Báo cáo y học: "Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technolog" ppt
Báo cáo y học: "Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technolog" ppt
... with rheumatoid arthritis. This was
done by applying microarray technology on multiple synovial
biopsies obtained from the same knee joints. In this way the
relative levels of intra-patient and inter-patient ... 2
Research article
Variability in synovial inflammation in rheumatoid arthritis
investigated by microarray technology
Johan Lindberg
1
, Erik af Klint
2
,...
Báo cáo y học: "A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity" doc
... studies investigating the potential role
played by reduced reactive oxygen species production in human
RA have yet been reported. In order to examine the role played
by the NOX complex in RA, we investigated ... using this stringent method.
The EIRA study included mainly individuals born in Sweden.
Taking those born outside Sweden into consideration also,
97% were of Caucasian o...
Báo cáo Y học: Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion pptx
... progress curve analysis of BTC hydrolysis
by recombinant wild-type human BuChE, by four selected
mutants (Y3 32A/D70G, Y3 32D/D7 0Y, W82A, A32 8Y)
and by commercial horse serum BuChE in the presence ... wild-type enzyme, in
the A32 8Y mutant and in the ÔcompensatoryÕ mutant
(Y3 32D/D7 0Y) . It can only be perceived in Y3 32A/D70G
mutant but is absent in the W82A and in...
Báo cáo Y học: Bass hepcidin is a novel antimicrobial peptide induced by bacterial challenge pptx
... regulated by
complex interactions of cytokines and protein kinases, and
mediates transcription of acute phase response genes by
binding to the interleukin (IL)-6-responsive element in the
promoters ... The
peptide may enter the hepatic vein or portal system directly,
or may be secreted into bile and enter the portal system by
re-absorption in the intestine. As bass hepcidin was foun...
Báo cáo y học: "Natural killer T cells and rheumatoid arthritis: friend or foe" ppt
... actively
contribute to synovial inflammation by residing in a niche
where they are usually absent. Hence, Vαi NKT cells were
reported to appear within the synovium of wild-type mice
as early as ... mice to healthy mice causes inflammatory
arthritis by deposition of autoantibody in joint spaces,
inducing an inflammatory cascade with activation of
complement and Fcγ receptor pathw...
Báo cáo y học: "dentification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model" doc
... online supplementary materials, and
their rat orthologs were obtained by querying NCBI Homolo-
Gene database [34]. The Gene Ontology (GO) analysis was
carried out by using GoMiner, developed by ... practically every tissue, they bear rich information regard-
ing inflammation and immune responses [23]. Thus, blood –
increasingly being recognized as a sentinel tissue – is uniquely
suite...
Báo cáo y học: "HLA-DRB1 genes and extraarticular rheumatoid arthritis" potx
... associated with Felty’s syndrome. When
considering the influence of DRB1 genotypes, the findings are
very similar. Genotypes containing two shared epitope
positive DRB1*04 alleles (in most cases, ... as DRB1*0401/DR7
carry more limited risks [3].
The Turesson study includes patients with extraarticular RA
defined by cutaneous vasculitis, neuropathy, Felty’s
syndrome, intersticial lung dise...
Báo cáo y học: " Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides" potx
... obese 10 years before interview was marginally
associated with increased RA risk. Furthermore, having a
physically demanding job 10 years before interview was asso-
ciated with significantly increased ... original categories enumerated by consecutive numbers starting with one.
g
Including only individuals who were employed.
h
Physician-verified diagnosis
before age 45 years. CI, confiden...
Báo cáo y học: "The relationship between cancer and rheumatoid arthritis: still a large research agenda" ppsx
... PTPN22,
STAT4). Finally, the clinical relevance of these data regarding
RA and malignancy is unclear. Should clinicians screen RA
patients differently than typical patients?
Competing interests
The ... between anti-cyclic citrullinated peptide antibody
status and malignancy. Is the risk of lymphoma primarily seen in
certain subgroups? This risk might be magnified by specific
genetic risk...
Báo cáo y học: "Global fitness profiling of fission yeast deletion strains by barcode sequencing" pptx
... isolated lysine aux-
otrophic mutants corresponding to seven genes, which
encode enzymes involved in lysine biosynthesis [25]. Five
of them, lys1, lys2, lys3, lys4, and lys7, have been cloned.
In addition, ... to
sequencing errors is unlikely to happen [22]. Using such
multiplex indexes, we routinely combined six-to-nine
samples in each sequencing lane. We sequenced the PCR
products for...
Từ khóa: