Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc

... implicates citrullinated α-enolase as a candidate autoantigen that could drive the chronic inflammatory response in RA. Introduction Rheumatoid arthritis (RA) is a common and disabling disease affecting ... Sugaya M, Hanagiri T, Yasumoto K: [Tumor marker in primary lung cancer]. J UOEH 2004, 26:473-479. 38. Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M, Naga...

Ngày tải lên: 09/08/2014, 07:20

... steadily increases, and today we can say that patients with chronic inflammatory diseases such as rheumatoid arthritis (RA) show abnormal stress responses leading to proinflammatory consequences. Stress can ... important and original aspect of the work of Edwards and colleagues is the fact that pain testing increased serum levels of TNF, which was not demonstrated in healthy contr...

Ngày tải lên: 09/08/2014, 14:21

... recombinant human insulin and human transferrin from Wako, Osaka, Japan; and nickel- nitrilotriacetic acid agarose from Qiagen Inc., Chatsworth, CA, USA. Recombinant human thioredoxin was kindly Correspondence ... 2002 Characterization of selenoprotein P as a selenium supply protein Yoshiro Saito* and Kazuhiko Takahashi Department of Hygienic Chemistry, Graduate School of Pharmaceut...

Ngày tải lên: 31/03/2014, 08:20

... (VEGF) and platelet-derived endothelial cell growth factor (PD-ECGF; also known as thymidine phos- phorylase) and, as a consequence, an increased APAAP = alkaline phosphatase/antialkaline phosphatase; ... 95:7987-7992. 23. Mazure NM, Chen EY, Laderoute KR, Giaccia AJ: Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signa...

Ngày tải lên: 09/08/2014, 01:21

... TNF and a related cytokine, lympho- toxin alfa (LTα), also play an important role in the develop- ment and homeostasis of secondary lymphoid organs [8]. Studies in mice suggest that TNF plays a ... unclear what effects anti-TNF treatment can have on B cells in RA and whether any effects influence the efficacy of these agents. In patients with RA, anti-TNF agents sometimes can...

Ngày tải lên: 09/08/2014, 14:22

... circulating adiponectin may be involved in cardiovascular disease in RA patients. Although this contradiction was partly explained by the induction of tol- erance to inflammatory stimuli by adiponectin ... Sata M, Arita Y, Nishida M, Maeda N, Kumada M, Okamoto Y, Nagaretani H, Nishizawa H, Kishida K, Komuro R, Ouchi N, Kihara S, Nagal R, Funahashi T, Matsuzawa Y: Role of adiponect...

Ngày tải lên: 09/08/2014, 14:22

... Sawada T, Suzuki M, Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono M, et al.: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid ... K, Ochiai A, Hirohata S, Shimizu M, Watanabe Y: High diagnostic value of anticalpastatin autoantibodies in rheumatoid arthritis detected by ELISA using human erythrocyte calpasta...

Ngày tải lên: 09/08/2014, 08:23

... identified 1 gastric and 1 colon cancer patient in our study. An early gastric cancer was di- agnosed on biopsy of a suspicious ulcerated area in a 45-year-old man patient. Partial gastrectomy was su ... ccessful and rema ins w el l. An 82 -year-old man was diagnosed adenocarcinoma by endoscopic biopsy. A right hemicolectomy was performed, and the patient had no any metastas...

Ngày tải lên: 25/10/2012, 11:18

... amplified by PCR using full length HBV DNA (adw2 serotype) as the template. The oligonucleotide primers were designed as follows: 5’-TTAGGCCTAAAAATGGAGAACATCACATCAGGA-3’ 5’-AAAACAGAGACCCATATGTAAATTGGTACCAATT-3’ ... Construction of cDNA Library in S. cerevisiae DSY-2 Strain The cDNA library was prepared by transforming the yeast S. cerevisiae DSY-2 strain, in which the cDNA mi...

Ngày tải lên: 02/11/2012, 11:08

... Köln, Germany) were used. The antibody directed against collagen type I was diluted 1:1000, the antibody against collagen type II was diluted 1:400, and the antibody against COMP was used at a 1:300 ... roles in joint physiology and disease, as well as in induction of regenerative processes within osteoarthritic joints. Methods Patient characteristics Human osteoarthritic cartilag...

Ngày tải lên: 09/08/2014, 01:23