Báo cáo khoa học: "Collaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphere" ppsx
Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc
... alanine scanning of the L-CDR3 and H-CDR3 loops of antibody mAb4E11.This scanning allowed us to identify the residues of these loops that contributed to the energetics and kinet-ics of the interaction ... mAb4E11 and its antigen.It showed that the residues of diversity, H-Trp96 and H-Glu97, and the residues of junction, L-Trp96,H-Gly95 and H-Gly98, constituted major hotspots of binding energy. ... VLcontain the residues of diversity and junction, encoded by the D segment, and the VH-D, D-JH, and VL-JLjunctions [17]. They are located at the center of the antibody combining site...
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Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt
... that the isolated canonical EF-hand alone has an intrinsic tendency toform a dimer, which is in agreement with the EF-hand pairing paradigm. Clearly, the canonical EF-hand motif alone is able ... engineeredprotein CD2 .STIM1. EF increased, indicating that the inserted EF-hand motif at least partially maintains the natural helical structure after grafting. The Ca2+dis-sociation constant of CD2 .STIM1. EF ... ‘punctae’ and aggregates near the plasma membrane [1,6]. The N-terminal region of STIM1 contains a canonical EF-hand motif and a pre-dicted SAM domain. Stathopulos et al. [23,24] isolated the...
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Báo cáo khoa học "ADIABATIC TEMPERATURE RISE AND REACTION RATE OF MASS STRUCTURE IN LOTTE CENTER HANOI PROJECT " pptx
... measured results (Center) The value compared between measured and analyzed (Center) ADIABATIC TEMPERATURE RISE AND REACTION RATE OF MASS STRUCTURE IN LOTTE CENTER HANOI PROJECT Dr. KIM ... thermal crack index is over 1.0 and a curing time of mass- section foundation decreases within 18 days through minimizing binders in concrete and adjusting hydration heat and delay setting time between ... adiabatic temperature rise and a reaction rate for evaluate thermal stress. And the other is how to control quality of mass concrete with reducing internal restraining stress through finite analysis....
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Báo cáo khóa học: O-acetylation and de-O-acetylation of sialic acids in human colorectal carcinoma docx
... (1989) O-acetylation and de -O-acetylation of sialic acids. O-acetylation of sialic acids in the rat liver Golgi apparatus involves an acetyl intermediate and essential histidine and lysine residues–a ... questions concerning the occurrence and enzymatic processes involved in the O-acetylation and de -O-acetylation of sialic acids in human colonic tissues.Correspondence to J. Tiralongo, Institute for ... free sialic acids isolated from the mucosa of matched resection margin and colorectal carcinoma tissue. Sialic acids were isolated and analysed by HPLC and GC-MS as described in Materials and...
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Báo cáo khoa học: Protein stabilization by compatible solutes Effect of diglycerol phosphate on the dynamics of Desulfovibrio gigas rubredoxin studied by NMR docx
... Protein stabilization by compatible solutes Effect of diglycerol phosphate on the dynamics of Desulfovibrio gigas rubredoxin studied by NMR Pedro Lamosa1, David L. ... dynamic behaviour of proteins in the presence of solutes is expected to shed light on the stabilization phenomenon. Desulfovibrio gigas rubredoxin (RdDg), a small iron–sulfur protein with a hydrophobic ... solutecompletely restricts concerted motions of groups on largertime-scales. The influence of DGP addition on the order parameters of RdDg is of the same magnitude as the effect of ligandbinding reported...
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Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx
... point mutations in the native Hsp90 of yeast render cells much more sensitive to Hsp90 inhibitor drugs To test whether mutations in the native Hsp90 chaperone of yeast influence sensitivity to Hsp90 ... of Hsp90 system cochaperones and plasma membrane ATP binding cassette (ABC) transporters can sensitize cells to Hsp90 drugs Hsp90 works in association with a number of cochaperoneproteins. These ... displaces the bound GA [33].If the increased Hsp90 drug sensitivity of the T101I and A587T hsp82 mutants (Fig. 1A) was due to these mutationscausing tighter drug binding to the chaperone, thesemutations...
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Báo cáo khoa học: Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain pdf
... al. Oxymethylene diadenosine polyphosphate analogs FEBS Journal 276 (2009) 15461553 ê 2009 The Authors Journal compilation ê 2009 FEBS 1551 Novel diadenosine polyphosphate analogs with oxymethylene ... tounderstand their biological functions has been through the use of NpnNÂ analogs. Here, we present the results of studies using novel diadenosine polyphosphate analogs, with an oxymethylene group replacing ... cleavage ofdinucleoside polyphosphate molecules modified in theirADP moieties. In addition, none of the oxymethylene analogs investigated inhibited the hydrolysis of Ap4Acatalyzed by the E. coli...
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Báo cáo khoa học: Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 pot
... (5Â-TCCCGTGTGTGCAGACCATCTTGAAT -3 ), H528A forward primer(5Â-TCCCGTGTGTCAAGACGCTCTTGAAT -3 ) or H 52 8Sforward primer (5Â-TCCCGTGTGTCAAGACTCTCTTGAAT -3 ) and reverse primer (5Â-AGTCCCGGGGTGTTCATGTATGCTC -3 ). ... C, Cai Z, Kim YC, Kumar R, Yuan F, Shi PY,Kao C & Luo G (2005) Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV ... 59795986 ê 2007 The Authors Journal compilation ê 2007 FEBS Effects on protease inhibition by modifying of helicase residues in hepatitis C virus nonstructural protein 3 Goăran Dahl1, Anja Sandstroăm2,...
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Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf
... Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 Maya Guncheva1, Ivaylo Ivanov2, ... atoms of the main chain CO groups of LeuB387 and TrpB240, Od1atom of AsnB241, and Oc atom of SerB386 and is expected to stabilize the positive charge of ArgB263.All of these views remain arguable, ... of some arylamide substrates docked in the active site of penicillin acylase by AM1 calculations. Amino acid residues of the enzyme are at their X-ray coordinates [19]. Substrates having local...
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Báo cáo khoa học: NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon ¨ Methanosarcina mazei Go1 pot
... to the NrpRI ⁄ NrpRII complex decreases the binding affinity of NrpRI to the operator as well asdecreasing the NrpRII binding affinity to the general transcription factors, potentially by inducing ... studied the binding properties of NrpRII to the general transcription factors – TATA-binding protein(TBP) and the archaeal homolog of the eukaryotic general transcription factor TFIIB (TFB). MBP– NrpRII, ... Consequently, potential formation of a complex between NrpRI and NrpRII, as well as between NrpRII and general transcription factors, were investigated and the effects of 2-oxoglutarate on binding were...
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Báo cáo khoa học: Relaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka pptx
... FEBS 4993 MINIREVIEWRelaxin-3⁄ insulin-like peptide 7, a neuropeptide involved in the stress response and food intake Masaki Tanaka Department of Basic Geriatrics, Kyoto Prefectural University ... Relaxin-3 is so named because it has a motif thatcan interact with the relaxin receptor. By contrast to other relaxins,relaxin-3 is mainly expressed in the brain and testis. In rodent brain, ana-tomical ... administeredrelaxin-3 induces Fos expression in the osmosensitiveareas in rat brain and facilitates water intake. Peptides31, 1124–1130.36 Shiba K, Kageyama H, Takenoya F & Shioda S (2010)Galanin-like...
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Báo cáo khoa học: "Collaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphere" ppsx
... because of the cost of the drug, the replacement of sled-dogs by machines decreased remarkably the incidence of alveolar echinococcosis in the island. However, with the presence of other definitive ... Taken together, these findings indicate that invasion of young infected foxes into the territories left by the hunted foxes could maintain or increase the preva-lence rate of infection. In Japan, ... mkamiya@rakuno.ac.jpCollaborative control initiatives targeting zoonotic agents of alveolar echinococcosis in the northern hemisphereMasao Kamiya*OIE Reference Laboratory for Echinococcosis and Laboratory of Environmental...
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Báo cáo khoa học: "general overview with a seasonal assessment silver fir forest in the Vosges mountains (France)" docx
... class="bi x0 y0 w1 h0" alt="" Review articleAluminium toxicity in declining forests: a general overview with a seasonal assessment in a silver fir forest in the Vosges mountains ... performant Ca/Al ratio and is used in a declining fir stand in the Vosges mountains (eastern France). A potential Al toxicity phase was observed in winter only, namely during ... with reasonable as-sumptions.APPLICATION: A CASE STUDY IN A DECLINING SILVER FIR FOREST IN THE VOSGES MOUNTAINS (NORTH-EASTERN FRANCE)To illustrate the previous considerations,we...
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Báo cáo khoa học: "Marjolin''''s ulcers: theories, prognostic factors and their peculiarities in spina bifida patients" ppsx
... AccessMarjolin’s ulcers: theories, prognostic factors and their peculiarities in spina bifida patientsPeter M NthumbaAbstractBackground: Due to improved care, more and more children born with spina bifida ... different prognostic factors, with a view to applying these to spina bifida patients. This understanding would aid thehealthcare worker in developing programs suited to agrowin g population of spina ... 2 Marjolin’s ulcer with sinuses extending into the thigh and labia majora. One sinus was found in the anus, and another in the vagina. Note benign appearance of ulcer marginssurrounding a flat...
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Báo cáo khoa học: " Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors" docx
... CentralPage 1 of 7(page number not for citation purposes)Radiation OncologyOpen AccessResearch Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral ... pro-tocol for patients with medically inoperable small periph-eral stage I lung cancer and single small peripheral lung metastases. Continuous tracking of respiratory tumor motion with Synchrony and ... using stereotactic radiosurgery with real-time tumor motion tracking to treat small peripheral lung tumors.Methods: Eligible patients were treated over a 24-month period and followed for a minimum...
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Từ khóa: Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)QUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ