... activation and cytochrome c release. To extendtheir study into the clinical realm, th e investigators pro-spectively r andomized 34 patients wit h NYHA class III and IV heart failure to receive ... 23:99-109.76. Edgington TS, Mackman N, Fan ST, Ruf W: Cellular immune and cytokinepathways resulting in tissue factor expression and relevance to septicshock. Nouv Rev Fr Hematol 1992, 34(Suppl):S15-27.77. ... Schorah CJ, Downing C, Piripitsi A, Gallivan L, Al-Hazaa AH, Sanderson MJ,Bodenham A: Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients....