Báo cáo y học: "Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritis" pps

... examined the hypothesis that the Framingham score is increased and associated with coronary- artery atherosclerosis in patients with RA. The Framingham score and the 10-year cardiovascular risk ... in the Framingham risk score in patients and controls, and the majority of the SLE patients with coronary calcification had a low 10-year ri...

Ngày tải lên: 09/08/2014, 08:23

... cells. The second aim of the study was to determine whether downregulation of phagocyte activities are involved in the anti-inflammatory activity of anti-TNF-α therapy. The lack of activity on ... observed in patients during adalimu- mab therapy does not explain the decreased influx of neu- trophils into synovial joints previously observed in RA patients during...

Ngày tải lên: 09/08/2014, 06:22

... activity to study the validity of the Disease Activity Score and the DAS28. In a study performed in Italy in the late 1990s, it was found that the Disease Activity Score was the best measure to discriminate ... best the physician’s clinical judgement of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score...

Ngày tải lên: 09/08/2014, 07:20

... regardless of the etiology of such inadequacy. In contrast, vitamin B6 supplementation was ineffective in suppressing inflammatory cytokine production, or reducing ESR, plasma CRP or rheumatoid factor ... measured to examine the impact of pyridoxine treatment on vitamin B6 excretion in these patients. Pro-inflammatory cytokine (TNF-α and IL-6) production, C- reactive pro...

Ngày tải lên: 09/08/2014, 07:20

... pro-inflammatory responses to painful stimulation may play a deleterious role in shaping the long-term symptomatology of RA. Competing interests The authors declare that they have no competing interests. Authors' ... stressors on the physiology and symptomatology of patients with RA. Collectively, laboratory research has docu- mented a maladaptively pro-inflammatory res...

Ngày tải lên: 09/08/2014, 14:20

... incorporation of information from the clinical examination reduces the utility of routine CXRs, with only 3.4% leading to a change in management. The majority of the changes (78%) were related to repositioning ... radiography in a respiratory intensive care unit. Chest 1985, 88:691-696. 6. Silverstein DS, Livingston DH, Elcavage J, Kovar L, Kelly KM: The utility of...

Ngày tải lên: 25/10/2012, 10:45

... published by the University of Toronto Press. Prior, he was a student of psychology specialist at the University of Toronto, being awarded an academic scholarship from the University of Toronto. ... history can be obtained by asking the indi- vidual “how many times do you laugh during your regular day?” and have the individual rate their level on a scale of one to...

Ngày tải lên: 26/10/2012, 09:57

... alignments with bacterial cytochromes P450 has identified domains in the primary sequence of human CYP17 which are involved in the catalytic activity of the enzyme, i.e. substrate docking and binding, the ... conversion of PREG to DHEA, however, appears to differ with respect to the interaction of the enzyme with the 17-hydroxylated intermediate. Baboon CY...

Ngày tải lên: 08/03/2014, 09:20

... regulation of a range of components of the translational machinery, principally by changes in their phosphorylation, leading to modulation of their activities or their abilities to interact with one ... recycling of eIF2 to this form [29,30]. The activity of eIF2B can be modulated in a variety of ways [29,31] including by its own phosphoryla- tion, and through ph...

Ngày tải lên: 18/03/2014, 01:20

... only partially soluble in five of the constructs resulting in very poor yields. Intriguingly, in the sixth con- struct, the yield of soluble fusion protein with an extended carboxyl terminus of ... solubility of fusion proteins is not necessarily indicative of either proper folding or of increased solubility of the protein of interest. We propose that the succ...

Ngày tải lên: 23/03/2014, 21:20