Báo cáo khoa học: "Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?" ppt

... Access Research Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs? Carsten Nieder* 1 , Adam Pawinski 1 , Nicolaus ... from choosing 6 MeV. In 3 and 1 individuals, 12 MeV were necessary to cover the pre-pec- toral region adequately. In the prostate cancer patients, 9...

Ngày tải lên: 09/08/2014, 09:22

... differ- ences in cytokine levels in peritoneal fluid are different. It is very difficult for us to explain the findings and what that means for cancer disease. Previous studies were able to detect IL-1β in ... Surgical Oncology Open Access Research Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer: a mu...

Ngày tải lên: 09/08/2014, 04:21

... volumes receiving 100% and 150% of the prescribed dose; DHI = dose homogeneity index, (V 100 - V 150 )/V 100 . *Grade 1 to 2 toxicity. † Grade 1 to 2 toxicity. Five patients with asymptomatic ... local control, toxicity, and cosmesis comparable to those of conventional whole breast irradiation for select early-stage breast cancer. Patients with close resection ma...

Ngày tải lên: 09/08/2014, 09:20

... However, because of the increasing local experience in the admin- istration of BCT, increasing numbers of young patients in the population and increasing efforts to promote breast cancer awareness in recent ... conformal external beam radiotherapy to deliver accelerated partial breast irradiation in patients with early-stage breast cancer treated with breast-...

Ngày tải lên: 09/08/2014, 09:20

... DNA-binding domains involved in binding), or 1DR-short (as a dimer, but presumably with only one domain involved), or indeed when bound as a monomer to 1DR. This suggests that bind- ing to both inverted ... fit resulted in a binding stoichi- ometry of 2 : 1, i.e. dimer binding. The reactant con- centrations were too high to obtain relevant information on the binding affinity. For bi...

Ngày tải lên: 07/03/2014, 04:20

... subsequently interacts with dimer G al80p in the cytoplasm alone without translocating to the nucleus. The consequent nucleocytoplasmic shuttling of the Gal80p monomer from the nucleus to the cytoplasm relieves ... regulatory element of the GAL genes in the nucleus. The regulatory protein may bind to the upstream regulatory element constituting a protein– DNA interaction [4–6]. Th...

Ngày tải lên: 07/03/2014, 16:20

... acyl chains of PtdCho or sphingomyelin; however, neither the choline headgroups of PtdCho and sphingomyelin (except for a small peak in THP-1) nor the sphingosine chain of sphingomyelin were ... the top to the bottom of each gradient. Cholera toxin dot-blotting and SDS/PAGE immunoblotting Sucrose gradient fractions were examined for GM1 ganglio- side and protein content by cholera toxin ....

Ngày tải lên: 23/03/2014, 17:21

... analyzed in detail the interactions present in the designed complex, in which we introduced Hsp90- specific binding residues, mimicking the TPR2A binding interface. Consequently, we expected to find in the ... protein interactions comparable to those present in the naturally occurring Hsp90-binding TPR domains. A large energetic contribution to the binding of the peptide MEEVD...

Ngày tải lên: 29/03/2014, 08:20

... are involved in cell migration and attachment to the extracellular matrix proteins: vitro- nectin, fibronectin, fibrinogen, laminin, osteopontin, amongst others [38]. Vitronectin can bind to avb5 ... activation of integrins. Taken together, migration studies confirm the involve- ment of avb3 integrin in TPD52 mediated migration of LNCaP cells towards vitronectin. Similar to breast c...

Ngày tải lên: 30/03/2014, 02:20

... information content in the sum- maries that are generated automatically. Finally, recent research on analyzing online so- cial media shown a growing interest in mining news stories and headlines ... (Qazvinian and Radev, 2008), which employs document clustering. These papers try to increase diversity in summarizing documents, but do not explain the type of the diversity in their in...

Ngày tải lên: 30/03/2014, 21:20