Báo cáo y học: "GOAL: What Have We Learned" pps

... somewhat more stringent in their acceptance of symptoms that define “well-controlled asthma” or “acceptable control.” To fully appreciate the study, it is necessary to highlight two previous hypothesis-generating studies 2,3 that ... What Have We Learned? Timothy K. Vander Leek, MD, FRCPC Division of Clinical Immunology and Allergy, Department of Pediatrics, University of Alberta, Edmon...

Ngày tải lên: 08/08/2014, 20:23

... indepen- dently. In summary, this case illustrates the typical clinical manifestations of hyper-IgM syndrome due to AID deficiency, which differ significantly from those of hyper-IgM syndrome due ... maternal grand- mother were sisters. Examination revealed normal height and weight, cervical lymphadenopathy, a left middle-ear effusion, and bilateral lower-lobe expiratory crackles. A chest rad...

Ngày tải lên: 08/08/2014, 21:20

... may be a complex, multigene trait. The alleles are present in the population and, when expressed individu- ally, may have a relatively weak effect; however, they can interact synergistically ... memory in PCP-treated mice, they performed cotreatment with a dopamine-1 receptor antagonist, SCH23390, and a serotonin 5-hydroxytryptamine (5- HT)(1A) subtype receptor antagonist, WAY100635. They f...

Ngày tải lên: 08/08/2014, 23:21

Ngày tải lên: 09/08/2014, 01:22

... cata- lysed by a family of calcium-dependent enzymes named peptidyl arginine deiminase (PAD, EC 3.5.3.15) (reviewed in [7]). These enzymes are present in several different cell and tissue types, ... added and slides were incubated overnight at room temperature. Slides were then washed in PBS, followed by incubation for 30 min at room temperature with secondary antibody (biotinylated goat anti...

Ngày tải lên: 09/08/2014, 06:22

... clearly increased the risk of cardiovascular events, confirming a previous publication by Turesson and colleagues [2]. The real importance of this study, however, may lie in the final analysis, ... multivariate analysis where potential confounders were also included, including age and sex, other traditional risk factors, and disease activity by the Disease Activity Score as well as the Health...

Ngày tải lên: 09/08/2014, 10:22

Ngày tải lên: 09/08/2014, 13:22

... spectroscopy and mass spectrometry, as well as a variety of other approaches, so producing a standardized workflow is difficult. is is further complicated by the fact that many in the community do ... unifying description, and instead a user must define first which description is most appropriate to them depending on what biological system they work on. So why is the metabolomics communit...

Ngày tải lên: 11/08/2014, 12:20

... may be an appropriate response, although we were not able to demonstrate a relationship between SP-D level and BAL HIV viral load. SP-D suppresses lymphocyte function by inhibiting T lymphocyte ... and inhibitory activities exceeding MBL[12], we investigated the possibility that high levels of SP-D were associated with low viral loads in BAL. SP-D levels were found to have a weak relati...

Ngày tải lên: 12/08/2014, 15:20

... preaxial polydactyly was still present. Despite evidence for the involvement of the sonic hedgehog pathway in polydactyly, no evidence was found for a role for this pathway in the polydactyly observed ... phenotype were only reproduced in double knockout mice, lacking both EphB2 and EphB3, indicating a degree of functional redundancy in these receptors. Preaxial polydactyly was exclusi...

Ngày tải lên: 08/08/2014, 17:20