Báo cáo y học: "Skin Test Reactivity to Indoor Allergens Correlates with Asthma Severity in Jeddah, Saudi Arabia" docx

... of allergens yielding sensitization, plotted against asthma severity. Figure 2 Box plot of skin test reactivity to the differ- ent indoor allergens studied. Indoor Allergens and Asthma Severity ... increase in the prevalence of asthma has been almost entirely an increase in that of perennial asthma, and a Original Article Skin Test Reactivity to Indoor...

Ngày tải lên: 08/08/2014, 21:20

... directly by importin a. TotestifNLD-Iwouldbindtoimportina, we first performed a binding assay using in vitro translated importin a and recombinant GST–NLD-I fusion protein. The GST fusions with ... 25480–25487. 35. Gooding, C., Roberts, G.C. & Smith, C.W. (1998) Role of an inhibitory pyrimidine element and polypyrimidine tract binding protein in repression of a regulated alpha-tropom...

Ngày tải lên: 18/03/2014, 01:20

... patients carrying a PTPN22 1858T allele was 5.5 years younger com- pared to patients without such a genotype (CT and TT geno- type 45.5 years versus CC genotype 51.0 years; p = 0.029), in line with a ... been found to be associated also with type I diabetes, systemic lupus erythematosus and autoimmune thyroiditis, suggesting a genetic predisposition towards generalized T cell autoim...

Ngày tải lên: 09/08/2014, 08:22

... patients correlates with the inflammatory state of the disease Extracellular proteases are secreted in SF by infiltrating inflam- matory cells and/or by stromal cells stimulated by inflammatory cytokines ... other factors may explain the failure of MMP inhibitors in clinical trials. For instance, some members of the MMP family were recently shown to exert an anti-inflammatory activ...

Ngày tải lên: 09/08/2014, 08:22

... and intra-articular injec- tion with triamcinolone acetonide. The ability of ritonavir to inhibit cytochrome P450 3A4 (CYP 3A4) is exploited to increase the bioavailbility of other PIs and increase ... Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1- infected patient receiving therapy with ritonavir-lopinavir. Clin Infect Dis 2008, 47:e97-9. 14....

Ngày tải lên: 10/08/2014, 05:21

... of healthy individuals [11-15]. Care has been taken to fully specify the instrumentation type, sampling mode and analysis tools in order to allow inclusion of this study in the growing database ... ancer patients: behaviorally with morning exercise; pharmacologically with evening melatonin or photody- namically with morning light therapy among other cir- cadian tuning strategies...

Ngày tải lên: 10/08/2014, 09:20

... rebleed- ing. Patients with recurrent haemoptysis were included at the first episode only. Definitions 1. Severity of haemoptysis The severity of haemoptysis on admission was assessed according to ... or nearby the intensive care unit (ICU). In this study, we analyzed a large series of unselected patients with severe haemoptysis referred to a single respi- ratory intensive care...

Ngày tải lên: 12/08/2014, 15:20

... no genetic testing would be clinically indicated. Instead, the clinical relevance of the finding is likely to come through better understanding of the RA pathophysiology and may lead to new therapeutic targets. Contrary ... vitronec- tin, fibronectin, osteopontin, sialoprotein, thrombospondin, fibrinogen, von Willebrand factor, tenascin, agrin, matrix metal- loproteinases, and prothrombin...

Ngày tải lên: 09/08/2014, 10:20

... thereby indicating brain injury in this setting. The mechanisms responsible for this rise in NFL remain to be determined. Indeed, from a virological perspective, it is uncertain whether the increase ... increase in NFL for subject 6012 was at day 59 and for subject 6011 the inflection point showing the initial increase was delayed to 86 and 99 days. In the two subjects with incr...

Ngày tải lên: 10/08/2014, 05:20

... transcrip- tion activator in angiogenesis [11]. Hypermethylation silencing of SOCS (the Suppressor of Cytokine Signal- ing) genes leads to reactivation of STAT pathway, resulting in the resistance to ABT-869, ... omising multi-targeted tyrosine kinase inhibitor [12]. STAT pathway also triggers the activity of receptor-a ssociated Janus kinase (JAK) family members and cross-talks with...

Ngày tải lên: 10/08/2014, 21:23