Báo cáo y học: "Susceptibility of rheumatoid arthritis synovial fibroblasts to FasLand TRAIL-induced apoptosis is cell cycle-dependent" ppsx

... proliferate. Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis Next, we analysed the cell cycle dependency of FasL- and TRAIL-induced programmed cell death of RASFs ... of tumour necrosis factor-related apoptosis- inducing ligand (TRAIL) receptors on rheumatoid arthritis synovial fibroblasts (RASFs)Surface exp...

Ngày tải lên: 09/08/2014, 01:22

... the perpetuation of disease. However, there is no guarantee that the mechanisms of late disease are identical to very early rheumatoid arthritis. Evaluation of the cytokine profile at the earliest ... lympho- cyte cytokine profile in chronic RA synovium and surface chemokine receptor display is most consistent with a T helper cell type 1 (Th1)-driven disease [5]. This cell...

Ngày tải lên: 09/08/2014, 06:23

... characteristics of patients with rheumatoid arthritis and control subjects. Characteristic Patients with early rheumatoid arthritis (n = 89) Patients with long-standing rheumatoid arthritis (n ... Avalos I, Stein CM: Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factors. Arthritis Rheum 2005, 52...

Ngày tải lên: 09/08/2014, 08:23

... follow-up of EBV-specific T -cell response is necessary and the role of non-EBV-related mechanisms of lymphomagenesis is not excluded. Introduction Rheumatoid arthritis (RA) is associated with a twofold increase ... mononuclear cell; PCR: polymerase chain reaction; RA: rheumatoid arthritis; SpA: spondy- larthropathy; SFC: spot-forming cell; TNF: tumor necrosis factor. A...

Ngày tải lên: 09/08/2014, 14:21

... Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF- alpha antibody with the interleukin 1 receptor antagonist. Eur Cytokine ... Role of cytokines in inflammatory synovitis. The coordinate regulation of intercellular adhesion molecule 1 and HLA class I and class II antigens in rheumatoid synovial fi...

Ngày tải lên: 09/08/2014, 01:21

... for rheumatoid arthritis. Keywords: hypoxia, oxidation, rheumatoid arthritis, synovitis 272 expression that was confined primarily to the lining cells of RA tissues with a particularly hyperplastic ... JR, Hwang BY, Lee HY, Song EK, Yoo WH: NF- κκ B-dependent lymphocyte hyperadhesiveness to synovial fibroblasts by hypoxia and reoxygenation: poten- tial role in rheumatoid a...

Ngày tải lên: 09/08/2014, 01:24

... programmed cell death (apoptosis) in the inflamma- tory synovium [5-7] might play a role similar to surgical synovectomy. Hyperplasia of the rheumatoid synovium may result from the imbalance between cell ... RA synoviocytes, may lead to inadequate apoptosis and tumor-like proliferation of rheu- matoid synoviocytes [8-11]. Thus, the induction of apoptosis by gene transfer...

Ngày tải lên: 09/08/2014, 07:20

... methotrexate dose of the original course was low. Introduction Rheumatoid arthritis (RA) is a chronic, autoimmune, inflamma- tory disorder of unknown aetiology that is characterized by symmetric synovitis and ... in rheumatoid arthritis: a long-term prospective study of 109 patients. Arthritis Rheum 1998, 41:1470-1480. 2. Eberhardt KB, Fex E: Functional impairment and disab...

Ngày tải lên: 09/08/2014, 07:20

... selected hydroxylated Editorial Androgens in rheumatoid arthritis: when are they effectors? Maurizio Cutolo Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal ... relationships Activation of the hypothalamus-pituitary-adrenal axis by pro- inflammatory stimuli and chronic stress leads to a parallel decrease in hypothalamus-pituitary-gonadal axis a...

Ngày tải lên: 09/08/2014, 14:22

... positions equivalent to the Oe1andNe2ofthe missing Gln30. Interestingly, replacement of this residue by Glu had little effect but replacement by Lys yielded an enzyme too unstable to purify [30]. In E. ... the SOD assay. Polyacrylamide gel electrophoresis (PAGE) Native 8% polyacrylamide gels (acrylamide : N,N¢-methyl- enebisacrylamide, 29 : 1, w/w) containing NaCl/Tris, pH 8.8 utilized...

Ngày tải lên: 21/02/2014, 01:21