Báo cáo khoa học: "Correction: Thyroid cancer causing obstruction of the great veins in the neck" pps
Ngày tải lên: 09/08/2014, 07:21
... invasive- ness in the development of prostate cancer. The antiproliferati ve effect of somatostatin may result from incr eased apoptosis. In breast cancer cells MCF-7, the cytotoxic effect of somatostatin ... features of prostate cancer progression from early stages to androgen independent stages, could mimic the development of prostate cancer clinically. Understa...
Ngày tải lên: 10/08/2014, 10:20
... the initial mixture. The fluorescence intensity was normalized by subtracting the contribution of the baseline slope using logarithmic fitting. The Tb 3+ -binding affinity of the protein was obtained ... demonstrate that the conformation of CD2 is unchanged. After the insertion of the helix–loop–helix EF-hand domain from STIM1, the helical content of the engineere...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus pdf
... that the C-terminal tail of the S cTXs are playing an important role in the biological activity of these toxins, and should constitute an important point of diversification of the interacting surfaces with ... for cysteine and X for any amino a cid), whereas the pair of cysteine residues of the b3 s trand is separated by only one amino acid residue (CXC), usually link...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: "A Chain-starting Classifier of Definite NPs in Spanish" docx
... follow the ACE terminology (NIST, 2003) but in- stead of talking of objects in the world we talk of objects in the discourse model: we use entity for an object or set of ob- jects in the discourse ... approach. In Proceedings of ACL 2003. 176-183. 53 pendent, the AnCora-Es corpus was mined to in- fer some linguistic hypotheses that could help in the automat...
Ngày tải lên: 08/03/2014, 21:20
Báo cáo khoa học: Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain pdf
... in the a,b active site. Taken together, the results of cleavage of compounds 3 and 5 show that the asymmetrically acting Ap 4 A hydro- lases can reach the scissile bond either by extending the ... cleavage of dinucleoside polyphosphate molecules modified in their ADP moieties. In addition, none of the oxymethylene analogs investigated inhibited the hydrolysis of A...
Ngày tải lên: 16/03/2014, 04:20
Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf
... modelling of PA enantioselectivity in the reverse reaction of amide bond synthesis also has pointed at the role of ArgB263 in this process [48]. The decomposition of interaction energies within the studied ... bonding network around ArgB263, the mentioned findings give another argument favouring the importance of ArgB263 in substrate binding to PA. The pronounced...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: "Speakers’ Intention Prediction Using Statistics of Multi-level Features in a Schedule Management Domain" ppt
... domain knowledge-level features). To evaluate the proposed model, we compare the accuracies of the proposed model with those of Reithinger’s model (Reithinger, 1995) by using the same training ... shown in Table 5, the proposed model outper- formed Reithinger’s model in all kinds of predic- tions. We think that the differences between accuracies were mainly caused by...
Ngày tải lên: 17/03/2014, 02:20
Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot
... complete loss of repression in M. maripaludis, whereas the muta- tion of the corresponding amino acid in the first NrpR domain (S168A) retained a normal regulation [22]. If the second NrpR domain of M. ... further verifying formation of a complex between NrpRI and NrpRII. The presence of 10 mm 2-oxoglutarate significantly decreased the binding of MBP–NrpRI to the o...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
... [5]. In the present minireview, the expression of relaxin-3 in the brain, and particularly its functions, including the stress response and food intake, are described. Expression of relaxin-3 in the ... consists of sig- nal peptides, and a B-chain, C-peptide and A-chain, and contains the RXXXRXXI motif in the B chain (B12–B19 in human) for binding to the relaxi...
Ngày tải lên: 29/03/2014, 21:20