Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc

... and late toxicity. As in our study, the acute toxicity consisted of dose- limiting GI toxicity. Application of the linear quad- ratic model indicates that 42 Gy in 2.8 Gy-fractions is bio- logically ... considerations The study intent was to determinate the DLT of escalating doses of RT delivered concurrently with a fixed dose of gemcitabine (300 mg/m 2 ) adm...

Ngày tải lên: 09/08/2014, 09:22

... patients including phase II and III trials comparing different agents in the treatment of radi- ation dermatitis. In one Phase III trial, 194 female patients receiving breast or chest-wall irradiation ... Application of the cream was accomplished with the ventral surface of the fingers using a rotary motion of the fingers with light pressure to the skin....

Ngày tải lên: 09/08/2014, 10:21

... been obtained in phase I studies using cisplatin -combination CTRT with either topotecan o r tira pazamine [60-62]. Several phase I/ II studies are currently investigating the combination cisplatin-topotecan ... trial 0219 is testing the added value of tirapazamine to cisplatin for CTRT in carcinoma of the cervix. Therateofgastrointestinal(GI)toxicityinourstudy man...

Ngày tải lên: 09/08/2014, 09:20

... It is likely that the typing information of additional markers in this chromosomal region improves the ordering capabilities of a given mapping panel, leading to the revision of previous findings. The ... markers within the linkage groups are indicated at the far right side. Markers that connect ordered linkage groups protrude on the right side of the middle axis. L...

Ngày tải lên: 09/08/2014, 18:21

... intuitive touchable user interface in order to either learn more about the content of a topic or to interactively expand a topic with newly computed related topics. In the first step, the topic graph is ... measure of association strength is based on the pointwise mutual in- formation between chunk pairs which explic- itly takes their distance into account. An ini- tial...

Ngày tải lên: 20/02/2014, 05:20

... perceptron. will describe it in detail in Section 4. In this ar- chitecture, knowledge sources that are intractable to incorporate into the perceptron, can be easily incor- porated into the outside linear ... predicating fails. 3.2 Training Algorithm We adopt the perceptron training algorithm of Collins (2002) to learn a discriminative model map- ping from inputs x ∈ X to...

Ngày tải lên: 08/03/2014, 01:20

... the initial rules (i. e. lexicalized rules), in which the lexicalized TSRs model all non-syntactic phrase pairs with rich syntactic information. In addition, we find that the number of initial ... defines a kind of auxiliary rules to integrate forest- to- string rules into tree -to- string models. One prob- lem of this method is that the auxiliary rules are not des...

Ngày tải lên: 17/03/2014, 02:20

... properties of a pattern into account: • domain relevance: its distribution in the rele- vant documents and irrelevant documents (documents in other domains); • trustworthiness of its origin: the ... assigned the argument role infor- mation and a unique id. Step2: For i= 2 to n: (depicted in Figure 3) 1. find the set of the lowest nodes N 1 in t that dominate...

Ngày tải lên: 23/03/2014, 18:20

... homodi- merization of CARP [49]. We therefore propose that the loss of CARP dimerization promotes the binding to titin by improving the accessibility of the titin-binding domain. Interestingly, the importance ... stimulation activates the interaction of a protein complex with the kinase domain of titin, reducing the nuclear translocation of the transcription...

Ngày tải lên: 29/03/2014, 21:20

... set of indices of the partially-established entities to the left of (note that ), and the set of the partially-established entities. The link model is then (1) the probability linking the active ... mention is linked with an in- focus partial entity while dashed arrows indicate starting of a new entity. added in the next step by either linking to the exist...

Ngày tải lên: 31/03/2014, 03:20