Báo cáo khoa học: "Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia" docx

... Oncology Open Access Research Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia Hui Shien See 1 , ... characteristics and histological type with 30-bp deletion and XhoI-loss studiesin NPC tissue and plasma samples Number of 30-bp deletion i...

Ngày tải lên: 09/08/2014, 07:21

... determine the calcium-binding domain of the protein. (A) Schematic drawing of the recombinant proteins. Six GST-fused recombinant proteins containing the three distinctive domains of tandem repeat 1 ... recombinant proteins, rOMM-64-I, III, IV and V, which include the Glu-rich domain, were found to have calcium-binding activity. rOMM-64-II and -C and GST were stained red using ‘Stains-...

Ngày tải lên: 18/02/2014, 17:20

... binding of ACP to the docking site followed by a conformational change in ACP proposed to inject the acyl chain into the sub- strate-binding pocket [32]. If a similar mechanism is involved in ... wild -type, H298E and H298Q proteins in 30 min assays. The amount of labeled substrate present at the start of the reactions is shown in the first lane. C is a standard consisting of m...

Ngày tải lên: 19/02/2014, 08:20

... no significant protein–protein interaction between the two isoforms, which is in good agreement with the proposed independent ice-binding model of AFP [35,36]. Kristiansen and Zachariassen [4] ... preliminary X-ray structure of nfeAFP6 (data not shown) obtained was indistinguishable from that of ordinary type III AFP (i.e. HPLC12) [14,18]. There is a 41% sequence difference betwe...

Ngày tải lên: 16/03/2014, 04:20

... catabolism is mainly mediated by the effects of certain cytokines, such as tumor necrosis factor-a (TNF-a), interleukin-1β (IL-1β ), and interleukin-6 (IL-6) [4,8], the mechanisms associated with ... [23]. Ghrelin participates directly in hypothalamic regula- tion of nutrition, it causes weight gain by reducing food utilization, increasing food intake, and inhibiting leptin- induc...

Ngày tải lên: 09/08/2014, 03:22

... property correlated well with the infectivity of in uenza virus containing single amino-acid mutations in the fusion peptide segment of hemagglutinin [16]. Here we observed an inverse correlation ... & Nieva, J.L. (2000) Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: putative role during viral fu...

Ngày tải lên: 23/03/2014, 21:21

... anti-TB vaccine candidate. Rv2560 is a proline- and glycine-rich transmembrane protein, and may thus be classified as a simple sequence protein (SSP). This type of sequence is fre- quent in organisms having ... buffer for 15 min at 80 °C. After 1 h of blocking in Tris-buffered saline (NaCl ⁄ Tris) (0.05 m Tris in isotonic saline, pH 7.6) containing 0.05% BSA, the grids were inc...

Ngày tải lên: 18/02/2014, 16:20

... follows: aprotinin, leu- peptin, pepstatin A, AEBSF and proteinase inhibitor mixture that contains AEBSF, aprotinin, bestatin, E-64, leupeptin and pepstatin A from Wako Pure Chemical Industries (Osaka, ... of insulin-like growth factor binding protein-related protein-1 (IGFBP- rP1 ⁄ mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A asso...

Ngày tải lên: 19/02/2014, 07:20

... similarity with wmfvec. In In- degree, two senses are connected if their words are within a local window. We use the optimal window size of 6 tested in (Sinha and Mihalcea, 2007; Guo and Diab, ... the dominant topic based on the ob- served words in a definition (f inancial topic in bank#n#1 and stock#n#1) without further dis- cernibility. In this case, many senses will share...

Ngày tải lên: 19/02/2014, 19:20

... coarse-grained supervision is naturally abundant in the form of online review ratings. This coarse-grained supervision is, of course, less infor- mative compared to fine-grained supervision, how- ever, ... which is natu- rally abundant but less informative, with fine-grained supervision, which is scarce but more informative. To this end, we introduced two simple, yet effective, metho...

Ngày tải lên: 20/02/2014, 05:20