Báo cáo khoa học: "Reproducibility and geometric accuracy of the fixster system during hypofractionated stereotactic radiotherapy" pps
... The accuracy of the stereotactic treatment will among other factors depend on the reproducibility of the stereotactic frame and the positioning of the patient. It is necessary that the frame and the patient ... 0.7 mm for the GTC [12]. In the case of the Fixster system there is no study that has investigated the accuracy of the frame regardi...
Ngày tải lên: 09/08/2014, 09:22
... spectrophotometric methods. Because the enzymatic activity of PRTFDC1 towards hypoxanthine and guanine is only 0.26% and 0.09%, respectively, of the activity of HPRT, the role of the PRTFDC1 in purine metabolism ... II. The hood domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9...
Ngày tải lên: 15/02/2014, 01:20
... and ^ represent parallel and perpendicular polarized light, respectively. The bottom panel displays the result of deconvolution of the IR absorption spectrum of the peptide f or analysis of the ... IFP of ASLV-A and its membrane interactions to examine the difference in the biophysical property b etween the N-terminal and internal FPs, in the hope of impr...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Bioinformatic and enzymatic characterization of the MAPEG superfamily doc
... [57]. Isolation and cloning of the SynMGST and E.coliMGST The coding sequence for the SynMGST, corresponding to the complementary strand of the nucleotide sequence from 89 254 to 89 667 in the Synechocystis ... hydrophobic seg- ment. All of the remaining patterns are located at the end of first loop (Fig. 6). Both the first and third loop are located on the cyt...
Ngày tải lên: 19/02/2014, 17:20
Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... 257 rows 5 and 7 shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pK a of the latter by 0.8 pH units. The calculated effects of the D140N and D215N muta- tions ... for the position of residue 142 [34]. The pK a calculations indicate that the only candidate for a residue determining the basic arm of the pH-activity...
Ngày tải lên: 07/03/2014, 14:20
Báo cáo khoa học: Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p pptx
... parts of the N-terminal fragment and ⁄ or the second cassette; AB DC EF Fig. 5. Effects of point mutation of the WalkerA and B motifs of the AAA-cassettes of Pex6p on the morphological appearance of ... unknown. In this study we mapped the mutual binding sites and assayed the effects of deletion and point mutations in Pex1p and Pex6p for the interaction...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Spectroscopic and kinetic properties of the horseradish peroxidase mutant T171S Evidence for selective effects on the reduced state of the enzyme potx
... the ferrous state of the mutant may contribute to an increase in the disorder and hence entropy of the reduced state of the mutant compared to that of the wild-type protein. In contrast to the ... disposition of the proximal His and Asp residues, affecting the imidazo- late character of the His, but also by the formation of a LS species. The latter in...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Functional and genetic characterization of the promoter region of apolipoprotein H (b2-glycoprotein I) ppt
... activity restricted to the region 160 bp upstream of ATG codon, it does not eliminate the possibility of the functional roles of the )643T>C and )1219G>A SNPs as part of the extended APOH ... vector. The nucleotides are numbered from the translation start site (ATG). The effect of the wild-type and mutants was measured as the mean of the firefly luc...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus – the role of conserved residues in the active site pdf
... Stereo figures of the model of the bound substrate in the AD2 E526A mutant (A) and D524A mutant (B). The structures of bound sugars and the side-chains of three acidic residues in the conserved ... those of the substrates used in the kinetic experiments. The production of p-nitrophenol was linear with time for the incubation period, and < 5% of the...
Ngày tải lên: 15/03/2014, 11:20
Báo cáo khoa học: Conformational and functional analysis of the lipid binding protein Ag-NPA-1 from the parasitic nematode Ascaridia galli potx
... in quenching of protein Trp fluorescence and in an increase of the specific DAUDA emission after the noncovalent incorporation of the ligand. Binding of DAUDA to Ag-NPA-1 caused 20% quenching of the emission ... refractive index of the medium and K 2 the orientation factor, determined by the mutual spa- tial orientation of the transition dipole moments of...
Ngày tải lên: 16/03/2014, 18:20