Báo cáo y học: "The in vivo expression of actin/salt-resista

Báo cáo y học: "Towards in vivo application of RNA interference – new toys, old problems" pdf

... for the analysis of gene function in many organisms in vitro and in vivo. In mammals, at present RNAi is mainly restricted to the analysis of easily transfectable cell lines in vitro, but here it ... knowledge of the mechanism of RNAi, the technical basis for its application to functional gene analysis in mammalian cells in vitro and in vivo, and potent...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt

... 2 Transient autoimmunity was induced in female C57BL/6 and actin-resistant, salt-resistant and hyperactive mutant of DNase I (ash .DNase I) mice by intraperitoneal injection with a single dose of ... and plasma in mice [17,18]. Impaired DNase I function has been implicated in the pathogenesis of SLE for many years since the initial observation that DNase...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis" ppt

... deviations. Data were analyzed by a nonparametric statistical analysis. An analysis resulting in value of P < 0.05 was considered statistically significant. Results HIF-1α mRNA expression in ... HIF-1α with the deviating from adaptation to hypoxia. We postulated that HIF- 1α is expressed in response to catabolic change in articular cartilage to maintain the cell viabili...

Ngày tải lên : 09/08/2014, 06:23

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Báo cáo y học: "Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles" ppt

... Metter A, Listing J, Sieper J, Braun J: Inflammatory back pain in ankylosing spondylitis: a reassessment of the clinical history for application as classification and diagnostic criteria. Arthritis ... 279:51897-51907. 27. Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T: PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regula- The following Additional files a...

Ngày tải lên : 09/08/2014, 14:22

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Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt

... Nanomedicine Research, National Health Research Institutes, Zhunan, Taiwan. 3 Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan. 4 Graduate Institute of Biomedicine and Biomedical Technology, ... proteomic profile and western blot analysis, the expression of LEG3 was exclusively increased in the injured spinal cord at day 14 post SCI, implying that active pha...

Ngày tải lên : 10/08/2014, 05:21

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Báo cáo y học: "Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis" ppsx

... characterization, and treatment of prostatitis, interstitial cystitis, and epididymitis in outpatient urological practice: the Canadian PIE Study. Urology 2005, 66:935-940. Journal of Inflammation ... inflammation and induction of healing and in the bladder. Our results therefore argue in favor of evaluating urinary TGF-β1 in IC patients in order to assess diseas...

Ngày tải lên : 11/08/2014, 08:22

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Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx

... of the native oxidase. In focussing on the main interaction domain on subunit II, we introduced additional mutations in exposed residues in the relevant area above the Cu A site (see Fig. 1 and Table ... functional binding site: Several attempts to eliminate a hypothetical second site have been made here for the bacterial enzyme by stripping subunits III and IV off...

Ngày tải lên : 22/02/2014, 07:20

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$Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot$

Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot

... This raises the possibility that any one or a combination of these properties may in uence the binding of apolipoproteins to lipoprotein particles. The capacity to fractionate lipid emulsions into ... lipid particles, are notably distinct in their maximum binding capacities (Table 2). In particular, the binding footprint for the apoE4 isoform, corresponding to 3.0 amino a...

Ngày tải lên : 08/03/2014, 09:20

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Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt

... cytosolic isoenzyme. In fact, under conditions where the cytosolic AAT was stable, there was a thermal instability of mitochondrial AAT at 70 °C [22]. The activity of mitochondrial AAT was taken ... inhibited by the addition to the mitochondrial suspension of CsA (Fig. 5A) , the speciﬁc inhibitor of the permeability transition pore of mitochondria [26]. This change...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo y học: Advances in the Surgical Management of Chronic Rhinosinusitis" pot

... mention the diagnostic methodology and a classification of CRS. CRS is primarily a clinical diagnosis based on history and physical examination. The physical examination of the sinusitis patient ... cell) Agger nasi air cell Advances in Surgical Management of Rhinosinusitis — Wright and Frenkiel 25 Perhaps the most significant and exciting innovation in the a...

Ngày tải lên : 08/08/2014, 20:23

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