Báo cáo y học: "Antigen receptor signaling in the rheumatic diseases" doc

... [2,3]. In addition to antigen binding, there are many levels of regulation in this signaling pathway. The SFKs themselves are tightly regulated by phosphorylation of their inhibitory C- terminal tyrosine ... domains of Syk family kinases, ZAP-70 and Syk. The Syk kinases are activated upon binding to phospho-ITAMs and phosphorylation by the SFKs. Once activated, the Syk kinases p...

Ngày tải lên: 09/08/2014, 01:22

... regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 2001, 293:306-311. 49. O’Donnell K, Harkes IC, Dougherty L, Wicks IP: Expression of receptor tyrosine kinase ... with C4-binding pro- tein; only free protein S is active as a cofactor for acti- vated protein C and a ligand for the TAM receptor kinases. In the absence of free protein S, t...

Ngày tải lên: 12/08/2014, 14:22

... NE in the lower respiratory system, is thought to play an essential role in limiting host tissue injury at sites of inflammation [14]. The clinical impor- tance of AAT is highlighted by an increased ... Foundation. Acknowledgements The authors thank all the participants included in the Swedish neonatal screening study and, E Szemberg Ringdahl and I Björk at the Department o...

Ngày tải lên: 12/08/2014, 15:21

... with vitamin E, vitamin C, or glutathione improves insulin sensitivity in insulin-resistant indi- viduals (16,62). The acute effects of hyperglyce- mia-dependent endothelial cells dysfunction ... superoxide by the mitochondrial electron transport chain would nor- malize the pathways involved in the development of the oxidative stress (68). If our findings are proven b...

Ngày tải lên: 26/10/2012, 09:39

... exercising and muscle activity can stimulate venolymphatic return due to external compression on the vessels; the au- thors suggest the use of the term ‘myolymphokinetic therapy’ when these ... Godoy JMF, Godoy MFG, Batigalia F. Preliminary evaluation of a new, more simplified physiotherapy technique for lymphatic drainage. Lymphology 2002;35:91-3. 2. Godoy JMP, Braile DM, Godoy...

Ngày tải lên: 26/10/2012, 09:39

... re-established. The increase of the oxygen gradient facilitates the transportation of toxins and inhibitors inducing thereby the wound healing [16]. As a result of the increased angiogenesis, the local ... gained over the years. Moreover, it is unknown whether the polyurethane sponges of the V.A.C. – system would have the same outcome as the polyvinylalcohol spong...

Ngày tải lên: 26/10/2012, 09:53

... according to the sensitivity of the infecting organism but conventionally have to fulfil the criteria estab- lished by Murray [24] including: antibiotic safety, thermostability, hypoallergenicity, water ... that incorporation of liquid gentamicin in bone cement spacers led to effective drug delivery with systemic safety. The most commonly used antibiotics in ALC include tobra...

Ngày tải lên: 26/10/2012, 09:53

Ngày tải lên: 03/11/2012, 11:01

... proteolysis [14]. Thus, integrin-dependent cell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensing of glutamine-induced hepatocyte swelling by ... hypoosmotic hepatocyte swelling [12,13], insu- lin-induced hepatocyte swelling is registrated by the integrin system, leading to a Src-dependent activation of the p38-type MAPK and the...

Ngày tải lên: 18/02/2014, 16:20

... ways: the plant system uses mainly electrostatic interactions, as indicated by the steep decrease in the rate constant with increasing ionic strength and its low k 8 . P. laminosum relies on hydrophobic ... possibility is that primitive cyano- bacteria at the time of chloroplast origin had poorly defined interactions between Cyt f and plastocyanin and/or plasto- cyanin and photosyste...

Ngày tải lên: 21/02/2014, 01:21