Báo cáo khoa học: "A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer" doc

... 5:121 http://www.ro-journal.com/content/5/1/121 Page 9 of 10 RESEARC H Open Access A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer Robin J D Prestwich *† , Kiran Kancherla † , ... 2001, 127(2):135-9. doi:10.1186/1748-717X-5-121 Cite this article as: D Prestwich et al.: A single centre e...

Ngày tải lên: 09/08/2014, 09:20

... develop predicative tools for predicting the role of Ca 2+ and Ca 2+ -binding proteins in biological systems. Materials and methods Molecular cloning and modelling of engineered CD2.STIM1.EF The single EF-hand ... Ca 2+ -coordinating residues in positions 1 and 3 of the EF-hand motif significantly compromised the metal-binding capability of the engi- neered protein, indicating th...

Ngày tải lên: 07/03/2014, 00:20

... associated with luck in China and Denmark, but with bad luck in Nigeria and Ger- many and reflects ambition and desire in India. Some expressions involving colors share the same meaning across ... with red and brown, anticipation with green, fear with black, joy with pink, sadness with black, brown and gray, surprise with yel- low and orange, and finally, t...

Ngày tải lên: 22/02/2014, 02:20

... dis- tinct narrow time interval of transcription initiation [25], and regulate transactivation of several endoderm- and hepatocyte-specific factors, including transthyretin, albumin and tyrosine aminotransferase ... °C. Finally, the chip was rinsed in 0.05· SSC before drying by low-speed centrifugation. For staining, the chip was immersed in an NaCl ⁄ P i solution containing 10 lgÆmL...

Ngày tải lên: 30/03/2014, 04:20

... (CT) revealed thickening of the gastric wall and findings indicative of abdominal wall invasion. a b Figure 2 Macroscopic examination of the specimens.a.Upon macroscopic examination, the specimens ... immunohistochemically positive for CD68 and were non reactive with CAM5.2, AE1/3 and S-100 protein (Figure 3). The xanthogranuloma was located near to the gastric cancer, but w as not i...

Ngày tải lên: 09/08/2014, 02:20

... enzyme activities in vivo.We found that amphibian DNases I are characterized by a C- terminal end with a unique cysteine-rich stretch and by insertion of a Ser residue into the Ca 2+ -binding site, resulting ... deoxyribonuclease isolated from bovine, ovine, and porcine pancreas. Derivation of the amino acid sequence of ovine DNase and revision of the previously published amino acid...

Ngày tải lên: 20/02/2014, 23:20

... the squelching action of DNA following protein binding. However, interest- ingly, the protein regains a unique mode of aggrega- tion even when bound to DNA following an enhancement in the concentration ... presence of a single mismatch, thereby generating large protein ⁄ DNA complexes encompassing the mismatch. Results MutS interaction with MutL and stoichiometry analyses In this st...

Ngày tải lên: 07/03/2014, 12:20

... were present in all strains (Fig. 3), although their relative ratios were altered in strains mf1 and mf2, exhibiting an increase in band D and splitting of band C. All of these bands correspond ... of D2 and apoCP43 remained similar to those in the WT strain. We noted that labelling of D1 and apoCP47 were clearly detectable in 40 min pulses in mf1 and mf2 strains (Fig. 5...

Ngày tải lên: 07/03/2014, 15:20

... variants in the crystalline state were analyzed using the msd-pisa server [20] taking into account all the interactions of protein chains within the asymmetric unit as well as with symmetry equivalent ... enzymatic properties. Closer inspection, however, revealed that a glycine-rich loop in the vicinity of the isoalloxazine ring system with Gly106 directly interacting with C(2=O) of...

Ngày tải lên: 30/03/2014, 01:20

... co-ordina- tion with the subsequent loss in activity, without affecting substrate binding. Our band-shift experiments demonstrate that the RNA binding of the D209N mutant is not reduced and not in uenced ... metal binding inhibitor (10 mm EDTA). In some cases, these metal ligands can be sub- stituted with a water molecule or by another acidic residue in the vicinity, allowing the...

Ngày tải lên: 30/03/2014, 15:20