Báo cáo y học: "Consensus Guidelines on Practical Issues of Immunotherapy–Canadian Society of Allergy and Clinical Immunology (CSACI)" docx
Báo cáo y học: "Consensus Guidelines on Practical Issues of Immunotherapy–Canadian Society of Allergy and Clinical Immunology (CSACI)" docx
... Commit-
tee on Clinical Immunology and Allergy, Royal
College of Physicians and Surgeons of Canada,
Specialty Training Committee in Clinical Immunol-
ogy and Allergy Recommendations on
Immunotherapy
References
1. ... London,
Ontario; D. William Moote, Division of Clinical
Immunology and Allergy, University of Western Ontario,
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Báo cáo y học: "CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes" pptx
... zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and monocytes/macrophagesGelatin zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and ... 2
Gelatin zymography of culture medium conditioned by fibroblast-like synoviocytes (FLS) and THP-1 cellsGelatin zymography of culture medium conditioned by fibroblast-like synoviocyt...
Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx
... mutation of arginine 94 to glutamic acid strongly affects
the interaction of SOCS-3 with the double phosphorylated
peptide pY429pY431 (pYpY). In comparison, the muta-
tion only marginally reduces ... comparison,
Fig. 2. Comparison of SOCS-3 binding to pY343, pY401 and
pY429pY431 of the human EpoR (A) and sensogram showing the
interaction of serial dilutions of SOCS-3 and pep...
Báo cáo Y học: Structural studies on the core and the O-polysaccharide repeating unit of Pseudomonas aeruginosa immunotype 1 lipopolysaccharide pot
... A
competition of the corresponding rhamnosyl transferases
may provide a mechanism for regulation of the content of
long-chain (S-type) and short-chain (R-type) LPS species on
the cell surface by an ... b)andthesiteofattachmentof
QuiNActoRha(atposition2or3)aswellaswith
O-acetylation and amidation of the GalNA derivatives
(Table 3). Because O-acetylation and amidation, which are...
Báo cáo Y học: Structural study on lipid A and the O-specific polysaccharide of the lipopolysaccharide from a clinical isolate of Bacteroides vulgatus from a patient with Crohn’s disease ppt
... ratio of Rha to Man was 1 : 1. Abso-
lute configuration analysis demonstrated that Man has a
D
configuration and Rha an
L
configuration. On methylation
analysis, 2,3,4-tri-O-methyl-6-deoxyhexose, ... length of the
fatty acid on the acyoxyacyl group to be mainly 15,
confirming the result of the compositional analysis. In the
minor triacylated lipid A, the fragmentation patterns of th...
Báo cáo y học: "Adrenal suppression: A practical guide to the screening and management of this under-recognized complication of inhaled corticosteroid therapy" pptx
... growth, hypotension*,
hypoglycemia*
► Patient has been receiving high-dose ICS therapy for 3-6 months: ≥500 μg/day of fluticasone; ≥1000 μg/day of
budesonide/beclomethasone; or >1000 μg/day of ciclesonide
► ... president of the Canadian Network for Respiratory
Care and co-chief editor of Allergy, Asthma and Clinical Immunology. He has
received consulting fees and honora...
Báo cáo y học: "Safety concerns on the development of novel therapeutic drugs" docx
... Department of Health: Expert Scientific Group on phase one
clinical trials: a consultation [http://www.dh.gov.uk/Consulta-
tions/LiveConsultations/LiveConsultationsArticle/fs/en?CONTEN
T_ID=4137501&chk=x%2BoJ/%2B]
Available ... and
their potential side effects, a reliable strategy for identifying
nonresponders as soon as possible – ideally even before
initiation of therapy – wou...
Báo cáo y học: "Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis" pot
... 115:3083-3092.
14. Jonsson MV, Szodoray P, Jellestad S, Jonsson R, Skarstein K:
Association between circulating levels of the novel TNF family
members APRIL and BAFF and lymphoid organization in pri-
mary Sjögren's ... expressed mainly on B cells, these cells are
the major consumers of these cytokines.
BAFF is produced constitutively by stromal cells within lym-
phoid organs [6...
Báo cáo y học: "Shining light on lupus and UV" pptx
... H, Yagi H, Tokura Y, Norris DA, Taki-
gawa M: Keratinocytes from patients with lupus erythemato-
sus show enhanced cytotoxicity to ultraviolet radiation and to
antibody-mediated cytotoxicity. ... the generation of pyrimidine
dimers. Single-stranded breaks are sensed by the ATR (ataxia
telangiectasia and rad3 related) kinase, which orchestrates
repair pathways and activation of p53....
Báo cáo y học: "An update on targeted gene repair in mammalian cells: methods and mechanisms" ppt
... need for prolonged S-phase may pose problems in
clinical applications with many in vivo targets under-
going only limited levels of replication and division [46].
Upon invasion, a 3-stranded heteroduplex ... excision repair pathway (NER) (Figure 1B)
primarily corrects bulky adducts and pyrimidine dimers
Figure 1
P
P
P
P
Holliday junction
formation and
resolution
MRN
complex
CtIP...