Báo cáo khoa học: "Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration" doc

... inhibited the expression of VEGF, thereby suppressing the growth of hepatocarcinoma tumors in mice [87]. In addition, no noticeable increase in inflammatory cytokines, including interferon-a and ... emerging therapeutic strategy and has been widely investigated. Despite a few promising clinical trials, effectively delivering siRNA in vivo remains a pivotal challenge in transl...

Ngày tải lên: 06/03/2014, 01:23

... dialogue system. In Pro- ceedings of IJCAI 2009. M. Huber, M. Rickert, A. Knoll, T. Brandt, and S. Glasauer. 2008. Human-robot interaction in handing-over tasks. In Proceedings of IEEE RO-MAN 2008. ... Proceedings of the AISB 2005 Creative Robotics Symposium. C. Callison-Burch, M. Osborne, and P. Koehn. 2006. Re-evaluating the role of BLEU in ma- chine translation research...

Ngày tải lên: 17/03/2014, 01:20

Ngày tải lên: 07/08/2014, 18:21

... dis- tribution of the energy between the overall tumbling and the internal mobility, and is indicative of the degree of internal restraint of each 15 N– 1 H vector motion. In Fig. 4, most of the points ... Universita ` di Udine, Italy Homeodomains (HDs) comprise a very well-known class of DNA-binding domains occurring in a large family of transcription activators involve...

Ngày tải lên: 18/02/2014, 16:20

... superimposed structures of conomarphin (red) and L-Phe13-conomarphin (gray). The side chain of L-Phe13 might cause spatial hindrance to the side chain of Lys9 and Hyp10 in forming the tight loop as in conomarphin. ... side chain of Lys9, Hyp10 and D-Phe13 of cono- marphin is shown in stick mode, and the side chain of L-Phe13 in L-Phe13-conomar- phin is shown as a g...

Ngày tải lên: 18/02/2014, 17:20

... activity of trappin-2 is independent of its intrinsic inhibitory activity and that trappin-2 and its uninhibitory mutant are bactericidal because fewer surviving CFU were present after 3 h of incubation ... (µ M) % of surviving CFU Trappin-2 Trappin-2 + heparin Trappin-2 + NaCl C. albicans 40 50 60 70 80 90 100 0 5 10 15 20 25 30 35 % of surviving CFU Trappin-2 Trappin-2 + hepa...

Ngày tải lên: 18/02/2014, 17:20

... and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of 1 nm. Thermal stability of Rep245 was measured by incu- bating the protein at 60, 70 and 80 °C for 30 min and ... Significantly, following incubation with M13 mp18 single- stranded DNA in the presence of a ribonucleotide mixture containing [ 32 P]ATP[aP], Rep245 was actually found to be c...

Ngày tải lên: 18/02/2014, 18:20

... Picolinic acid in milk, pancreatic juice and intestine: inadequate for role in zinc absorption. Am J Clin Nutr 35, 1–9. 16 Evans GW & Johnson PE (1980) Characterization and quantitation of a zinc binding ... with cerebral malaria and in the brain of a murine model of the syndrome [18,19]. Interestingly, picolinate is reportedly able to prevent the neurotoxic effects of...

Ngày tải lên: 19/02/2014, 02:20

... com- prising two domains that are responsible for binding substrate and NADP cofactor. The detailed structural information might expedite the discovery of novel SDH inhibitors and further of antimicrobial ... from the slope and intercept values of the linear fit in a Lineweaver–Burk plot. To test the enzymatic activity of HpSDH in the presence of quinate, the assay solution...

Ngày tải lên: 19/02/2014, 05:20

... kinases, including src and fyn, Bruton’s tyro- sine kinase (btk) and syk in an in vitro kinase assay using S6K1 and 2 as substrates. As shown in Fig. 1C, all tested tyrosine kinases, in particular ... 2023 Ribosomal protein S6 kinase (S6K) is a serine ⁄ threon- ine kinase belonging to the family of AGC kinases, which includes protein kinase A (PKA), protein kinase B (PKB ⁄ Akt...

Ngày tải lên: 19/02/2014, 07:20