Báo cáo khoa học: "The significance of the Van Nuys prognostic index in the management of ductal carcinoma in situ" pps
Báo cáo khoa hoc:" Adaptive significance of amylase polymorphism in Drosophila. Analysis of the association between tissue-specific expression and specific activity in Amy or Amy genotypes F S of Drosophila subobscura" ppt
... despite similarities in the protein structure, originate from changes in the polygenic complex of regulatory genes, examination of their variability is of importance. a-Amylase in Drosophila, ... of variance and correlation) were used for the analysis of the results. In this way, the variability in the number of active regions and...
Ngày tải lên: 09/08/2014, 18:21
Tài liệu Báo cáo khoa học: High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose pptx
... Seurin D, Segovia-Quinson B, Hardouin S & Binoux M (1986) Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding ... binding must only be a local effect because binding of PMP-BSA, which binds to other sites in the ectodomain of these heterodimers, resulted in the predicted amount of liga...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... folding of the mutant. The lower intensity may arise from partitioning of the protein into an aggregated state. The effect of copper binding on the secondary struc- ture was determined using CD in ... human cystatins. Further support for the premise that the C-terminus could be the copper binding domain comes from stud- ies of the P79S mutant, which differs from t...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identification of oscillophores ppt
... cycles in such a combination do not touch each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the magnitude of a Ôminus combined autoinfluence ... by the product of all the concentrations of its species. Therewith the c oefficient of o rder p of the characteristic equation equals the sum of al...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits ppt
... and 2 Department of Biological Regulation, The Weizmann Institute of Science, Rehovot, Israel A number of findings have suggested the involvement of protein phosphorylation in the regulation of the epithelial Na + channel ... expression of ENaC is determined by an interaction between the C tails of b and c and the ubiquitin ligase Nedd4. The WW domains of Nedd4...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... center of the enzyme. These modifications may be attributed to either the presence of the substrate and/or a product in the vicinity of the T2Cu active center rather than to disruption of this ... demonstrates that the whole process does not affect the integrity of the protein sample. The results of the titration are presented in Figs 5 and 6. As inferred i...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Saccharomyces cerevisiae Ybr004c and its human homologue are required for addition of the second mannose during glycosylphosphatidylinositol precursor assembly ppt
... we examined the ability of Ybr004cp-depleted cells to incor- porate [ 3 H]inositol into proteins. The ybr004cD-pGAL- YBR004c strain was grown and labeled with [ 3 H]inositol in medium containing ... prevented. These defects are a block in the incorporation of [ 3 H]inositol into protein, consistent with abolition of GPI anchoring, and the accumulation of a PI-PLC- resistan...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: 15-Deoxy D12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor c in human erythroleukemia cells ppt
... largely independent of 15d-PGJ 2 stimulation. Examination of PPARc ⁄ RXRa interactions within the PPRE To further investigate the identity and specificity of the DNA ⁄ protein interactions within the ... 6–8, respectively). The fidelity of PPARc:RXRa binding to the PPRE was further demonstrated by examining their binding to a c 32 P-labelled ds oligonucleotide spanning the...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: A (1fi3)-b-D-glucan recognition protein from the sponge Suberites domuncula Mediated activation of fibrinogen-like protein and epidermal growth factor gene expression pot
... curdlan or laminarin. After binding of the carbohydrate to the receptor, the expression of the gene coding for the binding protein increases. In turn, the potential scavenger molecule, a fibrinogen-related polypeptide, ... Expression of the (1fi3)-b- D -glucan-binding protein and the fibrinogen-like protein occurred in cells on the sponge surface, in the pin- acod...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: Cytosolic phospholipase A2-a and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus pdf
... the intensity of staining of the nuclear membrane in digito- nin-permeabilized cells was lower than that seen in Tri- ton X-100-permeabilized cells (Fig. 3B). Quantification of the intensity of ... blank. Relocation of cPLA 2 -a occurs to both the inner and the outer surfaces of the nuclear membrane In order to assess whether cPLA 2 -a was relocating to the inne...
Ngày tải lên: 16/03/2014, 18:20