Báo cáo y học: "Methotrexate enhances the anti-inflammatory

Báo cáo y học: "Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression" doc

... via A 2A and the A 3 adenosine receptors [8,9]. The highly selective A 3 adenosine receptor (A 3 AR) agonist IB- MECA (1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-9-yl]- N-methyl-β-D-ribofura-nuronamide) ... 6 Research article Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A 3 adenosine receptor expression Avivit Ocha...

Ngày tải lên : 09/08/2014, 08:23

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Báo cáo y học: "Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study" pptx

... significantly higher rates of the MetS [40]. This discrepancy may be a consequence of the ongoing inflammatory burden in the RA population, altering some of the components of the metabolic syndrome. The ... be the key to the underlying pathophysiology of the MetS, and can improve with folate replacement therapy [53]. Thus, suppres- sion of a potential precipitant...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: "Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat" ppsx

... neurons. We present the first in vivo report of the effects of neurturin upon the recovery of erectile function following bilateral cavernous nerve crush injury in the rat. Methods: In these experiments, ... oxide (NO) is synthesized, their loss after nerve injury is therefore chiefly responsible for the development of ED. Using this animal model of neurogenic ED, we have...

Ngày tải lên : 10/08/2014, 09:22

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Báo cáo y học: "Parvovirus B19 Genotype Specific Amino Acid Substitution in NS1 Reduces the Protein’s Cytotoxicity in Culture"

... 23). On the other hand, the non-structural protein of B19 (NS1) is a candidate mediator of direct cell injury. B19 virus targets erythroid cells via the major host cell receptor glycolipid ... To test the hypo- thesis that B19-associated liver pathology is related to the direct toxicity of persistent B19 NS1 in hepatocytes of previously infected individuals, we examin...

Ngày tải lên : 26/10/2012, 09:32

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Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"

... Frequency of the MTHFR genotypes and the result of the Chi square testing in the different studied groups. Showing the frequency and the results of the cross tabulation of the T allele and the different ... the thermolability of MTHFR. Actually, the frequency of the mutated allele was quite high, depending on the ethnic group analyzed [18-21]. Some au...

Ngày tải lên : 03/11/2012, 09:49

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Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt

... followed the kinetics of amylose synthesis over a 5-day period of nitrogen starvation and measured the amounts of starch, amylose, the k max of the starch fractions, the degree of crystallinity and the ... course of storage starch synthesis show that amylopectin and amylose synthesis are partly disconnected and that amylose synthesis persists when the rate of polys...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo Y học: Amino acids 3–13 and amino acids in and ﬂanking the 23FxxLF27 motif modulate the interaction between the N-terminal and ligand-binding domain of the androgen receptor pdf

... AR 3)13 deletion, whereas in the mammalian assay almost all reporter gene activity was lost. The most obvious difference between both assays is the coupling of AR.NTD to GalAD in the yeast assay, and the absence of a ... a-helix; FxxLF. The androgen receptor (AR) is a member of the steroid receptor subgroup of the nuclear receptor family of transcription factor...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

... content of 48.0% [43]. The GC content of the region essential for the biosynthesis of SPA in the other serotype strains (b–e) of A. actinomycetemcomitans is also lower than the average GC content of ... chromatograph spectra of the acetylated D -(+)-2- octyl glycosides obtained from the hydrolysate of the puriﬁed GDP-6- deoxytalose. (A) Glycosides of the puri...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: A new high afﬁnity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

... 0.12 pY429pY431 1.1 ± 0.03 F429pY431 4.6 ± 0.02 pY429F431 4.9 ± 0.02 Y4 2 9Y4 31 ND pY443 ND pY461pY464 ND Y4 61pY464 ND pY46 1Y4 64 ND pY479 ND Ó FEBS 2002 SOCS-3 binds to the pY429pY431 motif of Epo-R (Eur. J. ... phosphorylated peptide pY429pY431 (pYpY). In comparison, the mutation only marginally reduces the interaction with the single phosphorylated peptides pY429F431 (pYF)...

Ngày tải lên : 24/03/2014, 00:21

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Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx

... a heme covalently attached to the polypeptide chain via two thioether bonds, formed from the vinyl groups of the heme and the two cysteine residues in the consensus Cys-X-X- Cys-His motif [1–4]. ... T., Yamazaki, K., Kyogoku, Y. & Kobayashi, Y. (1998) Solution structure of thermostable cytochrome c-552 from Hydrogenobacter thermophilus determined by 1 H-NMR spectroscop...

Ngày tải lên : 24/03/2014, 03:21

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