Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc

... andlate toxicity. As in our study, the acute toxicity consisted of dose- limiting GI toxicity. Application of the linear quad-ratic model indicates that 42 Gy in 2.8 Gy-fractions is bio-logically ... considerations The study intent was to determinate the DLT of escalatingdoses of RT delivered concurrently with a fixed dose of gemcitabine (300 mg/m2) administered on a weekly basiswithin the ... than radiation field sizes used in our CRT regi-men, because the RT volume is the most critical variableinfluencing GI toxicity in gemcitabine- based CRT regi-Table 2: GI toxicity: The different...

Báo cáo khoa học: " A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients" pdf

... patients including phase II and IIItrials comparing different agents in the treatment of radi-ation dermatitis. In one Phase III trial, 194 female patients receiving breast or chest-wall irradiation ... Application of the cream was accomplished with the ventral surface of the fingers using a rotary motion of the fingers with light pressure to the skin. The cream wasmassaged into the skin until ... assessment of patients whoreceived a higher total dose of radiation may be informa-tive.Cytokine and cellular responses to radiation therapy in the skin have been investigated to identify targets to...

Báo cáo khoa học: "A phase II randomized trial comparing radiotherapy with concurrent weekly cisplatin or weekly paclitaxel in patients with advanced cervical cancer" potx

... beenobtained in phase I studies using cisplatin -combination CTRT with either topotecan o r tira pazamine [60-62].Several phase I/ II studies are currently investigating the combination cisplatin-topotecan ... trial 0219 istesting the added value of tirapazamine to cisplatin forCTRT in carcinoma of the cervix.Therateofgastrointestinal(GI)toxicityinourstudymanifesting as severe diarrhea,washighinbotharmsalthough ... atleast 3 of the phase I studies that included paclitaxel,severe diarrhea was the limiting toxicity which agrees with our findings [31,39,40]. It is of concern that thisdifference in toxicity between...

Báo cáo khoa hoc:"A higher resolution radiation hybrid map of bovine chromosome 13" docx

... It is likely that the typing information of additionalmarkers in this chromosomal region improves the ordering capabilities of agiven mapping panel, leading to the revision of previous ﬁndings. The ... markers within the linkage groups are indicated at the far right side. Markers that connect ordered linkagegroups protrude on the right side of the middle axis. Loci ordered within the linkagegroups ... SwitzerlandbDepartment of Genetics and Microbiology, University of Pavia,Via Ferrata 1, 271000 Pavia, ItalycDivision of Genomics and Bioinformatics, Roslin Institute (Edinburgh),Roslin,...

Tài liệu Báo cáo khoa học: "A Mobile Touchable Application for Online Topic Graph Extraction and Exploration of Web Content" ppt

... intuitive touchableuser interface in order to either learn moreabout the content of a topic or to interactivelyexpand a topic with newly computed relatedtopics. In the ﬁrst step, the topic graph is ... measure of associationstrength is based on the pointwise mutual in- formation between chunk pairs which explic-itly takes their distance into account. An ini-tial user evaluation shows that this ... currently it containstoo much and redundant information. For exam-ple, the Wikipedia infobox for Justin Bieber containseleven basic relations whereas DBpedia has ﬁfty re-lations containing lots of...

Báo cáo khoa học: "A Cascaded Linear Model for Joint Chinese Word Segmentation and Part-of-Speech Tagging" pdf

... perceptron.will describe it in detail in Section 4. In this ar-chitecture, knowledge sources that are intractable to incorporate into the perceptron, can be easily incor-porated into the outside linear ... predicatingfails.3.2 Training AlgorithmWe adopt the perceptron training algorithm of Collins (2002) to learn a discriminative model map-ping from inputs x ∈ X to outputs y ∈ Y , where Xis the ... (3)While the mission of the training procedure is to tune the weights wj(j = 1 n) to guarantee that the candidate r with the highest score happens to be the best result with a high probability.As...

Báo cáo khoa học: "A Tree Sequence Alignment-based Tree-to-Tree Translation Model" potx

... the initial rules (i. e. lexicalized rules), in which the lexicalized TSRs model all non-syntactic phrase pairs with rich syntactic information. In addition, we find that the number of initial ... defines a kind of auxiliary rules to integrate forest- to- string rules into tree -to- string models. One prob-lem of this method is that the auxiliary rules are not described by probabilities since ... Extracting initial rules first. 2) Extracting abstract rules from extracted ini-tial rules with the help of sub initial rules. It is straightforward to extract initial rules. We first generate...

Báo cáo khoa học: "A Seed-driven Bottom-up Machine Learning Framework for Extracting Relations of Various Complexity" pdf

... properties of a pattern into account: • domain relevance: its distribution in the rele-vant documents and irrelevant documents (documents in other domains); • trustworthiness of its origin: the ... assigned the argument role infor-mation and a unique id. Step2: For i= 2 to n: (depicted in Figure 3) 1. find the set of the lowest nodes N1 in t that dominate in addition to other children ... <object:organisation> In (2), there is no further specification of whether the person entity in the subject position is Per-son _In or Person_Out. The ambitious goal of our approach is to provide...

Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identiﬁed substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf

... homodi-merization of CARP [49]. We therefore propose that the loss of CARP dimerization promotes the binding to titin by improving the accessibility of the titin-bindingdomain. Interestingly, the importance ... stimulation activates the interaction of a protein complex with the kinasedomain of titin, reducing the nuclear translocation of the transcription factor SRF and impeding gene tran-scription [16]. ... transcription regulator, cardiacankyrin repeat protein (CARP), and the calpain 3 protease was identiﬁed in the N2A elastic region of the giant sarcomeric protein titin. The present study aimed to investigate...

Báo cáo khoa học: "A Mention-Synchronous Coreference Resolution Algorithm Based on the Bell Tree" potx

... set of indices of the partially-established entities to the left of (note that ), and the set of the partially-established entities. The linkmodel is then(1) the probability linking the active ... mentionis linked with an in- focus partial entity while dashedarrows indicate starting of a new entity.added in the next step by either linking to the exist-ing entity, or starting a new entity. A second ... probability, aconstant is introduced to balance the linking proba-bility and starting probability and the starting probabil-ity becomes:(6)If , it penalizes creating new entities; Therefore,is...

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