Báo cáo y học: "Consensus Guidelines on Practical Issues of Immunotherapy–Canadian Society of Allergy and Clinical Immunology (CSACI)" docx

... Commit- tee on Clinical Immunology and Allergy, Royal College of Physicians and Surgeons of Canada, Specialty Training Committee in Clinical Immunol- ogy and Allergy Recommendations on Immunotherapy References 1. ... London, Ontario; D. William Moote, Division of Clinical Immunology and Allergy, University of Western Ontario, London, Ontario; P. Small, Associ...

Ngày tải lên: 08/08/2014, 21:20

... zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and monocytes/macrophagesGelatin zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and ... 2 Gelatin zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and THP-1 cellsGelatin zymography of culture medium conditioned by fibroblast-like synoviocyt...

Ngày tải lên: 09/08/2014, 07:20

... mutation of arginine 94 to glutamic acid strongly affects the interaction of SOCS-3 with the double phosphorylated peptide pY429pY431 (pYpY). In comparison, the muta- tion only marginally reduces ... comparison, Fig. 2. Comparison of SOCS-3 binding to pY343, pY401 and pY429pY431 of the human EpoR (A) and sensogram showing the interaction of serial dilutions of SOCS-3 and pep...

Ngày tải lên: 24/03/2014, 00:21

... A competition of the corresponding rhamnosyl transferases may provide a mechanism for regulation of the content of long-chain (S-type) and short-chain (R-type) LPS species on the cell surface by an ... b)andthesiteofattachmentof QuiNActoRha(atposition2or3)aswellaswith O-acetylation and amidation of the GalNA derivatives (Table 3). Because O-acetylation and amidation, which are...

Ngày tải lên: 24/03/2014, 03:21

... ratio of Rha to Man was 1 : 1. Abso- lute configuration analysis demonstrated that Man has a D configuration and Rha an L configuration. On methylation analysis, 2,3,4-tri-O-methyl-6-deoxyhexose, ... length of the fatty acid on the acyoxyacyl group to be mainly 15, confirming the result of the compositional analysis. In the minor triacylated lipid A, the fragmentation patterns of th...

Ngày tải lên: 31/03/2014, 23:20

... growth, hypotension*, hypoglycemia* ► Patient has been receiving high-dose ICS therapy for 3-6 months: ≥500 μg/day of fluticasone; ≥1000 μg/day of budesonide/beclomethasone; or >1000 μg/day of ciclesonide ► ... president of the Canadian Network for Respiratory Care and co-chief editor of Allergy, Asthma and Clinical Immunology. He has received consulting fees and honora...

Ngày tải lên: 08/08/2014, 21:20

... Department of Health: Expert Scientific Group on phase one clinical trials: a consultation [http://www.dh.gov.uk/Consulta- tions/LiveConsultations/LiveConsultationsArticle/fs/en?CONTEN T_ID=4137501&chk=x%2BoJ/%2B] Available ... and their potential side effects, a reliable strategy for identifying nonresponders as soon as possible – ideally even before initiation of therapy – wou...

Ngày tải lên: 09/08/2014, 08:22

... 115:3083-3092. 14. Jonsson MV, Szodoray P, Jellestad S, Jonsson R, Skarstein K: Association between circulating levels of the novel TNF family members APRIL and BAFF and lymphoid organization in pri- mary Sjögren's ... expressed mainly on B cells, these cells are the major consumers of these cytokines. BAFF is produced constitutively by stromal cells within lym- phoid organs [6...

Ngày tải lên: 09/08/2014, 08:23

... H, Yagi H, Tokura Y, Norris DA, Taki- gawa M: Keratinocytes from patients with lupus erythemato- sus show enhanced cytotoxicity to ultraviolet radiation and to antibody-mediated cytotoxicity. ... the generation of pyrimidine dimers. Single-stranded breaks are sensed by the ATR (ataxia telangiectasia and rad3 related) kinase, which orchestrates repair pathways and activation of p53....

Ngày tải lên: 09/08/2014, 08:23

... need for prolonged S-phase may pose problems in clinical applications with many in vivo targets under- going only limited levels of replication and division [46]. Upon invasion, a 3-stranded heteroduplex ... excision repair pathway (NER) (Figure 1B) primarily corrects bulky adducts and pyrimidine dimers Figure 1 P P P P Holliday junction formation and resolution MRN complex CtIP...

Ngày tải lên: 10/08/2014, 05:21