Báo cáo khoa học: "The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis" pdf
Báo cáo khoa học: "The use of caspase inhibitors in pulsed-field gel electrophoresis may improve the estimation of radiation-induced DNA repair and apoptosis" pdf
... repair, and apoptosis itself.
Conclusions: The estimation of radiation-induced DNA repair by PFGE may be improved by the use of apoptosis
inhibitors. The ability to simultaneously determine DNA ... by the spontaneous DNA breakage in this medium. We investigated the mechanisms of this
fragmentation with the principal aim of eliminating it in order to...
Báo cáo khoa học: Combined use of selective inhibitors and fluorogenic substrates to study the specificity of somatic wild-type angiotensin-converting enzyme docx
... composition in the binding site of these
three ACE species were pinpointed. Together these data demonstrate that
the substrate selectivity of the N-domain and C-domain depends on the
ACE species. These ... mainly inhibit the activity
of one active site, allowing the determination of the kinetic
parameters of the other active site, free of inhibitor. For
each sp...
Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx
... altogether in the other constructs. (B) amino acid sequence of
the carboxyterminus of wildtype Bcl-2, Bcl-2 ActA, Bcl-2 cb5 and Bcl-2 ΔTM. The amino acids derived from ActA and cb5 are
shown in ... induction of both apop-
tosis [15] and ciPCD [2,12,13]. In fact, the ER may play a
key role in certain types of ciPCD, as intracellular calcium
influx caused by ER...
Tài liệu Báo cáo khoa học: "A Method for Correcting Errors in Speech Recognition Using the Statistical Features of Character Co-occurrence" pptx
... the counting of errors, and (2) the
effectiveness of the method in understanding the
recognized results.
655
string including errors, and the other is the corresponding
correct string (the ... 2: Take the string (Error-String) that comprises an
error-block and each M (5 in the experiment) character
before and after the error-block out of the input...
Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx
... which was indeed predicted. The other main
group, obtained 97% of the time in 20 740 explored
trees, contained the DIDO PHD sequences clustered
with the PHF and the CGBP proteins. As seen in the
tree, ... distribution (Fig. 1), in which the
SPP1 representatives are at the basal branch of CGBP
and DIO.
The GCBP proteins contain a PHD domain, fol-
lowed by a DNA...
Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf
... unfolding occurs. The detailed dissociation/unfold-
ing mechanism of the protein remains to be determined.
In this study, we examined the M
r
of the protein after
equilibration in various denaturing ... further increased. The unfolding curve
using the ANS fluorescence probe suggested a multistate
process, consistent with the results obtained by protein
intrinsic fluorescen...
Báo cáo khoa học: Cellular response to unfolded proteins in the endoplasmic reticulum of plants pptx
... chain is brefeldin A-insensitive and is
inhibited by the proteasome inhibitor clasto-lactacystin
b-lactone, resulting in the accumulation of ricin
A chains. These stabilized ricin A chains are partly
deglycosylated ... initial step
of the biosynthesis of dolichol-linked oligosaccharides
is blocked [46]. Treatment with tunicamycin results in
the inability of asparagine (N...
Báo cáo khoa học: A di-leucine sorting signal in ZIP1 (SLC39A1) mediates endocytosis of the protein doc
... membrane into the
cytoplasmic compartment by the di-leucine signal of
ZIP1 and substitutions of the di-alanine residues
for the di-leucine residues in the ZIP1 sorting signal
inhibited the internalization ... contrast, in the
presence of chloroquine, the total ZIP1-Myc accumula-
tion in the CHO cells expressing the wt ZIP1-Myc pro-
tein was increased to the...
Báo cáo khoa học: A novel retinol-binding protein in the retina of the swallowtail butterfly, Papilio xuthus docx
... staining of the gel indicates that
the fluorescing protein is one of the major components of
soluble proteins in the crude extract. The surface of the
fluorescing protein carries negative charge in ... cellular retinal-binding protein; CRBP,
cellular retinol-binding protein; IRBP, interphotoreceptor
retinoid-binding protein; RBP, retinol-binding protein.
Note: The nu...
Báo cáo khoa học: 2-Oxo acid dehydrogenase complexes in redox regulation Role of the lipoate residues and thioredoxin pot
... group and the residues modulating its
properties, (b) the interaction between the a3/3
10
and a1
helices and the length of the a1 helix and (c) the three
charged residues on the thioredoxin surface ... may regulate the activity of
the starting component E1 (a), produce output to surrounding medium
in the form of ROS (b) and reduce thioredoxin and disu...