Báo cáo y học: "Cross-sectional analysis of adverse outcomes in 1,029 pregnancies of Afro-Caribbean women in Trinidad with and without systemic lupus erythematosus" ppsx

... pregnancy outcomes in women with systemic lupus erythematosus (SLE) and population controls in Trinidad. We performed a cross-sectional analysis of adverse outcomes in pregnancies of Afro-Caribbean women ... history, and the anticardiolipin antibody (ACL) status was established for women with SLE. A total of 1,029 pregnancies were reported (356 b...

Ngày tải lên: 09/08/2014, 10:22

... identify key molecules in the course of hy- poxia-induced apoptotic pathways. Such analysis of trophoblastic cells will, in the near future, yield in- sights into the mechanisms of preeclampsia and ... expression of many proteins involved in apoptosis, including the expression profiles of proteins involved in the mito- chondrial (bcl-2, bax, and bcl-x, etc.) and...

Ngày tải lên: 31/10/2012, 15:12

... Biochemistry of the Charité, Berlin, Germany using the ABI PRISM Big Dye Terminator system (Applied Biosystems, Germany). Sequences were analyzed using the Chromas software (Technely- sium Pty Ltd, ... frequency of 20% in samples of patients with AML and 13,7% in healthy individuals. After its confirmation by re-sequencing and digestion of selected samples with misma...

Ngày tải lên: 31/10/2012, 16:49

... maturation. With this in mind, we examined the mRNA expression levels of BAFF and APRIL within the thymocytes. These two genes are expressed by cells of lymphoid lineage, and are linked to increased ... 3. Protein levels of immunoglobulin increase within the thymocytes with age. Western blot analysis of IgM heavy chain protein levels with successive age. This image is...

Ngày tải lên: 03/11/2012, 11:35

... residues phenylalanine and tyrosine typical of the Ig-fold are bold in each domain. Fig. 5. Inhibition of in vivo myotoxicity of myotoxins I or II by DM64. Groups of four mice were injected intramuscularly ... first three domains and are present in the inhibitory receptors of Fig. 6. Inhibition of in vitro cytotoxicity of myotoxins I or II by DM64. Cytotoxicity was an...

Ngày tải lên: 21/02/2014, 01:21

... vitro [66], and disassembly of active units from an oligomeric (storage) state of a-crystallin was proposed, upon structural analysis of aA-crystallin by site- directed spin labelling, as a model ... (1992) Expression and aggre- gation of recombinant aA-crystallin and its two domains. Bi ochim. Biophys. Acta 1130, 267–276. 8. Augusteyn, R.C. (1998) a-Crystallin polymers and...

Ngày tải lên: 22/02/2014, 04:20

... a family of seven isoforms of enzymes involved in protein cross-linking, including prostatic TGase and factor XIII. tTG is a Ca 2+ -dependent ubiquitous intracellular enzyme that catalyzes the ... gluten and similar proteins in rye, barley and possibly oats [1], with gliadins, specific antigenic determinants found in glutens [2], playing a prominent role. The disease is chara...

Ngày tải lên: 08/03/2014, 09:20

... had unsubstituted hydroxyl group at C-1, and was mostly present in an a-pyranose form. Acyl 1 ,acyl 2 and acyl 3 residues had hydroxy or acyloxy groups at C-3 ( 13 C signals of C-3 at 69.0–72.4 ... 2-N-(3-O- acyl 4 -acyl 2 )-b-GlcN-(1–6)-2-N-acyl 1 )3-O-acyl 3 -GlcN where acyl 1 ,acyl 2 and acyl 3 are 3-hydroxyhexadecanoic or 3-hy- droxyoctadecanoic acids, acyl 4 is tetradecanoic or...

Ngày tải lên: 08/03/2014, 09:20

... spectroscopy the Bruker standard pulse programs INV 4 PRST (HMQC), INV 4 NDTP (HMQC without decoupling during acquisition), INV 4 MLPRTP (HMQC-TOCSY), INDECOBIMLTPPR (DEPT- HMQC-TOCSY), and INV 4 LRNDPR (HMBC) ... recorded with 4096 data points in F2 and 512 experiments in F1 over spectral widths of 10 and 120 p.p.m, respectively. Zero-filling was applied to 1024 data points i...

Ngày tải lên: 08/03/2014, 09:20

... substrate-accessing channel, and their guanidinium and hydroxyl groups, respectively, play crucial roles in the binding of the substrate by interacting with the carboxyl group of the substrate fatty acids ... activity of rP450foxy as observed with the native enzyme [28]. Dodec- anoic acid hydroxylase and NADPH-cytochrome c reduc- tase were assayed for rP450foxy and compare...

Ngày tải lên: 08/03/2014, 22:20