Báo cáo khoa học: " SCLC extensive disease – treatment guidance by extent or/and biology of response?" pptx

... the significance of potential confounders like treatment of asymptomatic brain metastasis by PCI, prognostic relevance of metastatic pattern within the het- erogeneous group of ED -SCLC and subsequent ... increasing role in ED -SCLC. After thoracic radiation treatment, in-field relapse occurred in 24% of the cases as the first site of relapse [4]. Without local treatment...

Ngày tải lên: 09/08/2014, 09:22

... treatment of SBMA by leupro- relin, underscore the importance of analysis of huntingtin toxicity in the full protein context and the importance of elucidating the normal biological func- tion of huntingtin. ... models, aspects of the disease phenotype seem more similar to the human disease, with the exception of specific stria- tal cell loss. These models caused a rethinki...

Ngày tải lên: 23/03/2014, 07:20

... are supported by Guo et al.[57]whodemonstrate the accumulation of amongst others, sLDL-R in the medium of TACE– /– DRM cells transfected with TACE. No sLDL-R is detected in the medium of the untransfected TACE– /– ... number of cell surface receptors was assessed by binding of an anti-LDL-R monoclonal Ig (IgG- C7)at4°C. A 1-h treatment of HepG2 cells with PMA resulted...

Ngày tải lên: 23/03/2014, 12:20

... distribution of superlatives across different text genres. 4 Elements of a Computational Treat- ment of Superlatives For an interpretation of comparisons, two things are generally of interest: ... while only 38% of S3 judgements are. number of instances % of “vital” judgements % of “okay” judgements S1 46 87% 13% S2 15 59% 40% S3 8 38% 60% Table 2. Ratings...

Ngày tải lên: 20/02/2014, 12:20

... to be induced by administration of toxins or by genetic manipulations. This review will focus on the comparison of three types of rodent animal models used to study different aspects of PD: (a) ... Parkinson’s disease FEBS Journal 275 (2008) 138 4–1 391 ª 2008 The Authors Journal compilation ª 2008 FEBS 1391 Table 1. Summary of advantages and disadvantages of selected rode...

Ngày tải lên: 07/03/2014, 05:20

... status quo of an ongoing research study of collocations – an essential linguistic phenomenon hav- ing a wide spectrum of applications in the field of natural language processing. The core of the work ... and some of them have not been used for this purpose yet. A brief overview of these methods is followed by their com- parative evaluation against manually annotated data b...

Ngày tải lên: 08/03/2014, 04:22

... the meaning of commencer is a com- plex structure, but the value of ARG2 is not itself complex, and the type of ARG1 subsumes the type of ARG2. This is necessary since the value of the function ... atomic types and E be the set of boolean or func- tional ( ~) combinations of elements of EAT; we use z T ~, where ~ E E to say that any value of z must be of typ...

Ngày tải lên: 18/03/2014, 02:20

... rapamycin, and the combined treatment facilitated greater clearance of mutant proteins than either of the treatments alone (Fig. 2). A further screen of structural analogs of these three SMERs identified ... numbers of expanded polyglu- tamine aggregates in a cell-based assay with the excep- tion of nicardipine. Some of these new targets may be beneficial for the treatment of...

Ngày tải lên: 23/03/2014, 07:20

... Facilitation of nuclear transport of AR by HIP-1 depends on its C-terminal nuclear localization signal for HIP-1. In addition to that of AR, mediation of transcriptional activity of genes by other ... promoter. Treatment with androgen increases the nuclear fraction of AR as well as that of HIP-1, indicating that forma- tion of the HIP-1–AR heterodimer is involved in tran...

Ngày tải lên: 23/03/2014, 07:20

... pathways. Discussion HD, one of the most extensively studied neurological disorders, is representative of a number of inherited diseases. The initiation of the disease process depends on the size of polyglutamine tails ... followed by an early death at 1 0–1 3 weeks. Pathological examination of the brain revealed inclusions in the nucleus of most brain neuro- nes as early...

Ngày tải lên: 23/03/2014, 10:20