Báo cáo y học: "Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis" docx

... 4 Concentration of inflammatory cytokines in serum of mice with GPI -induced arthritisConcentration of inflammatory cytokines in serum of mice with GPI- induced arthritis. After immunization with glucose-6-phosphate ... factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase...

Ngày tải lên: 09/08/2014, 10:23

... isotype, in comparison with individuals not having any of the factors or having any one of them separately. In particular, the com- bination of SE gene carriage and the presence of anti-CCP antibodies ... conversion of arginine to citrulline in HLA- DRB1* 040 1 transgenic mice has been demonstrated to significantly increase activation of CD4 + T cells [6]. In...

Ngày tải lên: 09/08/2014, 01:23

... determined. To determine the loss of toluidine blue staining from the section, the auto-select tool was used to designate and create a line at the point that the loss of staining ended; using the ... then exported into Cytospec Software for Infrared Spectral Imaging (Cytospec, Inc, http://www.cytospec.com/ , Berlin, Germany) and a 'quality test' was performed to remove...

Ngày tải lên: 09/08/2014, 06:23

... Res Toxicol. 20 04; 17: 197-207. 44 . Martini M, Termini J. Peroxy radical oxidation of thymidine. Chem Res Toxicol. 1997; 10: 2 34- 41. 45 . Pandey KB, Mehdi MM, Maurya PK, et al. Plasma protein ... activity and cellu- lar toxicity is beyond controversial. Toxic effects like killing of eukaryotic and prokaryotic cells, stably transfected with different fluorescent proteins (...

Ngày tải lên: 25/10/2012, 11:15

... behavior of LMVs composed of dimyristoylglycerophosphocholine (Myr 2 Gro-PCho), dimy- ristoylglycerophosphoethanolamine (Myr 2 Gro-PEtn) and dimyristoylglycerophosphoglycerol (Myr 2 Gro-PGro) by DSC, ... readily incorporate into Myr 2 Gro-PGro bilayers in the liquid-crystalline state and remain incorporated in the gel state. Permeabilization of phospholipid bilayers by GS ring-s...

Ngày tải lên: 21/02/2014, 01:21

... organiza- tion. Adenylate-sensitivity of pH effects POR, in common with many NADPH-binding enzymes, contains the characteristic motif Gly-X-X-X-Gly-X-Gly associated with the bA-aA-bB binding domain known as the ... the restoration of the pH to pH 7.5, relatively little PChlide 653 is formed indica- ting the ability of NADPH to stabilize the enzyme. The NADPH binding properti...

Ngày tải lên: 22/02/2014, 04:20

... is incorporated into cellular glycerophospholipids by a distinct pathway. Free AA is initially converted to AA-CoA by AA-CoA synthe- tase (a) [46 ]. Inhibitors of AA-CoA synthetase prevent AA incorporation ... synthetase, inhibition of CoA-IT results in an increase in free AA and a corresponding build-up of AA in triacylglycerols that can be prevented by co-incubation of cel...

Ngày tải lên: 22/02/2014, 07:20

... terminated. The lung tissues were embedded in paraffin wax, stained with hematoxylin and eosin, and examined under a light microscope. The lung injury was scored according to inflammatory changes, ... Severity of Endotoxin -Induced Acute Lung Injury. J Immunol 2006, 176 :49 95-5005. 6. Nishina K, Mikawa K, Takao Y, Maekawa N, Shiga M, Obara H: ONO-5 046 , an elastase inhibitor,...

Ngày tải lên: 18/06/2014, 19:20

... phosphorylation and transloca tion of cytosolic gIVaPLA2 to the nucleus, change in cell shape, polymerization of F- actin, tyrosine phosphorylation as well as enzymatic activity of proline- rich tyrosine kinase ... Severity of Endotoxin -Induced Acute Lung Injury. J Immunol 2006, 176 :49 95-5005. 6. Nishina K, Mikawa K, Takao Y, Maekawa N, Shiga M, Obara H: ONO-5 046 , an elas...

Ngày tải lên: 20/06/2014, 03:20

... mild hyperplasia of the synovial lining, but without any evidence of inflammatory cells being observed (Fig. 5A,B). There were some inflammatory cells in the contralateral synovial lining, but ... AIA = antigen- induced arthritis; ELISA = enzyme-linked immunosorbent assay; GAG = glycosaminoglycan; H & E = hematoxylin and eosin; IL = interleukin; TGF = trans- forming growth fact...

Ngày tải lên: 09/08/2014, 01:21