Báo cáo y học: "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis" docx
Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx
... providing an additional contact with the SH2 domain of SOCS-3 involving R94. A conforma-tional change induced by the phosphorylation of tyrosine Y4 31 may also contribute to the increase in binding affinity compared ... subtracted nonspecific binding. Determination of the dissociation constant wascarried out by Scatchard analysis [22].Peptide precipitation assay and immunoblot analysisApproximately 0.15 lmol of ... discuss the phosphorylation of tyrosine Y5 81 creating a more favourable conformation of the sequence surrounding the tyrosines Y5 79 and Y5 81, therebyincreasing binding affinity. Interestingly, the...
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Báo cáo Y học: A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus doc
... 2002 A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus A. Bora Inceoglu1,*, Yuki Hayashida2, Jozsef Lango3, Andrew ... Laboratory, University of California, Davis, CA, USAWe previously purified and characterized a peptide toxin, birtoxin, from the South African scorpion Parabuthus transvaalicus. Birtoxin is a 58 -residue, ... grant EY08120 (to ATI) and NEI CoreGrant P30 EY12576. A. B. Inceoglu is partially funded by AnkaraUniversity. Y. Hayashida and A. T. Ishida thank Dr B. Mulloney foruse of the voltage-clamp amplifier...
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Báo cáo y học: "Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis" pps
... coronary angiography in the study by Weiss et al. showed a higher sensitivity and specificity for the detection of coronary stenosis by 3DMP than by 12-lead ECG [18]. One limitation of the ... systems. In the case of the heart, analysis is performed on the signals emitted by the heart, such as the surface resting electrical signal recorded by an ECG. In systems analysis, the ECG ... about the potential superiority or inferiority of 3DMP to other ECG- based methods can only be drawn indirectly from other studies. In conclusion, the mathematical analysis of the ECG done by...
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Báo cáo y học: " Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis after coronary revascularization" doc
... nonobstructive coronary artery disease. Heart Dis. 2002; 4: 2-12. 22. Grube E, Bootsveld A, Yuecel S, et al. Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis. ... Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis after coronary revascularization Eberhard Grube1, Andreas Bootsveld2, Lutz Buellesfeld1, Seyrani ... coronary angiography in another study showed a higher sensitivity and specificity for 3DMP than for 12-lead ECG in the detection of coronary stenosis [21]. One limitation of the present study...
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Báo cáo y học: "Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia" ppt
... Monoclonal Antibodies against Nucleophosmin Mutants: Potentials for the Detection of Acute Myeloid Leukemia Shi Tan1, Ling Zhang1, Xiao-Ming Zhong1, Zai-Lin Yang2, Liu-Yang Zhao1, Yu-Jie ... value of their detection by immunocytochemistry. Blood. 2002; 99: 409-26. 17. Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. ... and antibody production were subjected to subcloning. Antibodies secreted by the 2G3 clones were found to be IgG iso-type. The specificity of the mAbs against NPM-mA was assessed by indirect...
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Báo cáo y học: "Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow" doc
... sIL-1R, increasing the binding affinity of IL-1α and IL-1β to type II sIL-1R byapproximately 100-fold, while leaving unaltered the lowbinding affinity of IL-1Ra to type II sIL-1R, thus enhancinginhibition ... arebroader and include activating or increasing the level of factors able to inhibit proinflammatory cytokines or othercatabolic factors.Interleukin-1βFor specific inhibition of the production/activity ... approaches to improving treatment of OA. The first section reviews the mostReviewMost recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrowJean-Pierre...
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Báo cáo y học: "Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis" docx
... responsible for most of the experiments, data analysis and drafting of the manuscript.HEH helped conceive of the study and shared responsibilityfor study design coordination and drafting of the manuscript.ES ... HMGB1 expression has been demonstrated in human and experimentalsynovitis. The aim of the present study was to elucidate the temporal and spatial expression of HMGB1 compared to that of the central ... and during the course of clinical arthritis. Local cytokine responses wereassessed by immunohistochemistry and by in situ hybridization.We demonstrate a distinct nuclear expression of HMGB1...
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Báo cáo y học: "Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis" pdf
... response.Identifying the signalling pathways that are involved in inducing the observed alterations in MMP expression maycontribute to our understanding of the initiation of kidneydamage in lupus nephritis. ... Candidatemediators of such changes include enzymes and signallingsubstances involved in maintaining the delicate balancebetween synthesis and breakdown of the proteins and proteoglycans that make up the ECM.Although ... understanding of MMP/tissue inhibitor of metalloproteinase function within the kidney, and discuss their possible involvement in the development and progression of lupus nephritis.IntroductionSystemic...
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Báo cáo y học: "between a chicken and a grape: estimating the number of human genes." pdf
... genes, and the total has steadily grown since then.Currently, the average number of genes listed in the human gene catalogs appears to be somewhere around 22,500, with an uncertainty of around ... uncertainty surrounding their numbers. In recent years, as a result of the dramatic breakthroughs in our understanding of RNA interference [7] and miRNAs [8], the number and variety of known ... number of orphans compared with the otherwise very small gene differences between humans and chimps, Clamp et al. rejected as implausible the alternative hypothesis that the orphans are human- specific...
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Báo cáo y học: "omparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi" pps
... dermatophyte genomes encode the basic meta-bolic machinery for glycolysis, tricarboxylic acid cycle,glyoxylate cycle, pentose phosphate shunt, and synthesis of all 20 standard a mino acids and the ... Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biology 2011 12:R7.Submit your next manuscript to BioMed Central and take full advantage of: ... dermatophytes and disclosed the peculiarities of the dermatophyte secondary metabolite gene sets. Secretion of proteases and other hydrolyticenzymes by A. benhamiae was proven experimentally by a...
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Báo cáo y học: "IV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics and sexually transmitted infections" pot
... problem among women of reproductive age. The behavior and other characteristics of the male partners in this study were important predictorsfor HIV in women. Therefore, involvement of men in HIVprevention ... regarding the male partner& apos;s behavior characteristics was reported by the women. The accuracy may be low due to lack of opennessregarding sexual matters between the partners, and prob-ably ... CentralPage 1 of 10(page number not for citation purposes)AIDS Research and TherapyOpen AccessResearchHIV among pregnant women in Moshi Tanzania: the role of sexual behavior, male partner characteristics...
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Báo cáo y học: " Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" doc
... cellsSince induction of cytolytic effector cells is pivotal in ensuring the success of tumor vaccines, we investigatedrelative efficacy of phytols and known adjuvants in theirability to augment ... formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responsesSo-Yon Lim1,2, Matt Meyer1,3, Richard A Kjonaas4 and Swapan K Ghosh*2,3Address: ... CentralPage 1 of 11(page number not for citation purposes)Journal of Immune Based Therapies and VaccinesOpen AccessOriginal research Phytol-based novel adjuvants in vaccine formulation: 1. assessment...
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Báo cáo y học: "Low-concentration, continuous brachial plexus block in the management of Purple Glove Syndrome: a case report" pps
... helped in physiotherapy and functional recovery of the hand in a month.Conclusion: A continuous blockade of the brachial plexus with a low concentration of bupivacaine and fentanyl helps to alleviate ... Glove Syndrome after intravenous administration of phenytoin. She was managed conservatively by limb elevation, physiotherapy and oral antibiotics. A 20G intravenous cannula was inserted into the ... erythema warrants immediate discon-tinuation of the infusion and removal of the intravenouscatheter [1]. The diagnosis of PGS is based on the characteristicclinical findings and a high index...
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Báo cáo y học: " Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study" docx
... Montero-Marín et al.: Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross-sectional University of Zaragoza study. BMCPsychiatry 2011 11:49.Submit ... 5.50). Burnout type, sociodemographic and occupational risk factors Table 3 shows the raw and adjusted ORs for the “fre-netic” burnout type. Only the number of hours workedper week and the type of ... characteristics.Methods: A cross-sectional study was carried out on a multi -occupational sample of randomly selected university employees (n = 409). The presence of burnout types was assessed by means of the “Burnout...
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Báo cáo y học: "Spinal manipulative therapy versus Graston Technique in the treatment of non-specific thoracic spine pain: Design of a randomised controlled trial" potx
... will be at least 18 years old with a primarycomplaint of thoracic pain (Figure 1: Mannequin defining the area of thoracic pain) and with no contraindicationsto manual therapy or Graston Technique. Upon ... trial performed assessing the effectiveness of spinal manipulative therapy on thoracic spinal pain [1].Spinal manipulative therapy (SMT) was compared to a placebo group receiving non functional ... assessing the efficacy of spinal manipulative therapy (SMT) for thoracic spine pain. In addition no high quality trials have been performed to test the efficacy and effectiveness of Graston Technique đ...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀMQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ