Báo cáo khoa học: " The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro" pdf

... surprising that TH8 is in the core because it is buried in the structure. Within the whole toxin, TH5 is partly covered by the C-terminal part of the receptor (R) domain [2,3]. Within the isolated T domain, ... to the functional state, which initi- ates the translocation of the catalytic domain. Here, the data allowed identification of the core of the...

Ngày tải lên: 16/02/2014, 09:20

... TZDs in 3T3-L1 adipocyte FEBS Journal 277 (2010) 687696 ê 2009 The Authors Journal compilation ª 2009 FEBS 689 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated ... adipocytes to resist apoptosis, adipocyte apoptosis is much less studied and is poorly understood. Recently, evidence from several in vivo and in vi...

Ngày tải lên: 16/02/2014, 09:20

... receptor coincides with queen flying age, and receptor silencing by RNAi disrupts egg formation in fire ant virgin queens Hsiao-Ling Lu, S. B. Vinson and Patricia V. Pietrantonio Department of Entomology, ... queen mating readiness. Silencing of the receptor in virgin queens through RNA interference abolished egg formation, dem- ons...

Ngày tải lên: 18/02/2014, 08:20

... 6A,B). The protein content in the 8K-BLP-treated disks increased significantly, and was A E B C D Fig. 3. Determination of the structure of 8K-BLP. (A) MALDI-TOF MS analysis of the purified peptide. ... Members of the insulin-like peptide (ILP) family are present in a wide variety of metazoans. In vertebrates, insulin and insulin-like growth factors (IGFs) regulate...

Ngày tải lên: 18/02/2014, 13:20

... ABC multidrug efflux pumps is assumed to correspond to the outward-facing confor- mation. The energy produced by the hydrolysis of ATP is harnessed for the resetting of the transporter to the ... Is ATP binding responsible for initiating drug translocation by the multidrug transporter ABCG2? Christopher A. McDevitt 1 , Emily Crowley 1 , Gemma...

Ngày tải lên: 18/02/2014, 18:20

... integral membrane proteins from the mitochondrial outer membrane, and of the 11 most abundant integral proteins, 10 had a-helical transmem- brane segments. Of these 10 proteins, most had a single ... trans- membrane segments that are assembled into the mito- chondrial outer membrane. Results and Discussion Integral membrane proteins in the mitochondri...

Ngày tải lên: 19/02/2014, 07:20

... Journal 273 (2006) 257270 ê 2005 FEBS 261 A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site Diana Herna ´ ndez-Romero 1 , ... repor- ted the existence and expression of a multipotent lac- case and a tyrosinase in Marinomonas mediterranea [11,13...

Ngày tải lên: 19/02/2014, 07:20

... reaction-centered graphs of the type o f Graph 1 (these paths may contain parallel and antiparallel arrows). The sign of that element therefore depends on the both the sign and the magnitudes of these influen ce paths ... the kinetic parameters t hat enable such oscillations. The main result of such an analysis is that oscillations arise if t he parameter k 3 is the l a...

Ngày tải lên: 19/02/2014, 16:20

... following results: a-1 antitrypsin, transthyretin and a-1- acid glycoprotein showed strong interactions with preprohepcidin. We further confirmed and examined the a-1 antitrypsin binding in vitro (glutathione S-transferase, ... MALDI-TOF) and in vivo (ELISA, cross-linking assay). Our results demonstrated that the serine protease inhibitor a-1 antitrypsin binds pre...

Ngày tải lên: 16/03/2014, 01:20

... cancer have poor survival in the first twenty months after operation and predictable survival in the medium and long-term: Analysis of survival and prognostic markers. World Journal of Surgical Oncology ... cancer, survive twenty months after operation, the prognosis improves and their survival becomes predictable. Introduction...

Ngày tải lên: 09/08/2014, 03:22

... applicable APC-derivatives ErPC and ErPC3 increase the radiation Increased cytotoxicity of ionizing radiation in combination with ErPC in U87MG cellsFigure 5 Increased cytotoxicity of ionizing radiation in combination ... membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of hu...

Ngày tải lên: 09/08/2014, 10:20

... Wilson et al.: Community capacity to acquire, assess, adapt, and apply research evidence: a survey of Ontario’s HIV/AIDS sector. Implementation Science 2011 6:54. Submit your next manuscript to BioMed ... ethno-racial communities, as well as people living with HIV/AIDS. Overall, we found organizational ca pacity to acquire, assess, adapt, and apply...

Ngày tải lên: 10/08/2014, 10:23

... REVIEW Open Access Recent advances in gastrointestinal oncology - updates and insights from the 2009 annual meeting of the American Society of Clinical Oncology Milind Javle 1 , Chung-Tsen Hsueh 2* Abstract We ... Clin Oncol (Meeting Abstracts) 2009, 27(18S):LBA4007. 56. Javle M, Hsueh CT: Updates in Gastrointestinal Oncology - insights from...

Ngày tải lên: 10/08/2014, 22:20

... species. Metabolic correlates of oxygen debt in determining the severity of shock and the effectiveness of resuscitation in humans Lactate The search for identifiable and easily measured metabolic correlates ... 1 Probability of death as a function of oxygen debt. (a) Regression-derived relation of Kaplan–Meier probability of death as a function o...

Ngày tải lên: 12/08/2014, 22:21