Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt

... swelling, 1 = slight edema and erythema limited to the foot or ankle, 2 = slight edema and erythema from the ankle to the tarsal bone, 3 = moderate edema and erythema from the ankle to the tarsal bone, ... booster injection. The mean arthritis index was significantly lower in the tolerance group than in the CIA group throughout the examination period. Values are pre...

Ngày tải lên: 09/08/2014, 10:22

... express WT1 and/or carcinoembryonic antigen (CEA) as potential targets for the induction of antitumor immunity. In this study, generation of cytotoxic T lymphocytes (CTL) and regulatory T cells (Treg) ... in the presence of the supernatants resulted in generation of Treg. The abnormal function of DCs and dif- ferentiation into Treg in the local tumor mi...

Ngày tải lên: 18/06/2014, 15:20

... h. The slides were incubated with the primary antibody for one h after which they were then rinsed. Staining was car- ried out using the streptavidin-biotin kit (Dakocytoma- tion); the primary antibodies ... BHC, CWL, and CPY participated in the design of the study and performed the analysis. JSJ conceived of the study, and participated in its design and coordination a...

Ngày tải lên: 10/08/2014, 05:21

... conclusion that the N-terminal loop preceding the a-helix in scorpion toxins is one of the determinative domains in the interaction of toxins with the target ion channel. Keywords: birtoxin; ikitoxin; ... mice. The C-termini of scorpion toxins are hypothesized to be responsible for a significant portion of their toxicity. Gurevitz et al. [16] stated that the C-termi...

Ngày tải lên: 31/03/2014, 08:20

... patient’s myocardial ischemic burden at the time of the testing. Resting ECG analysis, including that of the 12-lead ECG, typically has significantly less sensitivity in detecting ischemia. Clinical ... diagnosis, the combination of these six transformations and the resulting 166 indexes does. To reach the final diagnosis, the index patterns of the individual s...

Ngày tải lên: 08/08/2014, 16:23

... lim itation of the present study was that the angiography results were not explicitly quantified using a scoring system [44]. Still, the assessment of coronary lesions in the study set forth ... have artificially reduced the calculated sensitivity and specificity of the 3DMP method. Another limitation of the study may have been patient recruitment. The patient...

Ngày tải lên: 08/08/2014, 17:20

... China) between 2008 and 2009. Informed consent was obtained from all patients, and the study was approved by the ethics committees of the participating institutions. Ten posi- tive samples with ... fraction and the remaining cell pellet as the insoluble fraction to de- termine whether native or denaturing conditions were necessary for protein purification. The superna- tant...

Ngày tải lên: 08/08/2014, 18:21

... set the stage for the human genome paper, which was soon to appear. Methods for identifying human genes To better understand the source of this continuing uncertainty about the gene count, ... sequence in another organism. Together with EST and cDNA alignments, gene finding by homology is the first step in all the major annotation pipelines. But even the most thorough...

Ngày tải lên: 09/08/2014, 20:21

... sequences are plotted. The bottom and top of boxes indicate the 25th and 75th percentiles, respectively, and bands in the boxes indicate medians. Whiskers indicate the lowest or the highest data points ... nuclear diameter from the periphery. This suggests that loci spa- tially close but not directly attached to the nuclear membrane are more transcriptionally competent t...

Ngày tải lên: 09/08/2014, 22:23

... future investi- gation. Particular attention should be paid to the fact that these fungi are characterized by intense pigmenta- tion, a phenotype that may be related to their patho- genicity. ... can be aligned to each other, indi- cating that the vast majority of genes lie in collinear regions and are shared between the two organisms. The aver age identity of the alignabl...

Ngày tải lên: 09/08/2014, 22:23