Báo cáo y học: "Antibodies against the CB10 fragment of type

Báo cáo y học: "Antibodies against the CB10 fragment of type II collagen in rheumatoid arthritis" pdf

... increased the sen- sitivity of detection of antibodies in serum against NCII from Figure 2 Purification of CB peptides of type II collagen (CII)Purification of CB peptides of type II collagen (CII). ... CIICorrelation of antibodies against bovine type II collagen (CII) and human CII. Scatter plot of the levels of IgG antibodies against human C...

Ngày tải lên : 09/08/2014, 01:23

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Báo cáo y học: "Antibodies to mutated citrullinated vimentin and disease activity score in early arthritis: a cohort study" docx

... van der Linden S: Determination of the minimal clinically important difference in rheumatoid arthritis joint damage of the Sharp/van der Heijde and Larsen/Scott scoring methods by clinical experts ... the clinical diagnosis of rheumatoid arthritis (RA) in early arthritis, using cut off values recommended by the manufacturers of the tests. A total of 162 patient wi...

Ngày tải lên : 09/08/2014, 10:22

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Báo cáo y học: "Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients" doc

... underlying disease and furthermore on the clinical symptoms. Interestingly, the majority of patients showed reactivity to only one of the two major autoantigens. Only 37.1% of anti-PM/Scl-positive ... Vlachoyiannopoulos PG: European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. III. Assessment of the construct validity of the prelimina...

Ngày tải lên : 09/08/2014, 01:22

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Báo cáo y học: "Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases" pps

... declare that they have no competing interests. Authors' contributions YY carried out the immunoassays, participated in the data analysis and in the design of the study, and drafted the manu- script. ... and possibly secondary con- formational changes help the binding of anti-RPA antibodies in autoimmune sera. We examined whether the binding of DNA to RPA can int...

Ngày tải lên : 09/08/2014, 08:22

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Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"

... frequently terminated if the fetus is severely affected. Thus, the rate of defects is calculated for informative offspring including (i) live born infants, (ii) stillborn fetuses, and (iii) prenatal ... spectrum of congenital abnormalities evaluated, the period of study (only at birth or in early neonatal period or prenatal or the whole infant period are included), the...

Ngày tải lên : 02/11/2012, 11:12

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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

... germline gene therapy. 2. Criteria for Assessing Applicability to Human Germline Gene Therapy An ideal gene transfer system in the context of human germline gene therapy would have the following ... studies have indicated that exogenous DNA becomes concentrated within the posterior part of the nuclear area of the head, the inference being that binding of DNA by the...

Ngày tải lên : 03/11/2012, 10:01

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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt

... pasted into the structural alignment. The alignment was then corrected by hand. Since the sequences of the two arginases and agmatinase greately differ in the N terminal region, the agmatinase ... deletions in the agmatinase sequence were modelled using the DGLOOP set of options in WHATIF ; the whole loops and the two connecting amino acids at the beginning and...

Ngày tải lên : 21/02/2014, 01:21

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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx

... H A -hydrogen of IPP. In both cases, scrambling of the label takes place within the IPP pool and the error is then transcribed into the DMAPP pool by the normal action of the isomerase. The validity of the proposed ... Stereochemistry of the isoprenylation of tryptophan catalyzed by 4-(g,g-dimethylallyl) tryptophan synthase from Claviceps, the ﬁrst pathway-sp...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo Y học: Substrates modulate the rate-determining step for CO binding in cytochrome P450cam (CYP101) A high-pressure stopped-ﬂow study pdf

... for the polarity and therefore for the presence of water molecules in the heme environment of cytochrome P450cam. To get a further insight into the dynamics of the water exchange process in different ... 0.0113 a b is the isothermal compressibility determined from the following equation using the absolute value for the slope of the linear pressure- induced red-...

Ngày tải lên : 08/03/2014, 23:20

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Báo cáo khoa học: Intrabodies against the EVH1 domain of Wiskott–Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells potx

... intrabodies synthesized in the ER are released from the ER membrane into the cytosol by retro-translocation in lymphocytes including T cells [25]. In general, when proteins synthesized in the ... assessed their binding activity to the WASP-EVH1 domain in the scFv gene-transfected T cells. Finally, we succeeded in expressing the functional scFv intrabodies in t...

Ngày tải lên : 16/03/2014, 14:20

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