Báo cáo khoa học: "Laparoscopic insertion of pelvic tissue expander to prevent radiation enteritis prior to radiotherapy for prostate cancer" pdf

... 6:47 http://www.ro-journal.com/content/6/1/47 Page 3 of 6 CASE REP O R T Open Access Laparoscopic insertion of pelvic tissue expander to prevent radiation enteritis prior to radiotherapy for prostate cancer Gary D McKay 1 , ... those with a low pelvic peritoneal reflection allowing loops of small bowel to enter the radiation field. Laparoscopic insertion...

Ngày tải lên: 09/08/2014, 09:20

... the negative findings of our study, further intensive studies are needed into strategies for inhibition of cytokine signaling as a way to ameliorat- ing lung toxicity from radiotherapy. Competing ... paradigm of IL-6: from basic science to medicine. Arthritis Res 2002, 4(Suppl 3):233-242. 9. Nishimoto N, Kishimoto T: Inhibition of IL-6 for the treatment of inflammatory d...

Ngày tải lên: 09/08/2014, 08:23

... planned total dose of radiotherapy. In this case radiochemotherapy was stopped after first cycle of chemotherapy at a dose of 43 Gy because of toxicity and old age of the patient. The intensity of ... 0.69). Colostomy free survival (CFS) 63 patients were colostomy free at the beginning of ther- apy. The actuarial colostomy free survival at 5 years was 84%. All colostomies were...

Ngày tải lên: 09/08/2014, 10:21

... converted into a PK-resistant isoform in the presence of NADPH. Aliquots of ScBH of SHa-263K were serially diluted into solutions of rSHaPrP or rHu- PrP, with final ScBH dilutions of 10 )3 ,10 )4 ,10 )5 and ... the influence of NADPH on the ability of PrP Sc to propagate in PMCA, a serial PMCA protocol con- sisting of seven rounds was conduced (Fig. 1A). Prior to mixing wi...

Ngày tải lên: 07/03/2014, 03:20

... the inhibitor of jB kinase, a regulatory role can be pre- sumed for USP7 phorsphorylation. The identification of K869 as the ubiquitination site of USP7 represents additional evidence for the interaction ... proteins. They are responsible for the disassembly of ubiquitin chains, and for the cleavage of mono- and oligomers of this mole- cule, either in precursor form or atta...

Ngày tải lên: 07/03/2014, 05:20

... viral promotor, about 40% of total rhodanese was found to be secreted into the culture medium [119]. Export was shown to occur in the absence of appreciable amounts of cell death and to depend ... activators of tumor-induced angiogenesis [45]. The majority of the members of the FGF family are exported by ER/Golgi- dependent secretory transport. However, FGF-1 and the 18 kDa...

Ngày tải lên: 17/03/2014, 03:20

... modi- fication of LDL is capable of eliciting cytotoxicity, differentiation, and inflammation in neuronal cells [10– 12,38]. Suppression of oxidative modification of LDL by antioxidants may be effective in preventing ... 1275 is cytotoxic to neurones and application of antioxi- dants may attenuate neurone death. Thus, inhibition of LDL peroxidation by antioxidants becomes an attrac...

Ngày tải lên: 23/03/2014, 10:21

... burst of NTP hydrolysis. We propose that the protonmotive force induces the conversion of IF1- inhibited F 0 F 1 -ATPase into a new form having a lower affinity for IF1. This form remains inactive for ... motor, with an asymmetrical rotor composed, in mitochondria, of c, d and e subunits, anchored to a membranous decameric ring of c subunits thought to compose a proton-driven tu...

Ngày tải lên: 23/03/2014, 12:20

... in A B Fig. 3. Iron storage and uptake activity of the 250 kDa protein. (A) Detection of iron in the 250 kDa protein: potassium ferrocyanide was added to a final concentration of 10 m M to all of the fractions ... degradation and the prevention of unwanted iron release into the cell. Unfortunately, the nature of this aggregation is unclear at present. It might be an intrinsic f...

Ngày tải lên: 23/03/2014, 13:20

... the C c -atom of H94 and the N 7-atom of CEOL: wild-type enzyme: 6.5 A ˚ ;W27Ymutant:6.1A ˚ ). The smallest distance between t he C c -atom of H94 and the inhibitor plane (N5-atom of riboflavin) ... the flavin c ofactor and appears to disfavour the formation of the electron rich hydrochinone form. Furthermore, p-stacking interactions play a role in protein binding of flavins. For...

Ngày tải lên: 30/03/2014, 15:20