid...
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Báo cáo y học: "The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue" doc
... synovial sublining by macro-phages, lymphocytes, and other immune cells, and by intimallining layer hyperplasia due to increased numbers of intimalmacrophages and fibroblast-like synoviocytes (FLS) ... staining of rheumatoid arthritis synovial tissue with antibodies against RasGRF1 and cell-specific markersRepresentative double staining of rheumatoid arthritis synovial tissue with antibodies against ... MMP-1 in the RA synovial sublining, butnot in the intimal lining layer (Figure 7b). Instead, a positive cor-relation between RasGRF1 and MMP-3 expression wasobserved in the intimal lining layer...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
... pharmacy data. While clinical disease activity measures remain the gold standard for assessing effectiveness in RA, the many large administrative data sources in the U.S. and internationally are ... written informed consent. VARA contains demographic, clinical and RA-specific information including disease activity scores (DAS), as assessed by physicians using the DAS28 [23] and the Clinical ... (methotrexate; sulfasalazine; leflunomide; hydroxychloroquine) that they had not been already receiving in the 6 months prior to the index date Increase in biologic dose or frequency prohibited •...
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Báo cáo y học: " Induction and effector phase of allergic lung inflammation is independent of CCL21/CCL19 and LT-beta
... cascade of cytokines and chemokines necessary for tissue eosinophilia without involvement of draining lymphoid tissues. We studied the induction of lung allergic in- flammation in mice lacking ... the last intranasal challenge. Briefly, mice were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) capable of meas-uring changes in airflow and trans-thoracic pressures and resistances ... the cytokines IL-4 and IL-13, which in turn induced epithelial production of the eosinophil chemokine eotaxin [28]. Since local Th2 cell produc-tion of cytokines has also been implicated in...
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Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx
... betweenthese peptides and cysteine-free peptides recently described in the venom of spiders and insects.Parabutoporin and opistoporin 1 were synthesizedchemically and preliminary studies on ... pandinin 1 contains only one charged aminoacid in this fragment. Parameters that might in uenceantibacterial activity that differ between opistoporin 1 and pandinin 1 are the hydrophobicity ... hydrophobicity (pandinin 1–0.1214,opistoporin 1–0.1652) and the hydrophobic moment, whichis nearly double for pandinin 1 (pandinin 1 0.1071,opistoporin 1 0.055). The amino acid substitutions highlyresponsible...
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Tài liệu Báo cáo Y học: Structural and biochemical characterization of neuronal calretinin domain I– II (residues 1– 100) Comparison to homologous calbindin D28k domain I–II (residues 1 –93) pdf
... full-length proteins.Keywords: calretinin; calcium; calbindin D28k; EF-hand;NMR secondary structure.Calretinin (CR) and calbindin D28k(Calb) are homologouscalcium-binding EF-hand proteins with ... (B)45Ca-overlay of the blot shown in part A indicating that CR and GSTfusion products of CR fragments bind45Ca.Fig. 6. ‘Glycine 6’ of the calcium-binding loopis a sensitive indicator of calcium loading. ... Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology, Warsaw, Poland;2Department of Biochemistry and Molecular Biology, University of Debrecen, Hungary;3Department of Inorganic...
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Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx
... dimerization in helix IV (Figs 3 and 5). The binding of Ca2+to calhepatin increases itsintrinsic fluorescence intensity and kmax. This result, thedecrease in the protein hydrodynamic volume, and ... by the increase in its intrinsicfluorescence intensity and kmax, the decrease in theapo-calhepatin hydrodynamic volume, and the Ca2+-dependent binding of the protein to phenyl-Superose. Likemost ... 7.4).45Ca2+binding was determined by the method of Mani and Kay[77]using15lMapo-(lungfish calhepatin) as describedby Dell’Angelica et al. [10]. Binding data were analyzed bynonlinear regression...
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Báo cáo Y học: Expression and purification of the recombinant subunits of toluene/ o-xylene monooxygenase and reconstitution of the active complex potx
... functional.To identify the hydroxylase component of the complexwe performed single-turnover assays, in the absence of theTomo F subunit, by measuring the ability of Tomo H,Tomo C and Tomo D, in each possible ... mass of about 10, 38 and 57 kDa, theexpected molecular size of recombinant subunits B, E and A, respectively. The identity of the proteins was furtherchecked by N-terminal sequencing of the ... afinal volume of 200 lL. Anaerobiosis was established byrepeated cycles of flushing and filling with nitrogen. Fullyreduced proteins were obtained by the addition of sodiumdithionite in a 10-fold...
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Từ khóa: diagnostic and prognostic value of procalcitonin in communityacquired pneumoniabáo cáo y họcdiagnostic and prognostic valuebáo cáo y họcintestinal pneumatosis in adults diagnostic and prognostic valuebáo cáo y học cổ truyềnBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam