Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... Carcinogenesis and T ranslational Research (Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China Full list of author information ... the V5-V60, in increments of 5 Gy, were all found to be significantly associated with the incidence of SARP (see Additional file 2). These findings are consistent with ma...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... purposes) Radiation Oncology Open Access Research Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer Erik P Sulman, Ritsuko Komaki, ... Can electivenodal irradiation be omittd in Stage III non-small cell lung cancer? An analysis of recur- rences in a phase II study of induction...
Ngày tải lên: 09/08/2014, 09:22
Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc
... domains involved in protein–protein interactions and sub-cellular targeting [3,4]. TIA-1- related (TIAR) protein belongs to the RNA recogni- tion motif (RRM) family of RNA-binding-proteins. It is ... the abundance of each ARE-BP [53]. Interestingly, the down-regulating effect of ASF ⁄ SF2 is preserved upon inactivation of its RNA-binding ability by point muta- tions in both RR...
Ngày tải lên: 16/02/2014, 15:20
Báo cáo khoa học: Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells docx
... that is, down-regulating vimentin in the absence and in the presence of MTX. Targeting of vimentin was carried out by lipofecting aODN-VIM into paren- tal HT29 cells causing a decrease of 60% in ... dihydrofolate (DHF) [23]. This is followed by a rapid decrease in THF- cofactors that, while often incomplete, is associated with the cessation of THF-cofactor-dependent r...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "Rib fracture after stereotactic radiotherapy on follow-up thin-section computed tomography in 177 primary lung cancer patients" potx
... abnormal findings of the chest wall in addition to routine radiological assessment. Rib fracture in this study was defined as a disruption of cortical continuity with malalignment. Thinning of cortex ... approved the final version of this paper. A.N is the first author of this paper involved in interpretation of CT, clinical data collection, statistical analysis and d...
Ngày tải lên: 09/08/2014, 09:21
Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
... caveolin, a 21–24 kDa integral membrane protein, plays a critical r ole in the regulation of cell proliferation, including SMC, by inhibiting signalling mol- ecules [ 45–47]. Caveolin-3 is the main ... main isoform in muscle cells, including SMC [30]. Caveolin-1 and caveolin-3 seem to act as scaffolding proteins that negatively regulate the activity or the release of many molecule...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Interaction of the small heat shock protein with molecular mass 25 kDa (hsp25) with actin doc
... polymerization of intact actin. (A) Effect of HSP25 and its 3D mutant on the kinetics of actin polymerization. Samples containing 1–4 l M of actin (10% of pyrene-labeled protein) were incubated for 5 min in ... electrophoresis. (B) Time course of the disappearance of the band of unhydrolyzed actin during limited trypsinolysis of intact actin (1) or actin preincubated at 60...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo khoa học: Interaction of the general transcription factor TnrA with the PII-like protein GlnK and glutamine synthetase in Bacillus subtilis potx
... sensor of nitrogen availability in B. subtilis [1,9]. The feedback-inhibited form of GS binds tightly to TnrA, preventing its binding to DNA, with the most effective feedback inhibitors of GS being glutamine ... degraded within 15 min by proteolysis. By contrast, no degradation of TnrA was observed during this kind of shift experiment in B. sub- tilis AmtB-deficient and GlnK-de...
Ngày tải lên: 06/03/2014, 00:21
Báo cáo khoa học: Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines docx
... detailed analysis of leptin signalling in pancreatic beta cells, LEPR point mutants with single or combined exchanges of the three intracellular tyrosines were expressed in HIT-T15 insulinoma cells. ... the effect of leptin on AMPK in the insulinoma cell lines. As shown in Fig. 1C, lep- tin treatment failed to alter the activating phosphoryla- tion of AMPK in HIT-T15 cel...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc
... altering the conformation of the loop. His-tags were employed in a topological study of the major light harvesting chlorophyll a ⁄ b binding apopro- tein, Lhcb1 [18]. Interestingly, fusion of a His-tag ... light harvesting com- plex (LHCI), consisting of four members (Lhca1–4) of the chlorophyll a ⁄ b binding protein family. LHCI is bound along one side of PSI only, in the v...
Ngày tải lên: 07/03/2014, 21:20