Báo cáo y học: "Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells" pdf

... follows: the BMP inhibitor chordin is produced endogenously during the osteogenic differentiation of human mesenchymal stem cells (MSCs); and blockade of the activity of the BMP inhibitor increases the ... of chordin knockdown on the expression of markers of osteogenic differentiation in human MSCsEffect of chordin knockdown on the expression o...

Ngày tải lên: 09/08/2014, 10:23

... polyamines by downregulating the activity of the biosynthetic e nzymes and upregulating the activity of the catabolic enzyme spermidine/spermine N 1 -acetyltrans- ferase (SSAT) [8]. The effect of ... cellular pools of putres- cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu- lating the activity of the...

Ngày tải lên: 17/03/2014, 23:20

... in the aggregated mixture of intact LA and that the intensity of the CD signal of the helical structure is much higher than that of other secondary structures, including b-sheet [50]. The key ... tumor cells of a partly folded variant of LA bound to oleic acid [35,36], the ability of the protein to bind histones [37,38] and the bactericidal activity of some of...

Ngày tải lên: 30/03/2014, 16:20

... biocontrol activity of C. laurentii by complementing it with LF23 extract. The role of LF23 extract consists of enhancing the antioxidant enzyme activity of the yeast colonising the apple wounds ... quantification of the P. expansum DNA present in the contaminated apples in the presence or in the absence of the different biocontro l agents. The quantity of DNA...

Ngày tải lên: 28/06/2014, 11:20

... does the eGFR II. The conversion of the S-Creatinine by any of the algorithms we tested does thus not contribute to a more effective understanding of the kidney function. The uncertainty of ... calculated from the year of birth to the year of sampling, irrespective of dates of birth or sampling. The population in neither of the catchment areas all...

Ngày tải lên: 08/08/2014, 16:23

... The severity of physical anhedonia was significantly related to the diagnostic sub- category of non-paranoid schizophrenia, to the positive symptoms score and to the negative symptoms score of the ... female (38%). Their mean age was 30.95 (± 8.91) years, (age range 17 to 50 years). They had a mean of 12.6 (± 2.7) years of education, a mean duration of illness of 6.9 (...

Ngày tải lên: 08/08/2014, 21:20

... Galle 1 and Werner Mayet 4 1 Department of Medicine, University of Mainz, Mainz, Germany 2 Institute of Pathology, University of Mainz, Mainz, Germany 3 Institute of Pathology, Professional Associations ... specimen. The upregulation of PR-3 in the lung of WG patients may therefore reflect the selected organ injury, whereas the histological hetero- geneity may represent...

Ngày tải lên: 09/08/2014, 03:24

... – the latter amount was calculated prior to the approval of biologicals for the treatment of ankylosing spondylitis [8]. The study from Sicras-Mainar and colleagues is the first calculation of ... sub- sample of 200 patients, self-perceived health and well-being were evaluated by applying the Fibromyalgia Impact Questionnaire, the Brief Pain Inventory, and the European...

Ngày tải lên: 09/08/2014, 14:21

... separated by the proximity of the cells to the joint space and the bone respectively, alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophic cells. ... and CS4, one of the monomers of the polysaccharide portion of proteoglycan, showed significantly enhanced production of these cartilage matrix proteins at day...

Ngày tải lên: 09/08/2014, 14:22

... pathogenesis of RA by antigen presentation, autoantibody production, and/or inflammatory cytokine production. Chemokines could enhance the accumulation of B cells in the synovium. The aims of this study ... CCR7, CXCR3, CXCR4 or CXCR5, and the expression of the various markers was analyzed by flow cytometry. CD19 + B cells were gated, and the frequency of expression...

Ngày tải lên: 09/08/2014, 14:22