Báo cáo y học: "A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects" ppsx

... the chondrocyte suspension may Commentary A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects Rocky S Tuan Cartilage Biology and ... implantation of the gel-polymer based chondrocyte graft BioSeed-C. The engineered graft showed mostly hyaline cartilage with some fibrocartilage, and pre...

Ngày tải lên: 09/08/2014, 10:21

... Glu23 charge preceding the a-helix modifies the activity of this toxin in a unique way to result in reduced potency in mice. The C-termini of scorpion toxins are hypothesized to be responsible for ... known to bind to neurotoxin receptor site 4 of the voltage-gated Na + channel [5]. Recently their mechan- ism of action at the molecular level has become more apparent....

Ngày tải lên: 31/03/2014, 08:20

... laboratory of Dr Yaspo; the plasmid containing the cDNA of Runx1 was obtained from the laboratory of Dr Groner; the plasmid containing the cDNA of Sim2 was obtained from the lab- oratory of Dr ... Since the majority of the genes analyzed showed the highest level of induction after 24 hours of Tc deprivation, we decided to test the inducibility of the...

Ngày tải lên: 09/08/2014, 20:22

... industry deals with larger quantity of materials, these factors are particularly very important therein. Over the years, many reagents and catalysts have been developed for the synthe sis of oximes. ... Mizuno M, Miyake K, Minami N (1996) Synthesis of (2R)-1-(4-Chloro-2-pyridyl)-2-(2-pyridyl)ethylamine: a selective oxime reduction and crystallization-induced asymmetric transformatio...

Ngày tải lên: 20/06/2014, 22:20

... conversion of citral into methylheptenone and acetaldehyde is the addition of water to the a,b-double bond resulting in 3-hydroxyci- tronellal followed by rearrangement of the hydroxyl group leading to ... [31], respectively. Citral lyase is a monomeric enzyme of 30 kDa, which is approximately the monomeric size of these hydratase/aldolase enzymes. All of these enzymes...

Ngày tải lên: 21/02/2014, 01:21

... binds to the phosphotyrosine motifs pY343, pY401 and pY429pY431 of the EPO-receptor We and others have recently shown that SOCS-3 exerts its inhibitory activity on IL-6 signaling by binding to phos- photyrosine ... binds with higher affinity to pY429 pY431 than to pY401 As SOCS-3 was recruited by both pY401 and pY429pY431 we determined the affinities of the binding of SOCS...

Ngày tải lên: 24/03/2014, 00:21

... activity in chondrocytes is essential to induction of cell death by the CD95 pathway. This finding is Figure 3 Chondrocyte death consists of apoptosis and necrosisChondrocyte death consists of apoptosis ... activities. The phenotype of chondrocytes, however, was not affected by the activation of the CD95 pathway or inhibition of p38 MAPK, because they were positive for...

Ngày tải lên: 09/08/2014, 07:20

... locomotor activity of representative mice of the B6 and AhR strainsFigure 1 Raster actograms of locomotor activity of represent- ative mice of the B6 and AhR strains. Locomotor activ- ity was monitored ... by infrared motion detectors. Each line of recorded activity is 48 hr. Each pair of days is plotted beneath the previous pair of days. Activity is indicated by the...

Ngày tải lên: 10/08/2014, 09:20

... identify the type of cancer as a function of genes closely related to each distinct phenotype. With advance of microarray technologies, it is possible to conduct high throughput determination of the ... In the context of lung can- cer, microarray technology can be used to identify genes whose expression profile in a type of cancer differs from normal tissues or from ot...

Ngày tải lên: 10/08/2014, 09:22

... the site of involvement, the size of the cyst, and the pressure caused b y the enlarged cyst [1]. Usually, it presents as an inert, painless, non-inflammatory mass without any deterioration of the ... from the cyst wall are all specific to hydatid cysts [1-4]. Enhance- ment of the peri-cystic soft tissues can be considered an MRI feature suggestive of soft- tissu...

Ngày tải lên: 10/08/2014, 23:21